BG37378A3 - Method for preparing acylated benzothiophens - Google Patents

Method for preparing acylated benzothiophens

Info

Publication number
BG37378A3
BG37378A3 BG056062A BG5606282A BG37378A3 BG 37378 A3 BG37378 A3 BG 37378A3 BG 056062 A BG056062 A BG 056062A BG 5606282 A BG5606282 A BG 5606282A BG 37378 A3 BG37378 A3 BG 37378A3
Authority
BG
Bulgaria
Prior art keywords
benzothiophens
preparing acylated
acylated
preparing
benzothiophenes
Prior art date
Application number
BG056062A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mary Peters
Charles Jones
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/331,046 external-priority patent/US4380635A/en
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG37378A3 publication Critical patent/BG37378A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG056062A 1981-04-03 1982-04-01 Method for preparing acylated benzothiophens BG37378A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24633581A 1981-04-03 1981-04-03
US24633381A 1981-04-03 1981-04-03
US33104581A 1981-12-16 1981-12-16
US06/331,046 US4380635A (en) 1981-04-03 1981-12-16 Synthesis of acylated benzothiophenes

Publications (1)

Publication Number Publication Date
BG37378A3 true BG37378A3 (en) 1985-05-15

Family

ID=27500218

Family Applications (1)

Application Number Title Priority Date Filing Date
BG056062A BG37378A3 (en) 1981-04-03 1982-04-01 Method for preparing acylated benzothiophens

Country Status (13)

Country Link
EP (1) EP0062505B1 (fi)
BG (1) BG37378A3 (fi)
DE (1) DE3264853D1 (fi)
DK (1) DK151382A (fi)
ES (1) ES511123A0 (fi)
FI (1) FI821161L (fi)
GB (1) GB2096608B (fi)
GR (1) GR78364B (fi)
HU (1) HU191084B (fi)
IL (1) IL65379A0 (fi)
PL (1) PL130584B1 (fi)
PT (1) PT74693B (fi)
RO (1) RO84584B (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4117512A1 (de) * 1991-05-25 1992-11-26 Schering Ag 2-phenylbenzo(b)furane und -thiophene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
USRE39049E1 (en) 1992-07-28 2006-03-28 Eli Lilly And Company Methods for inhibiting bone loss
TW366342B (en) 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
USRE38968E1 (en) 1992-07-28 2006-02-07 Eli Lilly And Company Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride
US5462949A (en) * 1993-12-21 1995-10-31 Eli Lilly And Company Methods of inhibiting fertility in women
US5478847A (en) 1994-03-02 1995-12-26 Eli Lilly And Company Methods of use for inhibiting bone loss and lowering serum cholesterol
CA2145614A1 (en) * 1994-03-31 1995-10-01 Jeffrey A. Dodge Intermediates and processes for preparing benzothiophene compounds
US5523416A (en) * 1994-07-22 1996-06-04 Eli Lilly And Company Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes
US5731436A (en) * 1994-08-31 1998-03-24 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
US5631369A (en) * 1994-08-31 1997-05-20 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
CO4410190A1 (es) 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO
US5629425A (en) * 1994-09-19 1997-05-13 Eli Lilly And Company Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
PL182493B1 (pl) * 1995-02-28 2002-01-31 Lilly Co Eli Nowe pochodne benzotiofenu, nowe związki pośrednie i sposób wytwarzania nowych pochodnych benzotiofenu oraz środek farmaceutyczny
US6395755B1 (en) * 1995-03-10 2002-05-28 Eli Lilly And Company Benzothiophene pharmaceutical compounds
EP0738725A3 (en) * 1995-04-21 1997-03-05 Lilly Co Eli Benzothiophenes with basic side chains
US5606076A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
BR9608847A (pt) * 1995-06-07 1999-06-08 Lilly Co Eli Processo para a síntese de derivados de ácido vinil sulfênico
WO1997034888A1 (en) * 1996-03-19 1997-09-25 Eli Lilly And Company SYNTHESIS OF 3-[4-(2-AMINOETHOXY)-BENZOYL]-2-ARYL-6-HYDROXY-BENZO[b]THIOPHENES
IN183239B (fi) * 1996-09-25 1999-10-09 Lilly Co Eli
US5916916A (en) * 1996-10-10 1999-06-29 Eli Lilly And Company 1-aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods
WO1998048787A1 (en) * 1997-04-30 1998-11-05 Eli Lilly And Company INTERMEDIATES AND A PROCESS FOR PREPARING BENZO[b]THIOPHENES
CA2287922A1 (en) * 1997-04-30 1998-11-05 Eli Lilly And Company Intermediates and processes for preparing benzo[b]thiophenes
CA2231013A1 (en) * 1997-04-30 1998-10-30 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceuticals
BR9809439A (pt) * 1997-04-30 2000-06-13 Lilly Co Eli Processos para preparação de benzotiofenos
CA2236254A1 (en) * 1997-04-30 1998-10-30 David Warren Hoard Process for preparing benzo¬b|thiophenes
KR20010020379A (ko) * 1997-04-30 2001-03-15 피터 지. 스트링거 치환된 벤조[ｂ]티오펜을 제조하기 위한 레지오선택적 알킬화 방법
CA2499819A1 (en) 2002-09-30 2004-04-08 A/S Gea Farmaceutisk Fabrik Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these
IT1403083B1 (it) * 2010-10-25 2013-10-04 Fidia Farmaceutici Nuova forma polimorfa di raloxifene cloridrato

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947470A (en) * 1974-06-20 1976-03-30 Smithkline Corporation Substituted benzofurans and benzothiophenes
US4001426A (en) * 1974-10-17 1977-01-04 Smithkline Corporation Substituted benzofurans and benzothiophenes
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents

Also Published As

Publication number Publication date
PT74693A (en) 1982-05-01
RO84584A (ro) 1984-07-17
PL235751A1 (fi) 1982-11-22
FI821161L (fi) 1982-10-04
PT74693B (en) 1985-01-08
RO84584B (ro) 1984-09-30
ES8304116A1 (es) 1983-02-16
GB2096608A (en) 1982-10-20
EP0062505B1 (en) 1985-07-24
DE3264853D1 (en) 1985-08-29
FI821161A0 (fi) 1982-04-02
DK151382A (da) 1982-10-04
HU191084B (en) 1987-01-28
IL65379A0 (en) 1982-05-31
ES511123A0 (es) 1983-02-16
GR78364B (fi) 1984-09-26
PL130584B1 (en) 1984-08-31
EP0062505A1 (en) 1982-10-13
GB2096608B (en) 1985-06-12

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