BG35898A3 - Method for preparing 1- (4- aryl- cyclohexyl)- piperidines - Google Patents
Method for preparing 1- (4- aryl- cyclohexyl)- piperidinesInfo
- Publication number
- BG35898A3 BG35898A3 BG8151147A BG5114781A BG35898A3 BG 35898 A3 BG35898 A3 BG 35898A3 BG 8151147 A BG8151147 A BG 8151147A BG 5114781 A BG5114781 A BG 5114781A BG 35898 A3 BG35898 A3 BG 35898A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- piperidines
- cyclohexyl
- aryl
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/38—Unsaturated compounds containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12870580A | 1980-03-10 | 1980-03-10 | |
| US19914280A | 1980-10-22 | 1980-10-22 | |
| US06/222,091 US4329353A (en) | 1980-10-22 | 1981-01-09 | 1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG35898A3 true BG35898A3 (en) | 1984-07-16 |
Family
ID=27383775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG8151147A BG35898A3 (en) | 1980-03-10 | 1981-03-09 | Method for preparing 1- (4- aryl- cyclohexyl)- piperidines |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0035902B1 (ro) |
| KR (1) | KR850000026B1 (ro) |
| AU (1) | AU538147B2 (ro) |
| BG (1) | BG35898A3 (ro) |
| CA (1) | CA1161438A (ro) |
| DE (1) | DE3166892D1 (ro) |
| DK (1) | DK107181A (ro) |
| ES (1) | ES8300743A1 (ro) |
| FI (1) | FI73428C (ro) |
| GR (1) | GR73633B (ro) |
| HU (1) | HU187362B (ro) |
| IE (1) | IE51080B1 (ro) |
| IL (1) | IL62320A (ro) |
| NO (1) | NO159793C (ro) |
| NZ (1) | NZ196441A (ro) |
| PH (1) | PH16661A (ro) |
| PL (1) | PL130480B1 (ro) |
| PT (1) | PT72641B (ro) |
| RO (2) | RO85814B (ro) |
| YU (1) | YU42236B (ro) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK139684A (da) * | 1983-04-11 | 1984-10-12 | Janssen Pharmaceutica Nv | N-aryl-alpha-amino-carboxamider |
| US5047406A (en) * | 1989-12-06 | 1991-09-10 | Warner-Lambert Co. | Substituted cyclohexanols as central nervous system agents |
| US4975445A (en) * | 1989-12-06 | 1990-12-04 | Warner-Lambert Company | Substituted cyclohexenes as central nervous system agents |
| ZA929008B (en) * | 1991-12-13 | 1993-05-21 | Bristol Myers Squibb Co | Piperazinyl- and piperidinyl-cyclohexanols. |
| CA2091204C (en) * | 1992-03-11 | 1997-04-08 | Ronald J. Mattson | Antiischemic-piperazinyl and piperidinyl-cyclohexanes |
| CN1047594C (zh) * | 1993-01-02 | 1999-12-22 | 布里斯托尔-迈尔斯斯奎布公司 | 哌嗪基或哌啶基环己醇、其制法和用途 |
| SI0921125T1 (en) * | 1997-12-05 | 2002-04-30 | F. Hoffmann-La Roche Ag | 1,3,8-Triazaspiro(4,5)decan-4-on derivatives |
| PT921125E (pt) * | 1997-12-05 | 2002-06-28 | Hoffmann La Roche | Derivados de 1,38-triaza-espiro 4,5 decan-4-ona |
| WO1999032443A1 (en) * | 1997-12-23 | 1999-07-01 | Alcon Laboratories, Inc. | Muscarinic agents and use thereof to treat glaucoma, myopia, and various other conditions |
| WO1999032489A1 (en) * | 1997-12-23 | 1999-07-01 | Alcon Laboratories, Inc. | Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3712897A (en) * | 1970-06-10 | 1973-01-23 | Lepetit Spa | Triazaspirodecanedithiones |
| CH572460A5 (ro) * | 1972-07-28 | 1976-02-13 | Ciba Geigy Ag | |
| US4048058A (en) * | 1975-08-13 | 1977-09-13 | Standard Oil Company (Indiana) | Methods to be used in reforming processes employing multi-metallic catalysts |
| US4051248A (en) * | 1975-07-14 | 1977-09-27 | E. R. Squibb & Sons, Inc. | 1,3,8-triazaspiro(4.5)decan-4-one derivatives |
| US4076821A (en) * | 1976-02-27 | 1978-02-28 | Yoshitomi Pharmaceutical Industries, Ltd. | 4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof |
-
1981
- 1981-03-03 GR GR64292A patent/GR73633B/el unknown
- 1981-03-04 CA CA000372317A patent/CA1161438A/en not_active Expired
- 1981-03-05 AU AU68092/81A patent/AU538147B2/en not_active Ceased
- 1981-03-06 KR KR1019810000729A patent/KR850000026B1/ko active IP Right Grant
- 1981-03-06 NZ NZ196441A patent/NZ196441A/en unknown
- 1981-03-09 IE IE506/81A patent/IE51080B1/en unknown
- 1981-03-09 NO NO810793A patent/NO159793C/no unknown
- 1981-03-09 DE DE8181300973T patent/DE3166892D1/de not_active Expired
- 1981-03-09 RO RO110666A patent/RO85814B/ro unknown
- 1981-03-09 RO RO81103622A patent/RO81938A/ro unknown
- 1981-03-09 FI FI810727A patent/FI73428C/fi not_active IP Right Cessation
- 1981-03-09 EP EP81300973A patent/EP0035902B1/en not_active Expired
- 1981-03-09 BG BG8151147A patent/BG35898A3/xx unknown
- 1981-03-09 DK DK107181A patent/DK107181A/da not_active Application Discontinuation
- 1981-03-09 IL IL62320A patent/IL62320A/xx unknown
- 1981-03-09 HU HU81581A patent/HU187362B/hu not_active IP Right Cessation
- 1981-03-10 YU YU620/81A patent/YU42236B/xx unknown
- 1981-03-10 PL PL1981230073A patent/PL130480B1/pl unknown
- 1981-03-10 ES ES500251A patent/ES8300743A1/es not_active Expired
- 1981-03-10 PH PH25341A patent/PH16661A/en unknown
- 1981-03-10 PT PT72641A patent/PT72641B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI810727L (fi) | 1981-09-11 |
| PH16661A (en) | 1983-12-13 |
| IL62320A0 (en) | 1981-05-20 |
| RO85814B (ro) | 1984-11-30 |
| AU6809281A (en) | 1981-09-17 |
| DE3166892D1 (de) | 1984-12-06 |
| PL130480B1 (en) | 1984-08-31 |
| NZ196441A (en) | 1984-07-06 |
| FI73428B (fi) | 1987-06-30 |
| ES500251A0 (es) | 1982-11-01 |
| EP0035902B1 (en) | 1984-10-31 |
| RO81938B (ro) | 1983-05-30 |
| HU187362B (en) | 1985-12-28 |
| YU62081A (en) | 1983-12-31 |
| EP0035902A1 (en) | 1981-09-16 |
| NO159793B (no) | 1988-10-31 |
| RO85814A (ro) | 1984-11-25 |
| IE51080B1 (en) | 1986-10-01 |
| CA1161438A (en) | 1984-01-31 |
| IL62320A (en) | 1984-06-29 |
| IE810506L (en) | 1981-09-10 |
| RO81938A (ro) | 1983-06-01 |
| NO159793C (no) | 1989-02-08 |
| PT72641A (en) | 1981-04-01 |
| GR73633B (ro) | 1984-03-26 |
| PL230073A1 (en) | 1983-04-11 |
| PT72641B (en) | 1982-11-15 |
| ES8300743A1 (es) | 1982-11-01 |
| NO810793L (no) | 1981-09-11 |
| FI73428C (fi) | 1987-10-09 |
| AU538147B2 (en) | 1984-08-02 |
| DK107181A (da) | 1981-09-11 |
| YU42236B (en) | 1988-06-30 |
| KR830005200A (ko) | 1983-08-03 |
| KR850000026B1 (ko) | 1985-02-11 |
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