BG25206A3 - A method of obtaining d 1-15-deoxoprostaglandine-e bottom 1 - Google Patents

A method of obtaining d 1-15-deoxoprostaglandine-e bottom 1

Info

Publication number
BG25206A3
BG25206A3 BG022528A BG2252873A BG25206A3 BG 25206 A3 BG25206 A3 BG 25206A3 BG 022528 A BG022528 A BG 022528A BG 2252873 A BG2252873 A BG 2252873A BG 25206 A3 BG25206 A3 BG 25206A3
Authority
BG
Bulgaria
Prior art keywords
deoxoprostaglandine
obtaining
Prior art date
Application number
BG022528A
Other languages
Bulgarian (bg)
English (en)
Inventor
Charles Sih
Original Assignee
Wisconsin Alumni Reserch Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/221,058 external-priority patent/US4031129A/en
Application filed by Wisconsin Alumni Reserch Foundation filed Critical Wisconsin Alumni Reserch Foundation
Publication of BG25206A3 publication Critical patent/BG25206A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/06Aluminium compounds
    • C07F5/061Aluminium compounds with C-aluminium linkage
    • C07F5/066Aluminium compounds with C-aluminium linkage compounds with Al linked to an element other than Al, C, H or halogen (this includes Al-cyanide linkage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/013Preparation of halogenated hydrocarbons by addition of halogens
    • C07C17/02Preparation of halogenated hydrocarbons by addition of halogens to unsaturated hydrocarbons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02Lithium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08Copper compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG022528A 1972-01-26 1973-01-25 A method of obtaining d 1-15-deoxoprostaglandine-e bottom 1 BG25206A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/221,058 US4031129A (en) 1972-01-26 1972-01-26 15-Deoxy-PGE1 and method for preparing same
US25572872A 1972-05-22 1972-05-22
US29344272A 1972-09-29 1972-09-29

Publications (1)

Publication Number Publication Date
BG25206A3 true BG25206A3 (en) 1978-08-10

Family

ID=27396893

Family Applications (3)

Application Number Title Priority Date Filing Date
BG022528A BG25206A3 (en) 1972-01-26 1973-01-25 A method of obtaining d 1-15-deoxoprostaglandine-e bottom 1
BG032229A BG25207A3 (en) 1972-01-26 1973-01-25 A method of obtaining prostaglandine e bottom 1
BG7300032232A BG25208A3 (en) 1972-01-26 1973-01-25 A method of obtaining d 1-15-deoxoprostaglandine-e bottom 1

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG032229A BG25207A3 (en) 1972-01-26 1973-01-25 A method of obtaining prostaglandine e bottom 1
BG7300032232A BG25208A3 (en) 1972-01-26 1973-01-25 A method of obtaining d 1-15-deoxoprostaglandine-e bottom 1

Country Status (17)

Country Link
JP (3) JPS5333583B2 (US20110232667A1-20110929-C00004.png)
AR (2) AR199893A1 (US20110232667A1-20110929-C00004.png)
AU (1) AU452896B2 (US20110232667A1-20110929-C00004.png)
BE (1) BE794516A (US20110232667A1-20110929-C00004.png)
BG (3) BG25206A3 (US20110232667A1-20110929-C00004.png)
CA (1) CA1014092A (US20110232667A1-20110929-C00004.png)
CH (3) CH580046A5 (US20110232667A1-20110929-C00004.png)
DD (3) DD112750A5 (US20110232667A1-20110929-C00004.png)
DE (2) DE2365927A1 (US20110232667A1-20110929-C00004.png)
ES (3) ES410962A1 (US20110232667A1-20110929-C00004.png)
FR (3) FR2181693B1 (US20110232667A1-20110929-C00004.png)
GB (3) GB1419181A (US20110232667A1-20110929-C00004.png)
IE (2) IE37106B1 (US20110232667A1-20110929-C00004.png)
IL (5) IL49286A (US20110232667A1-20110929-C00004.png)
NL (2) NL153514B (US20110232667A1-20110929-C00004.png)
RO (1) RO71588A (US20110232667A1-20110929-C00004.png)
SE (3) SE7600888L (US20110232667A1-20110929-C00004.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1018970A (en) * 1972-10-27 1977-10-11 American Home Products Corporation 15-substituted prostanoic acids
JPS5720305B2 (US20110232667A1-20110929-C00004.png) * 1973-02-28 1982-04-27
US4029693A (en) * 1975-01-20 1977-06-14 The Upjohn Company 2A,2B-Dihomo-11-deoxy-17(substituted phenyl)-18,19,20-trinor-PGE2 compounds and their corresponding esters
US4032561A (en) * 1975-05-27 1977-06-28 The Upjohn Company 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF1.sub.α compounds
US4016184A (en) * 1975-09-17 1977-04-05 The Upjohn Company 9-Deoxy-9,10-didehydro-PGD1 compounds
US4365075A (en) * 1975-09-17 1982-12-21 The Upjohn Company ω-Aryl-PGD compounds
US4029814A (en) * 1975-12-29 1977-06-14 The Upjohn Company Phenyl-substituted prostaglandin-e type analogs
US4219662A (en) * 1977-02-28 1980-08-26 The Upjohn Company 11-Deoxy-17-phenyl-PGE1 analogs
AU529883B2 (en) * 1978-09-04 1983-06-23 Australian National University, The Substituted cyclopentenones

Also Published As

Publication number Publication date
FR2181693B1 (US20110232667A1-20110929-C00004.png) 1979-01-12
DE2365513A1 (de) 1975-06-26
CH578502A5 (US20110232667A1-20110929-C00004.png) 1976-08-13
IL49286A0 (en) 1976-05-31
IL41305A (en) 1977-10-31
GB1419183A (en) 1975-12-24
GB1419182A (en) 1975-12-24
SE7600890L (sv) 1976-01-28
JPS4881836A (US20110232667A1-20110929-C00004.png) 1973-11-01
AU452896B2 (en) 1974-08-30
JPS5253801A (en) 1977-04-30
IE37108B1 (en) 1977-05-11
IE37106L (en) 1973-07-26
IL49285A (en) 1977-10-31
GB1419181A (en) 1975-12-24
ES410962A1 (es) 1977-04-01
NL7708070A (nl) 1977-10-31
RO71588A (fr) 1982-02-26
JPS5333583B2 (US20110232667A1-20110929-C00004.png) 1978-09-14
FR2257567A1 (US20110232667A1-20110929-C00004.png) 1975-08-08
AR199893A1 (es) 1974-10-08
DE2365513B2 (de) 1978-11-16
CH590834A5 (US20110232667A1-20110929-C00004.png) 1977-08-31
FR2181693A1 (US20110232667A1-20110929-C00004.png) 1973-12-07
DE2365513C3 (de) 1979-07-19
SE7600889L (sv) 1976-01-28
FR2272642B1 (US20110232667A1-20110929-C00004.png) 1981-08-07
BG25208A3 (en) 1978-08-10
IE37106B1 (en) 1977-05-11
FR2257567B1 (US20110232667A1-20110929-C00004.png) 1978-02-03
ES438595A1 (es) 1977-06-16
CH580046A5 (US20110232667A1-20110929-C00004.png) 1976-09-30
BG25207A3 (en) 1978-08-10
IL41305A0 (en) 1973-03-30
NL153514B (nl) 1977-06-15
DD113214A5 (US20110232667A1-20110929-C00004.png) 1975-05-20
IL49286A (en) 1977-10-31
NL7301094A (US20110232667A1-20110929-C00004.png) 1973-07-30
JPS5253840A (en) 1977-04-30
IE37108L (en) 1973-07-26
IL49285A0 (en) 1976-05-31
ES438594A1 (es) 1977-10-16
BE794516A (fr) 1973-05-16
FR2272642A1 (US20110232667A1-20110929-C00004.png) 1975-12-26
AR200537A1 (es) 1974-11-15
DD112750A5 (US20110232667A1-20110929-C00004.png) 1975-05-05
DD108069A5 (US20110232667A1-20110929-C00004.png) 1974-09-05
SE7600888L (sv) 1976-01-28
DE2303612B2 (de) 1977-04-07
DE2303612A1 (de) 1973-10-25
DE2365927A1 (de) 1976-12-09
AU5108173A (en) 1974-07-18
CA1014092A (en) 1977-07-19

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