BG106961A - Phenylpiperazinyl derivatives - Google Patents
Phenylpiperazinyl derivativesInfo
- Publication number
- BG106961A BG106961A BG106961A BG10696102A BG106961A BG 106961 A BG106961 A BG 106961A BG 106961 A BG106961 A BG 106961A BG 10696102 A BG10696102 A BG 10696102A BG 106961 A BG106961 A BG 106961A
- Authority
- BG
- Bulgaria
- Prior art keywords
- derivatives
- phenylpiperazinyl derivatives
- phenylpiperazinyl
- alk
- dopamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199901886 | 1999-12-30 | ||
| PCT/DK2000/000720 WO2001049677A1 (en) | 1999-12-30 | 2000-12-20 | Phenylpiperazinyl derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG106961A true BG106961A (en) | 2003-04-30 |
Family
ID=8108810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG106961A BG106961A (en) | 1999-12-30 | 2002-07-26 | Phenylpiperazinyl derivatives |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20030083336A1 (es) |
| EP (1) | EP1246815B1 (es) |
| JP (1) | JP2003519223A (es) |
| KR (1) | KR20020067589A (es) |
| CN (1) | CN1437596A (es) |
| AR (1) | AR029217A1 (es) |
| AT (1) | ATE261958T1 (es) |
| AU (1) | AU2152001A (es) |
| BG (1) | BG106961A (es) |
| BR (1) | BR0016951A (es) |
| CA (1) | CA2395867A1 (es) |
| DE (1) | DE60009154D1 (es) |
| EA (1) | EA200200731A1 (es) |
| HU (1) | HUP0203645A3 (es) |
| IL (1) | IL150337A0 (es) |
| IS (1) | IS6431A (es) |
| MX (1) | MXPA02006499A (es) |
| NO (1) | NO20023149D0 (es) |
| NZ (1) | NZ519692A (es) |
| PL (1) | PL355540A1 (es) |
| SK (1) | SK11062002A3 (es) |
| TR (1) | TR200201684T2 (es) |
| WO (1) | WO2001049677A1 (es) |
| ZA (1) | ZA200204970B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040002488A1 (en) * | 2002-05-29 | 2004-01-01 | Cowart Marlon D. | Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction |
| EP1927594A1 (en) * | 2003-01-14 | 2008-06-04 | Arena Pharmaceuticals, Inc. | 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| US8293751B2 (en) * | 2003-01-14 | 2012-10-23 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| RS50589B (sr) | 2003-12-23 | 2010-05-07 | H. Lundbeck A/S. | 2-(1h-indolilsulfanil)-benzil amin derivati kao ssri |
| AR052308A1 (es) | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
| NZ555491A (en) * | 2005-01-03 | 2010-01-29 | Univ Siena | Aryl piperazine derivatives for the treatment of neuropsychiatric disorders |
| US7629473B2 (en) | 2005-06-17 | 2009-12-08 | H. Lundbeck A/S | 2-(1H-indolylsulfanyl)-aryl amine derivatives |
| KR100868353B1 (ko) * | 2007-03-08 | 2008-11-12 | 한국화학연구원 | 도파민 ｄ4 수용체 길항제인 신규 피페라지닐프로필피라졸유도체, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
| BR112013008100A2 (pt) | 2010-09-22 | 2016-08-09 | Arena Pharm Inc | "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles." |
| CN104725359B (zh) | 2013-12-20 | 2017-05-03 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
| CN105085482B (zh) * | 2014-05-04 | 2018-08-10 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
| CN105085491B (zh) * | 2014-05-05 | 2019-06-25 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| GB201416352D0 (en) | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Spirocyclic derivatives |
| GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
| CN105732591B (zh) * | 2014-12-31 | 2019-10-25 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
| CN116850181A (zh) | 2015-01-06 | 2023-10-10 | 艾尼纳制药公司 | 治疗与s1p1受体有关的病症的方法 |
| MX2017016530A (es) | 2015-06-22 | 2018-03-12 | Arena Pharm Inc | Sal cristalina de l-arginina del acido (r)-2-(7-(4-ciclopentil-3-( trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclopenta[b]indol-3- il)acetico (compuesto1) para ser utilizada en transtornos asociados con el receptor de esfingosina-1-fosfato 1 (s1p1). |
| CN106795160B (zh) * | 2015-07-23 | 2019-04-19 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| CN106795143B (zh) * | 2015-08-13 | 2019-05-24 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| CN110520124A (zh) | 2017-02-16 | 2019-11-29 | 艾尼纳制药公司 | 用于治疗原发性胆汁性胆管炎的化合物和方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| GB9305623D0 (en) * | 1993-03-18 | 1993-05-05 | Merck Sharp & Dohme | Therapeutic agents |
| GB9306578D0 (en) * | 1993-03-30 | 1993-05-26 | Merck Sharp & Dohme | Therapeutic agents |
| US5814644A (en) * | 1993-04-15 | 1998-09-29 | Merck Sharp & Dohme, Ltd. | Indole derivatives as dopamine D4 antagonists |
| WO1995029911A1 (en) * | 1994-04-28 | 1995-11-09 | Merck Sharp & Dohme Limited | Benzofuran derivatives as d4 receptor antagonists |
| ES2201105T3 (es) * | 1994-08-05 | 2004-03-16 | Pfizer Inc. | Derivados del bencimidazol con actividad dopaminergica. |
| USH2007H1 (en) * | 1996-01-19 | 2001-12-04 | Fmc Corporation | Insecticidal N-heterocyclylalkyl-or N-[(polycyclyl)alkyl]-N′substituted piperazines |
-
2000
- 2000-12-20 EA EA200200731A patent/EA200200731A1/ru unknown
- 2000-12-20 KR KR1020027008602A patent/KR20020067589A/ko not_active Application Discontinuation
- 2000-12-20 WO PCT/DK2000/000720 patent/WO2001049677A1/en not_active Application Discontinuation
- 2000-12-20 EP EP00984923A patent/EP1246815B1/en not_active Expired - Lifetime
- 2000-12-20 MX MXPA02006499A patent/MXPA02006499A/es unknown
- 2000-12-20 AT AT00984923T patent/ATE261958T1/de not_active IP Right Cessation
- 2000-12-20 PL PL00355540A patent/PL355540A1/xx not_active Application Discontinuation
- 2000-12-20 IL IL15033700A patent/IL150337A0/xx unknown
- 2000-12-20 BR BR0016951-0A patent/BR0016951A/pt not_active IP Right Cessation
- 2000-12-20 DE DE60009154T patent/DE60009154D1/de not_active Expired - Lifetime
- 2000-12-20 CA CA002395867A patent/CA2395867A1/en not_active Abandoned
- 2000-12-20 CN CN00819202A patent/CN1437596A/zh active Pending
- 2000-12-20 HU HU0203645A patent/HUP0203645A3/hu unknown
- 2000-12-20 NZ NZ519692A patent/NZ519692A/en not_active Application Discontinuation
- 2000-12-20 TR TR2002/01684T patent/TR200201684T2/xx unknown
- 2000-12-20 JP JP2001550217A patent/JP2003519223A/ja not_active Withdrawn
- 2000-12-20 AU AU21520/01A patent/AU2152001A/en not_active Abandoned
- 2000-12-20 SK SK1106-2002A patent/SK11062002A3/sk unknown
- 2000-12-28 AR ARP000106990A patent/AR029217A1/es not_active Application Discontinuation
-
2002
- 2002-06-19 IS IS6431A patent/IS6431A/is unknown
- 2002-06-20 ZA ZA200204970A patent/ZA200204970B/en unknown
- 2002-06-25 US US10/183,963 patent/US20030083336A1/en not_active Abandoned
- 2002-06-28 NO NO20023149A patent/NO20023149D0/no not_active Application Discontinuation
- 2002-07-26 BG BG106961A patent/BG106961A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL150337A0 (en) | 2002-12-01 |
| CN1437596A (zh) | 2003-08-20 |
| IS6431A (is) | 2002-06-19 |
| EP1246815B1 (en) | 2004-03-17 |
| AU2152001A (en) | 2001-07-16 |
| EA200200731A1 (ru) | 2002-12-26 |
| HUP0203645A2 (hu) | 2003-02-28 |
| JP2003519223A (ja) | 2003-06-17 |
| DE60009154D1 (de) | 2004-04-22 |
| AR029217A1 (es) | 2003-06-18 |
| PL355540A1 (en) | 2004-05-04 |
| ZA200204970B (en) | 2004-01-26 |
| MXPA02006499A (es) | 2002-11-29 |
| EP1246815A1 (en) | 2002-10-09 |
| KR20020067589A (ko) | 2002-08-22 |
| NO20023149L (no) | 2002-06-28 |
| SK11062002A3 (sk) | 2002-12-03 |
| TR200201684T2 (tr) | 2002-10-21 |
| BR0016951A (pt) | 2003-02-25 |
| ATE261958T1 (de) | 2004-04-15 |
| WO2001049677A1 (en) | 2001-07-12 |
| US20030083336A1 (en) | 2003-05-01 |
| HUP0203645A3 (en) | 2004-01-28 |
| NO20023149D0 (no) | 2002-06-28 |
| NZ519692A (en) | 2004-05-28 |
| CA2395867A1 (en) | 2001-07-12 |
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