BG106961A - Phenylpiperazinyl derivatives - Google Patents
Phenylpiperazinyl derivativesInfo
- Publication number
- BG106961A BG106961A BG106961A BG10696102A BG106961A BG 106961 A BG106961 A BG 106961A BG 106961 A BG106961 A BG 106961A BG 10696102 A BG10696102 A BG 10696102A BG 106961 A BG106961 A BG 106961A
- Authority
- BG
- Bulgaria
- Prior art keywords
- derivatives
- phenylpiperazinyl derivatives
- phenylpiperazinyl
- alk
- dopamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199901886 | 1999-12-30 | ||
| PCT/DK2000/000720 WO2001049677A1 (en) | 1999-12-30 | 2000-12-20 | Phenylpiperazinyl derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG106961A true BG106961A (en) | 2003-04-30 |
Family
ID=8108810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG106961A BG106961A (en) | 1999-12-30 | 2002-07-26 | Phenylpiperazinyl derivatives |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20030083336A1 (es) |
| EP (1) | EP1246815B1 (es) |
| JP (1) | JP2003519223A (es) |
| KR (1) | KR20020067589A (es) |
| CN (1) | CN1437596A (es) |
| AR (1) | AR029217A1 (es) |
| AT (1) | ATE261958T1 (es) |
| AU (1) | AU2152001A (es) |
| BG (1) | BG106961A (es) |
| BR (1) | BR0016951A (es) |
| CA (1) | CA2395867A1 (es) |
| DE (1) | DE60009154D1 (es) |
| EA (1) | EA200200731A1 (es) |
| HU (1) | HUP0203645A3 (es) |
| IL (1) | IL150337A0 (es) |
| IS (1) | IS6431A (es) |
| MX (1) | MXPA02006499A (es) |
| NO (1) | NO20023149D0 (es) |
| NZ (1) | NZ519692A (es) |
| PL (1) | PL355540A1 (es) |
| SK (1) | SK11062002A3 (es) |
| TR (1) | TR200201684T2 (es) |
| WO (1) | WO2001049677A1 (es) |
| ZA (1) | ZA200204970B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040002488A1 (en) * | 2002-05-29 | 2004-01-01 | Cowart Marlon D. | Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction |
| EA011009B1 (ru) * | 2003-01-14 | 2008-12-30 | Арена Фармасьютикалз Инк. | 1,2,3-тризамещённые арильные и гетероарильные производные в качестве модуляторов метаболизма и профилактика и лечение расстройств, связанных с ним, таких как диабет и гипергликемия |
| EP1927594A1 (en) * | 2003-01-14 | 2008-06-04 | Arena Pharmaceuticals, Inc. | 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| PL1701940T3 (pl) | 2003-12-23 | 2008-11-28 | H Lundbeck As | Pochodne 2-(1H-indolilosulfanylo)benzyloaminy jako SSRI |
| AR052308A1 (es) | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
| AU2006204522A1 (en) * | 2005-01-03 | 2006-07-13 | Universita Degli Studi Di Siena | Aryl piperazine derivatives for the treatment of neuropsychiatric disorders |
| US7629473B2 (en) | 2005-06-17 | 2009-12-08 | H. Lundbeck A/S | 2-(1H-indolylsulfanyl)-aryl amine derivatives |
| KR100868353B1 (ko) * | 2007-03-08 | 2008-11-12 | 한국화학연구원 | 도파민 ｄ4 수용체 길항제인 신규 피페라지닐프로필피라졸유도체, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
| WO2012040279A1 (en) | 2010-09-22 | 2012-03-29 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| EP3083589B1 (en) | 2013-12-20 | 2019-12-18 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods of use thereof |
| WO2015169180A1 (en) * | 2014-05-04 | 2015-11-12 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods and use thereof |
| CN105085491B (zh) * | 2014-05-05 | 2019-06-25 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
| GB201416352D0 (en) | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Spirocyclic derivatives |
| CN105732591B (zh) * | 2014-12-31 | 2019-10-25 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
| MX2021011472A (es) | 2015-01-06 | 2022-08-17 | Arena Pharm Inc | Metodos de condiciones de tratamiento relacionadas con el receptor s1p1. |
| US10301262B2 (en) | 2015-06-22 | 2019-05-28 | Arena Pharmaceuticals, Inc. | Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compund1) for use in SIPI receptor-associated disorders |
| CN106795160B (zh) * | 2015-07-23 | 2019-04-19 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| WO2017025058A1 (zh) * | 2015-08-13 | 2017-02-16 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| MX2019009841A (es) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compuestos y metodos para el tratamiento de la colangitis biliar primaria. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| GB9305623D0 (en) * | 1993-03-18 | 1993-05-05 | Merck Sharp & Dohme | Therapeutic agents |
| GB9306578D0 (en) * | 1993-03-30 | 1993-05-26 | Merck Sharp & Dohme | Therapeutic agents |
| WO1994024105A1 (en) * | 1993-04-15 | 1994-10-27 | Merck Sharp & Dohme Limited | Indole derivatives as dopamine d4 antagonists |
| EP0757686A1 (en) * | 1994-04-28 | 1997-02-12 | MERCK SHARP & DOHME LTD. | Benzofuran derivatives as d 4? receptor antagonists |
| PT775118E (pt) * | 1994-08-05 | 2003-10-31 | Pfizer | Derivados de benzimidazole com actividade dopaminergica |
| USH2007H1 (en) * | 1996-01-19 | 2001-12-04 | Fmc Corporation | Insecticidal N-heterocyclylalkyl-or N-[(polycyclyl)alkyl]-N′substituted piperazines |
-
2000
- 2000-12-20 DE DE60009154T patent/DE60009154D1/de not_active Expired - Lifetime
- 2000-12-20 CA CA002395867A patent/CA2395867A1/en not_active Abandoned
- 2000-12-20 AU AU21520/01A patent/AU2152001A/en not_active Abandoned
- 2000-12-20 TR TR2002/01684T patent/TR200201684T2/xx unknown
- 2000-12-20 JP JP2001550217A patent/JP2003519223A/ja not_active Withdrawn
- 2000-12-20 AT AT00984923T patent/ATE261958T1/de not_active IP Right Cessation
- 2000-12-20 NZ NZ519692A patent/NZ519692A/en not_active Application Discontinuation
- 2000-12-20 CN CN00819202A patent/CN1437596A/zh active Pending
- 2000-12-20 MX MXPA02006499A patent/MXPA02006499A/es unknown
- 2000-12-20 PL PL00355540A patent/PL355540A1/xx not_active Application Discontinuation
- 2000-12-20 WO PCT/DK2000/000720 patent/WO2001049677A1/en not_active Application Discontinuation
- 2000-12-20 HU HU0203645A patent/HUP0203645A3/hu unknown
- 2000-12-20 BR BR0016951-0A patent/BR0016951A/pt not_active IP Right Cessation
- 2000-12-20 KR KR1020027008602A patent/KR20020067589A/ko not_active Application Discontinuation
- 2000-12-20 EP EP00984923A patent/EP1246815B1/en not_active Expired - Lifetime
- 2000-12-20 SK SK1106-2002A patent/SK11062002A3/sk unknown
- 2000-12-20 IL IL15033700A patent/IL150337A0/xx unknown
- 2000-12-20 EA EA200200731A patent/EA200200731A1/ru unknown
- 2000-12-28 AR ARP000106990A patent/AR029217A1/es not_active Application Discontinuation
-
2002
- 2002-06-19 IS IS6431A patent/IS6431A/is unknown
- 2002-06-20 ZA ZA200204970A patent/ZA200204970B/en unknown
- 2002-06-25 US US10/183,963 patent/US20030083336A1/en not_active Abandoned
- 2002-06-28 NO NO20023149A patent/NO20023149D0/no not_active Application Discontinuation
- 2002-07-26 BG BG106961A patent/BG106961A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200204970B (en) | 2004-01-26 |
| IS6431A (is) | 2002-06-19 |
| HUP0203645A2 (hu) | 2003-02-28 |
| EA200200731A1 (ru) | 2002-12-26 |
| NO20023149L (no) | 2002-06-28 |
| CA2395867A1 (en) | 2001-07-12 |
| PL355540A1 (en) | 2004-05-04 |
| CN1437596A (zh) | 2003-08-20 |
| IL150337A0 (en) | 2002-12-01 |
| TR200201684T2 (tr) | 2002-10-21 |
| NZ519692A (en) | 2004-05-28 |
| AU2152001A (en) | 2001-07-16 |
| DE60009154D1 (de) | 2004-04-22 |
| SK11062002A3 (sk) | 2002-12-03 |
| AR029217A1 (es) | 2003-06-18 |
| MXPA02006499A (es) | 2002-11-29 |
| US20030083336A1 (en) | 2003-05-01 |
| JP2003519223A (ja) | 2003-06-17 |
| HUP0203645A3 (en) | 2004-01-28 |
| EP1246815B1 (en) | 2004-03-17 |
| NO20023149D0 (no) | 2002-06-28 |
| WO2001049677A1 (en) | 2001-07-12 |
| ATE261958T1 (de) | 2004-04-15 |
| EP1246815A1 (en) | 2002-10-09 |
| KR20020067589A (ko) | 2002-08-22 |
| BR0016951A (pt) | 2003-02-25 |
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