BG106816A - Cyclic quaternary ammonium compounds - Google Patents
Cyclic quaternary ammonium compoundsInfo
- Publication number
- BG106816A BG106816A BG106816A BG10681602A BG106816A BG 106816 A BG106816 A BG 106816A BG 106816 A BG106816 A BG 106816A BG 10681602 A BG10681602 A BG 10681602A BG 106816 A BG106816 A BG 106816A
- Authority
- BG
- Bulgaria
- Prior art keywords
- quaternary ammonium
- ammonium compounds
- cyclic quaternary
- formula
- compounds
- Prior art date
Links
- -1 Cyclic quaternary ammonium compounds Chemical class 0.000 title abstract 2
- 206010011224 Cough Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2292351 | 1999-12-15 | ||
| PCT/CA2000/001506 WO2001044192A1 (en) | 1999-12-15 | 2000-12-15 | Cyclic quaternary ammonium compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG106816A true BG106816A (en) | 2003-04-30 |
Family
ID=4164887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG106816A BG106816A (en) | 1999-12-15 | 2002-06-12 | Cyclic quaternary ammonium compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20030166629A1 (cs) |
| EP (1) | EP1278731A1 (cs) |
| JP (1) | JP2003516966A (cs) |
| KR (1) | KR20020074170A (cs) |
| CN (1) | CN1425005A (cs) |
| AU (1) | AU2334501A (cs) |
| BG (1) | BG106816A (cs) |
| BR (1) | BR0016431A (cs) |
| CZ (1) | CZ20022095A3 (cs) |
| EE (1) | EE200200314A (cs) |
| HU (1) | HUP0301686A2 (cs) |
| IL (1) | IL150179A0 (cs) |
| IS (1) | IS6417A (cs) |
| MX (1) | MXPA02006051A (cs) |
| NO (1) | NO20022870L (cs) |
| PL (1) | PL356032A1 (cs) |
| WO (1) | WO2001044192A1 (cs) |
| YU (1) | YU44102A (cs) |
| ZA (1) | ZA200205566B (cs) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010510227A (ja) | 2006-11-20 | 2010-04-02 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 痛みおよび痒みの治療方法、組成物およびキット |
| AU2009223739A1 (en) * | 2008-03-11 | 2009-09-17 | President And Fellows Of Harvard College | Methods, compositions, and kits for treating pain and pruritis |
| CA3027255C (en) * | 2009-07-10 | 2022-06-21 | The General Hospital Corporation | Permanently charged sodium and calcium channel blockers as anti-inflammatory agents |
| WO2014085154A1 (en) | 2012-11-27 | 2014-06-05 | Beth Israel Deaconess Medical Center, Inc. | Methods for treating renal disease |
| WO2015120069A1 (en) | 2014-02-04 | 2015-08-13 | Beth Israel Deaconess Medical Center, Inc. | Methods and kits for the diagnosis and treatment of pancreatic cancer |
| CA2994545A1 (en) * | 2015-08-03 | 2017-02-09 | President And Fellows Of Harvard College | Charged ion channel blockers and methods for use |
| MA55318A (fr) | 2019-03-11 | 2022-01-19 | Nocion Therapeutics Inc | Bloqueurs de canaux ioniques chargés et procédés d'utilisation |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CN113795248A (zh) | 2019-03-11 | 2021-12-14 | 诺西恩医疗公司 | 带电荷的离子通道阻滞剂及其使用方法 |
| US10828287B2 (en) | 2019-03-11 | 2020-11-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| WO2020185915A1 (en) | 2019-03-11 | 2020-09-17 | Nocion Therapeutics, Inc. | Ester substituted ion channel blockers and methods for use |
| CN114828845A (zh) | 2019-11-06 | 2022-07-29 | 诺西恩医疗公司 | 带电的离子通道阻滞剂及其使用方法 |
| EP4054586A4 (en) | 2019-11-06 | 2023-11-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP7708777B2 (ja) | 2020-03-11 | 2025-07-15 | ノシオン セラピューティクス，インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI58632C (fi) * | 1978-02-07 | 1981-03-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av anilider med antitussiv verkan |
-
2000
- 2000-12-15 CZ CZ20022095A patent/CZ20022095A3/cs unknown
- 2000-12-15 WO PCT/CA2000/001506 patent/WO2001044192A1/en not_active Application Discontinuation
- 2000-12-15 BR BR0016431-3A patent/BR0016431A/pt not_active IP Right Cessation
- 2000-12-15 PL PL00356032A patent/PL356032A1/xx not_active Application Discontinuation
- 2000-12-15 JP JP2001544682A patent/JP2003516966A/ja active Pending
- 2000-12-15 AU AU23345/01A patent/AU2334501A/en not_active Abandoned
- 2000-12-15 MX MXPA02006051A patent/MXPA02006051A/es unknown
- 2000-12-15 CN CN00818470A patent/CN1425005A/zh active Pending
- 2000-12-15 KR KR1020027007713A patent/KR20020074170A/ko not_active Withdrawn
- 2000-12-15 EP EP00986917A patent/EP1278731A1/en not_active Withdrawn
- 2000-12-15 EE EEP200200314A patent/EE200200314A/xx unknown
- 2000-12-15 HU HU0301686A patent/HUP0301686A2/hu unknown
- 2000-12-15 US US10/149,666 patent/US20030166629A1/en not_active Abandoned
- 2000-12-15 YU YU44102A patent/YU44102A/sh unknown
- 2000-12-15 IL IL15017900A patent/IL150179A0/xx unknown
-
2002
- 2002-06-12 IS IS6417A patent/IS6417A/is unknown
- 2002-06-12 BG BG106816A patent/BG106816A/xx unknown
- 2002-06-14 NO NO20022870A patent/NO20022870L/no not_active Application Discontinuation
- 2002-07-11 ZA ZA200205566A patent/ZA200205566B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020074170A (ko) | 2002-09-28 |
| WO2001044192A1 (en) | 2001-06-21 |
| EE200200314A (et) | 2003-08-15 |
| IS6417A (is) | 2002-06-12 |
| EP1278731A1 (en) | 2003-01-29 |
| NO20022870L (no) | 2002-08-14 |
| ZA200205566B (en) | 2003-11-17 |
| MXPA02006051A (es) | 2004-08-23 |
| JP2003516966A (ja) | 2003-05-20 |
| US20030166629A1 (en) | 2003-09-04 |
| CN1425005A (zh) | 2003-06-18 |
| BR0016431A (pt) | 2002-10-01 |
| NO20022870D0 (no) | 2002-06-14 |
| IL150179A0 (en) | 2002-12-01 |
| YU44102A (sh) | 2005-09-19 |
| PL356032A1 (en) | 2004-06-14 |
| HUP0301686A2 (hu) | 2003-08-28 |
| CZ20022095A3 (cs) | 2003-02-12 |
| AU2334501A (en) | 2001-06-25 |
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