BG106414A - Биодостъпна дозирана форма на изотретиноин - Google Patents

Биодостъпна дозирана форма на изотретиноин

Info

Publication number
BG106414A
BG106414A BG06414A BG10641402A BG106414A BG 106414 A BG106414 A BG 106414A BG 06414 A BG06414 A BG 06414A BG 10641402 A BG10641402 A BG 10641402A BG 106414 A BG106414 A BG 106414A
Authority
BG
Bulgaria
Prior art keywords
isotretinoin
dosage form
cis
bioavailable
bioavailable dosage
Prior art date
Application number
BG06414A
Other languages
English (en)
Inventor
Abha Pant
Inderdeep Bhatia
Sunilendu ROY
Rajiv Malik
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of BG106414A publication Critical patent/BG106414A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретението се отнася до биодостъпен фармацевтичен състав на 13-бис витамин А киселина, известна също като 13-цис ретинова киселина и изотретиноин,и до метод за получаването му. 13-цис витамин А киселината е относително водонеразтворимо съединение, което се разпада, когато се изложи на светлина и атмосферен кислород. Лекарственото средство е в стабилна и предсказуемо биодостъпна дозирана форма.
BG06414A 2000-06-16 2002-02-14 Биодостъпна дозирана форма на изотретиноин BG106414A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN596DE2000 IN192188B (bg) 2000-06-16 2000-06-16
PCT/IB2001/000581 WO2001095886A1 (en) 2000-06-16 2001-04-09 Bioavailable dosage form of isotretinoin

Publications (1)

Publication Number Publication Date
BG106414A true BG106414A (bg) 2002-09-30

Family

ID=11097063

Family Applications (1)

Application Number Title Priority Date Filing Date
BG06414A BG106414A (bg) 2000-06-16 2002-02-14 Биодостъпна дозирана форма на изотретиноин

Country Status (25)

Country Link
US (1) US6740337B2 (bg)
EP (1) EP1294357A1 (bg)
JP (1) JP2004503493A (bg)
CN (1) CN1196475C (bg)
AP (1) AP2002002423A0 (bg)
AU (1) AU782094B2 (bg)
BG (1) BG106414A (bg)
BR (1) BR0106752A (bg)
CA (1) CA2382065A1 (bg)
CZ (1) CZ2002694A3 (bg)
EA (1) EA004808B1 (bg)
EE (1) EE200200074A (bg)
HK (1) HK1052302A1 (bg)
HR (1) HRP20020148A2 (bg)
HU (1) HUP0203717A3 (bg)
IL (1) IL148176A0 (bg)
IN (1) IN192188B (bg)
MX (1) MXPA02001669A (bg)
NZ (1) NZ517142A (bg)
OA (1) OA12008A (bg)
PL (1) PL352838A1 (bg)
SK (1) SK2252002A3 (bg)
UA (1) UA74793C2 (bg)
WO (1) WO2001095886A1 (bg)
ZA (1) ZA200201240B (bg)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1318791B1 (en) * 2000-09-22 2004-07-07 Galephar M/F Pharmaceutical semi-solid composition of isotretinoin
EP1527774A1 (en) 2003-11-03 2005-05-04 Basilea Pharmaceutica AG New formulation for retinoid-containing soft gelatin capsules
WO2004103346A1 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Pharmaceutical compositions of acitretin
US20070254025A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Oral contraceptive and acne medication combination and treatment of acne with reduced side effects
US20070254858A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects
CN101610754A (zh) * 2007-02-16 2009-12-23 Aska制药株式会社 含有微粒油性混悬液的药物组合物
WO2008102375A2 (en) * 2007-02-20 2008-08-28 Ipca Laboratories Limited A process for preparation of highly pure isotretinoin
US9078925B2 (en) 2012-06-18 2015-07-14 Galephar Pharmaceutical Research, Inc. Pharmaceutical semi-solid composition of isotretinoin
WO2016189481A1 (en) * 2015-05-25 2016-12-01 Sun Pharmaceutical Industries Limited Once daily oral pharmaceutical composition of isotretinoin
US10517846B2 (en) 2016-05-26 2019-12-31 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for treating acne

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016254A (en) * 1972-05-19 1977-04-05 Beecham Group Limited Pharmaceutical formulations
CA1282326C (en) * 1984-12-14 1991-04-02 Paul J. Jarosz Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient
US4808630A (en) 1987-01-16 1989-02-28 United States Of America Method of treating psychotic illnesses
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
PE20001227A1 (es) * 1998-10-30 2000-11-06 Hoffmann La Roche Procesos para producir una composicion de isotretinoina
US6284283B1 (en) * 1999-10-21 2001-09-04 Alkermes Controlled Therapeutics, Inc. Method of producing sub-micron particles of biologically active agents and uses thereof

Also Published As

Publication number Publication date
EE200200074A (et) 2003-04-15
HUP0203717A2 (hu) 2003-04-28
IN192188B (bg) 2004-03-13
PL352838A1 (en) 2003-09-08
CN1196475C (zh) 2005-04-13
AP2002002423A0 (en) 2002-03-31
MXPA02001669A (es) 2002-08-06
HRP20020148A2 (en) 2003-12-31
NZ517142A (en) 2003-08-29
CZ2002694A3 (cs) 2002-08-14
IL148176A0 (en) 2002-09-12
US6740337B2 (en) 2004-05-25
JP2004503493A (ja) 2004-02-05
OA12008A (en) 2006-04-19
AU782094B2 (en) 2005-06-30
UA74793C2 (en) 2006-02-15
US20020025338A1 (en) 2002-02-28
CN1388757A (zh) 2003-01-01
EP1294357A1 (en) 2003-03-26
ZA200201240B (en) 2002-09-02
HUP0203717A3 (en) 2003-05-28
WO2001095886A1 (en) 2001-12-20
BR0106752A (pt) 2002-04-16
SK2252002A3 (en) 2002-08-06
CA2382065A1 (en) 2001-12-20
AU4445901A (en) 2001-12-24
EA004808B1 (ru) 2004-08-26
EA200200166A1 (ru) 2002-10-31
HK1052302A1 (zh) 2003-09-11

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