BG105196A - New 4-amino-1-aryl-pyridine-2-ones with anticonvulsive action and methods for producing same - Google Patents
New 4-amino-1-aryl-pyridine-2-ones with anticonvulsive action and methods for producing sameInfo
- Publication number
- BG105196A BG105196A BG105196A BG10519601A BG105196A BG 105196 A BG105196 A BG 105196A BG 105196 A BG105196 A BG 105196A BG 10519601 A BG10519601 A BG 10519601A BG 105196 A BG105196 A BG 105196A
- Authority
- BG
- Bulgaria
- Prior art keywords
- amino
- pyridine
- aryl
- ones
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19835918A DE19835918A1 (de) | 1998-08-07 | 1998-08-07 | Neue antikonvulsiv wirkende 4-Amino-1-aryl-pyridin-2-one und Verfahren zu deren Herstellung |
| PCT/EP1999/005399 WO2000007988A1 (de) | 1998-08-07 | 1999-07-28 | Neue, antikonvulsiv wirkende 4-amino-1-aryl-pyridin-2-one und verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG105196A true BG105196A (en) | 2001-12-29 |
Family
ID=7876889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG105196A BG105196A (en) | 1998-08-07 | 2001-01-30 | New 4-amino-1-aryl-pyridine-2-ones with anticonvulsive action and methods for producing same |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6071911A (xx) |
| EP (1) | EP1102748A1 (xx) |
| JP (1) | JP2002522420A (xx) |
| KR (1) | KR20010074802A (xx) |
| CN (1) | CN1322197A (xx) |
| AR (1) | AR021186A1 (xx) |
| AU (1) | AU5507499A (xx) |
| BG (1) | BG105196A (xx) |
| BR (1) | BR9912849A (xx) |
| CA (1) | CA2279692C (xx) |
| DE (1) | DE19835918A1 (xx) |
| HU (1) | HUP0103204A3 (xx) |
| IL (1) | IL141200A0 (xx) |
| NO (1) | NO20010575L (xx) |
| NZ (1) | NZ509914A (xx) |
| PL (1) | PL346013A1 (xx) |
| RU (1) | RU2001106634A (xx) |
| SK (1) | SK2002001A3 (xx) |
| TR (1) | TR200100370T2 (xx) |
| WO (1) | WO2000007988A1 (xx) |
| ZA (1) | ZA200100999B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ522773A (en) | 2000-06-12 | 2005-06-24 | Eisai Co Ltd | 1,2-dihydropyridine compounds, manufacturing method thereof and use thereof |
| GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
| MY148809A (en) | 2004-07-06 | 2013-05-31 | Eisai R&D Man Co Ltd | Crystals of 1,2-dihydropyridine compound and their production process |
| WO2020124090A1 (en) | 2018-12-14 | 2020-06-18 | Eisai R&D Management Co., Ltd. | Aqueous based pharmaceutical formulations of 1,2-dihydropyridine compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51118768A (en) * | 1975-02-19 | 1976-10-18 | Shigeo Senda | Method for preparing 4-amino-2-pyridone derivatives |
| ATE25078T1 (de) * | 1982-10-27 | 1987-02-15 | Degussa | 2-amino-3-acylamino-6-benzylamino-pyridinderivate mit anti-epileptischer wirkung. |
-
1998
- 1998-08-07 DE DE19835918A patent/DE19835918A1/de not_active Withdrawn
-
1999
- 1999-07-28 CN CN99811849A patent/CN1322197A/zh active Pending
- 1999-07-28 AU AU55074/99A patent/AU5507499A/en not_active Abandoned
- 1999-07-28 NZ NZ509914A patent/NZ509914A/xx unknown
- 1999-07-28 WO PCT/EP1999/005399 patent/WO2000007988A1/de not_active Application Discontinuation
- 1999-07-28 RU RU2001106634/04A patent/RU2001106634A/ru unknown
- 1999-07-28 EP EP99941472A patent/EP1102748A1/de not_active Withdrawn
- 1999-07-28 JP JP2000563622A patent/JP2002522420A/ja active Pending
- 1999-07-28 IL IL14120099A patent/IL141200A0/xx unknown
- 1999-07-28 BR BR9912849-7A patent/BR9912849A/pt not_active IP Right Cessation
- 1999-07-28 TR TR2001/00370T patent/TR200100370T2/xx unknown
- 1999-07-28 KR KR1020017001574A patent/KR20010074802A/ko not_active Application Discontinuation
- 1999-07-28 PL PL99346013A patent/PL346013A1/xx unknown
- 1999-07-28 HU HU0103204A patent/HUP0103204A3/hu unknown
- 1999-07-28 SK SK200-2001A patent/SK2002001A3/sk unknown
- 1999-08-05 CA CA002279692A patent/CA2279692C/en not_active Expired - Fee Related
- 1999-08-06 US US09/370,640 patent/US6071911A/en not_active Expired - Fee Related
- 1999-08-06 AR ARP990103952A patent/AR021186A1/es not_active Application Discontinuation
-
2001
- 2001-01-30 BG BG105196A patent/BG105196A/xx unknown
- 2001-02-02 NO NO20010575A patent/NO20010575L/no unknown
- 2001-02-06 ZA ZA200100999A patent/ZA200100999B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2279692C (en) | 2003-10-07 |
| PL346013A1 (en) | 2002-01-14 |
| TR200100370T2 (tr) | 2001-08-21 |
| US6071911A (en) | 2000-06-06 |
| WO2000007988A1 (de) | 2000-02-17 |
| ZA200100999B (en) | 2001-12-14 |
| AU5507499A (en) | 2000-02-28 |
| DE19835918A1 (de) | 2000-02-10 |
| NO20010575D0 (no) | 2001-02-02 |
| AR021186A1 (es) | 2002-07-03 |
| SK2002001A3 (en) | 2002-01-07 |
| RU2001106634A (ru) | 2004-02-27 |
| NO20010575L (no) | 2001-04-04 |
| CA2279692A1 (en) | 2000-02-07 |
| KR20010074802A (ko) | 2001-08-09 |
| IL141200A0 (en) | 2002-02-10 |
| BR9912849A (pt) | 2001-05-08 |
| HUP0103204A3 (en) | 2002-06-28 |
| HUP0103204A2 (hu) | 2002-04-29 |
| JP2002522420A (ja) | 2002-07-23 |
| NZ509914A (en) | 2002-11-26 |
| CN1322197A (zh) | 2001-11-14 |
| EP1102748A1 (de) | 2001-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TNSN04082A1 (en) | N,n'-substituted-1,3-diamino-2-hydroxypropane derivatives | |
| FR2706767B1 (xx) | ||
| GR3036675T3 (en) | Piperazino derivatives as neurokinin antagonists | |
| AU5426699A (en) | Phosphohalohydrins, method for making same and uses | |
| HK1068274A1 (en) | Use of 1-phenyl-3-dimethylaminopropane compounds for treating urinary incontinence | |
| PL346686A1 (en) | Method of catalitically nitrating aromatic compounds and application thereof | |
| DE50305587D1 (en) | 2-heteroarylcarbonsäureamide | |
| DK0989973T3 (da) | Chalconer med antiproliferativ aktivitet | |
| BG105196A (en) | New 4-amino-1-aryl-pyridine-2-ones with anticonvulsive action and methods for producing same | |
| ME00606B (me) | Postupak za pripremanje n,n’-bis[2,3-dihidroksipropil]–5- [(hidroksiacetil)metilamino]-2,4,6-trijodo-1,3-benzendikarboksamida | |
| HK1020722A1 (en) | Process for iohexol manufacture | |
| ZA964186B (en) | Cobalt metal agglomerates process for the production thereof and use thereof | |
| MXPA03008837A (es) | Una composicion farmaceutica estable de pravastatina. | |
| ZA200308012B (en) | Method of producing n-substituted 2,6-dialkyl morpholines | |
| AU2002310949A1 (en) | Method of producing N-substituted 2,6-dialkyl morpholines | |
| MXPA04004526A (es) | N-metil-homocisteinas, su uso y metodo para su produccion. | |
| PT973723E (pt) | Processo para a preparacao de um aminoalcool | |
| AU2001282832A1 (en) | New use of quetiapine | |
| MY119688A (en) | Use of arylguanidinium xanthogenates as vulcanization accelerators and process for the production thereof | |
| MXPA02010837A (es) | Compuestos derivados del felbamato. | |
| MY111508A (en) | Process for the production of c-substituted diethylenetriamines | |
| MXPA00006059A (es) | Mutantes del il-16, procesos para su produccion y su uso. | |
| HU9500321D0 (en) | Process for the preparation of 2,2'-dimorpholino-diethylether by reducing, catalytic amination of diethyleneglycol by morpholine | |
| MXPA05011854A (es) | Metodo para la produccion de fumarato de rac-1-{4- [2-hidroxi -3-(5-quinoliloxi) propil]-piperacin -1-il}2, 2-difeniletan-1 -ona purisimo y fumarato de rac-1-{4-[2- hidroxi-3 -(5-quinoliloxi) propil] piperacin-1-il} -2, 2-difeniletan -1-ona purisimo. | |
| MX9705390A (es) | Uso de los 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis de desordenes degenerativos cerebrales. |