BG103631A - 2-aminosubstituted pyridines applied for the treatment of atherosclerosis and hyperlipoproteinaemia - Google Patents

2-aminosubstituted pyridines applied for the treatment of atherosclerosis and hyperlipoproteinaemia

Info

Publication number
BG103631A
BG103631A BG103631A BG10363199A BG103631A BG 103631 A BG103631 A BG 103631A BG 103631 A BG103631 A BG 103631A BG 10363199 A BG10363199 A BG 10363199A BG 103631 A BG103631 A BG 103631A
Authority
BG
Bulgaria
Prior art keywords
aminosubstituted
pyridines
atherosclerosis
treatment
hyperlipoproteinaemia
Prior art date
Application number
BG103631A
Other languages
Bulgarian (bg)
English (en)
Inventor
Carsten Schmeck
Arndt Brandes
Michael Loegers
Guenter Schmidt
Klaus-Dieter Bremm
Hilmar Bischoff
Delf Schmidt
Joachim Schuhmacher
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG103631A publication Critical patent/BG103631A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
BG103631A 1997-02-05 1999-08-03 2-aminosubstituted pyridines applied for the treatment of atherosclerosis and hyperlipoproteinaemia BG103631A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19704243A DE19704243A1 (de) 1997-02-05 1997-02-05 Neue 2-Amino-substituierte Pyridine
PCT/EP1998/000362 WO1998034920A1 (de) 1997-02-05 1998-01-23 2-amino-substituierte pyridine verwendbar zur behandlung von arteriosklerose und hyperlipoproteinemie

Publications (1)

Publication Number Publication Date
BG103631A true BG103631A (en) 2000-11-30

Family

ID=7819326

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103631A BG103631A (en) 1997-02-05 1999-08-03 2-aminosubstituted pyridines applied for the treatment of atherosclerosis and hyperlipoproteinaemia

Country Status (19)

Country Link
EP (1) EP0973744A1 (cs)
JP (1) JP2001510478A (cs)
KR (1) KR20000070756A (cs)
CN (1) CN1252057A (cs)
AU (1) AU730109B2 (cs)
BG (1) BG103631A (cs)
BR (1) BR9807181A (cs)
CA (1) CA2279636A1 (cs)
CZ (1) CZ279299A3 (cs)
DE (1) DE19704243A1 (cs)
HU (1) HUP0001022A2 (cs)
ID (1) ID24208A (cs)
IL (1) IL131127A0 (cs)
NO (1) NO993738L (cs)
NZ (1) NZ337011A (cs)
PL (1) PL334899A1 (cs)
SK (1) SK104099A3 (cs)
TR (1) TR199901857T2 (cs)
WO (1) WO1998034920A1 (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA006777B1 (ru) 2001-06-22 2006-04-28 Пфайзер Продактс Инк. Фармацевтические композиции адсорбатов аморфного лекарственного средства
BR0210518A (pt) 2001-06-22 2004-06-22 Pfizer Prod Inc Composições farmacêuticas de dispersões de drogas e polìmeros neutros
EP1469832B2 (en) 2002-02-01 2016-10-26 Bend Research, Inc. Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
EP1603554A1 (en) 2003-03-17 2005-12-14 Japan Tobacco Inc. Method for increasing the oral bioavailability of s-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]-2-methylpropanethioate
CA2532931A1 (en) 2003-08-04 2005-02-10 Pfizer Products Inc. Pharmaceutical compositions of adsorbates of amorphous drugs and lipophilic microphase-forming materials
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
EP1670446A2 (en) 2003-09-26 2006-06-21 Japan Tobacco Inc. Method of inhibiting remnant lipoprotein production
DOP2005000123A (es) * 2004-07-02 2011-07-15 Merck Sharp & Dohme Inhibidores de cetp
WO2006032987A1 (en) * 2004-09-23 2006-03-30 Pfizer Products Inc. Indoline compounds and their use in the treatment of arteriosclerosis
EP1844078B1 (en) 2005-02-03 2016-09-28 Bend Research, Inc Pharmaceutical compositions with enhanced performance
US20100113473A1 (en) 2008-10-30 2010-05-06 Player Mark R Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169857A (en) * 1988-01-20 1992-12-08 Bayer Aktiengesellschaft 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis

Also Published As

Publication number Publication date
NZ337011A (en) 2001-04-27
SK104099A3 (en) 2000-01-18
ID24208A (id) 2000-07-13
EP0973744A1 (de) 2000-01-26
IL131127A0 (en) 2001-01-28
NO993738L (no) 1999-09-17
AU6212398A (en) 1998-08-26
PL334899A1 (en) 2000-03-27
WO1998034920A1 (de) 1998-08-13
BR9807181A (pt) 2000-01-25
NO993738D0 (no) 1999-08-02
JP2001510478A (ja) 2001-07-31
CA2279636A1 (en) 1998-08-13
CZ279299A3 (cs) 1999-11-17
AU730109B2 (en) 2001-02-22
CN1252057A (zh) 2000-05-03
TR199901857T2 (xx) 1999-10-21
DE19704243A1 (de) 1998-08-06
HUP0001022A2 (hu) 2000-09-28
KR20000070756A (ko) 2000-11-25

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