AU6212398A - 2-amino-substituted pyridines which can be used for the treatment of arteriosclerosis and hyperclipoproteinaemia - Google Patents

2-amino-substituted pyridines which can be used for the treatment of arteriosclerosis and hyperclipoproteinaemia

Info

Publication number
AU6212398A
AU6212398A AU62123/98A AU6212398A AU6212398A AU 6212398 A AU6212398 A AU 6212398A AU 62123/98 A AU62123/98 A AU 62123/98A AU 6212398 A AU6212398 A AU 6212398A AU 6212398 A AU6212398 A AU 6212398A
Authority
AU
Australia
Prior art keywords
hyperclipoproteinaemia
arteriosclerosis
amino
treatment
substituted pyridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU62123/98A
Other versions
AU730109B2 (en
Inventor
Hilmar Bischoff
Arndt Brandes
Klaus-Dieter Bremm
Michael Logers
Carsten Schmeck
Delf Schmidt
Gunter Schmidt
Joachim Schuhmacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU6212398A publication Critical patent/AU6212398A/en
Application granted granted Critical
Publication of AU730109B2 publication Critical patent/AU730109B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU62123/98A 1997-02-05 1998-01-23 2-amino-substituted pyridines which can be used for the treatment of arteriosclerosis and hyperclipoproteinaemia Ceased AU730109B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19704243 1997-02-05
DE19704243A DE19704243A1 (en) 1997-02-05 1997-02-05 New 2-amino-substituted pyridines
PCT/EP1998/000362 WO1998034920A1 (en) 1997-02-05 1998-01-23 2-amino substituted pyridines for use in the treatment of arteriosclerosis and hyperlipoproteinaemia

Publications (2)

Publication Number Publication Date
AU6212398A true AU6212398A (en) 1998-08-26
AU730109B2 AU730109B2 (en) 2001-02-22

Family

ID=7819326

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62123/98A Ceased AU730109B2 (en) 1997-02-05 1998-01-23 2-amino-substituted pyridines which can be used for the treatment of arteriosclerosis and hyperclipoproteinaemia

Country Status (19)

Country Link
EP (1) EP0973744A1 (en)
JP (1) JP2001510478A (en)
KR (1) KR20000070756A (en)
CN (1) CN1252057A (en)
AU (1) AU730109B2 (en)
BG (1) BG103631A (en)
BR (1) BR9807181A (en)
CA (1) CA2279636A1 (en)
CZ (1) CZ279299A3 (en)
DE (1) DE19704243A1 (en)
HU (1) HUP0001022A2 (en)
ID (1) ID24208A (en)
IL (1) IL131127A0 (en)
NO (1) NO993738L (en)
NZ (1) NZ337011A (en)
PL (1) PL334899A1 (en)
SK (1) SK104099A3 (en)
TR (1) TR199901857T2 (en)
WO (1) WO1998034920A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA12625A (en) 2001-06-22 2006-06-12 Pfizer Prod Inc Pharmaceutical compositions of adsorbates of amorphous drug.
ES2333645T3 (en) 2001-06-22 2010-02-25 Bend Research, Inc. PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF MEDICINES AND NEUTRAL POLYMERS.
EP1469832B2 (en) 2002-02-01 2016-10-26 Bend Research, Inc. Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
BRPI0408442A (en) 2003-03-17 2006-04-04 Japan Tobacco Inc method for increasing the oral bioavailability of s- [2 - ([[1- (2-ethylbutyl) cyclohexyl] carbonyl] amino) phenyl] 2-methylpropanothioate
CA2532931A1 (en) 2003-08-04 2005-02-10 Pfizer Products Inc. Pharmaceutical compositions of adsorbates of amorphous drugs and lipophilic microphase-forming materials
CL2004001884A1 (en) 2003-08-04 2005-06-03 Pfizer Prod Inc DRYING PROCEDURE FOR SPRAYING FOR THE FORMATION OF SOLID DISPERSIONS AMORPHES OF A PHARMACO AND POLYMERS.
EP1670446A2 (en) 2003-09-26 2006-06-21 Japan Tobacco Inc. Method of inhibiting remnant lipoprotein production
DOP2005000123A (en) * 2004-07-02 2011-07-15 Merck Sharp & Dohme CETP INHIBITORS
WO2006032987A1 (en) * 2004-09-23 2006-03-30 Pfizer Products Inc. Indoline compounds and their use in the treatment of arteriosclerosis
WO2006082518A1 (en) 2005-02-03 2006-08-10 Pfizer Products Inc. Pharmaceutical compositions with enhanced performance
US20100113473A1 (en) 2008-10-30 2010-05-06 Player Mark R Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169857A (en) * 1988-01-20 1992-12-08 Bayer Aktiengesellschaft 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis

Also Published As

Publication number Publication date
BR9807181A (en) 2000-01-25
NZ337011A (en) 2001-04-27
CA2279636A1 (en) 1998-08-13
NO993738D0 (en) 1999-08-02
CZ279299A3 (en) 1999-11-17
IL131127A0 (en) 2001-01-28
BG103631A (en) 2000-11-30
TR199901857T2 (en) 1999-10-21
AU730109B2 (en) 2001-02-22
HUP0001022A2 (en) 2000-09-28
DE19704243A1 (en) 1998-08-06
KR20000070756A (en) 2000-11-25
NO993738L (en) 1999-09-17
ID24208A (en) 2000-07-13
WO1998034920A1 (en) 1998-08-13
PL334899A1 (en) 2000-03-27
JP2001510478A (en) 2001-07-31
SK104099A3 (en) 2000-01-18
EP0973744A1 (en) 2000-01-26
CN1252057A (en) 2000-05-03

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired