BE905375A - Use of nifedipine for treating baldness - by topical admin. to promote growth of hair - Google Patents
Use of nifedipine for treating baldness - by topical admin. to promote growth of hair Download PDFInfo
- Publication number
- BE905375A BE905375A BE1/011544A BE1011544A BE905375A BE 905375 A BE905375 A BE 905375A BE 1/011544 A BE1/011544 A BE 1/011544A BE 1011544 A BE1011544 A BE 1011544A BE 905375 A BE905375 A BE 905375A
- Authority
- BE
- Belgium
- Prior art keywords
- nifedipine
- hair
- promote growth
- treating baldness
- baldness
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
Abstract
Use of nifedipine (I) for the topical treatment of baldness is new.
Description
<Desc/Clms Page number 1>
Deze uitvinding stelt een nieuw haargroeimiddel voor.
Tot nu toe, behalve de plantaardige of kruidenmiddelen, bestonden er geen haargroeimiddelen.
Sinds kort bestaat er"Minoxidil", een synthetiseerbare, scheikundige formule, die pretendeert een haargroeimiddel te zijne Dit bloeddrukverlagend produkt gaf"per os"bij bepaalde patiën- ten, als nevenwerking een haargroei over heel het lichaam.
Er wordt nu aan gewerkt om"Minoxidil"voor uitwendig gebruik op de markt te brengen als haargroeimiddel.
Deze uitvinding maakt gebruik vsn een gekend geneesmiddel dat toegepast wordt voor de behandeling"per os"van angina pectoris.
Nifedipine bestaat in kapsules die voor deze toepassing worden doorgesneden.
De olieachtige substantie wordt opgetrokken en in een recipiënt bewaard.'s Avonds wordt een gedeelte van het produkt op de kale schedel ingewreven. Het overtollige wordt verwijderd met een papieren zakdoekje.'s Morgens wordt de schedel met water gereinigd. Deze werkwijze wordt dagelijks herhaald.
Doordat Nifedipine vasodilaterend werkt, brengt het meer zuurstof ter plaatse waardoor het proces dat kaalheid bevordert, tegengegaan wordt.
Dat het produkt lokaal vasodilaterend werkt, kan men tevens zien aan't feit dat de schedelhuid, na inwrijven, een rode kleur heeft en een warmtesensatie geeft.
Nifedipine door de zuurstofbevloeing lokaal te verhogen, werkt ook bactericied, vooral tegen de propionibacterium acnes, dat een anaëroob microob is. Deze verschijnselen zijn in de geneeskunde wel bekend en goed beschreven.
<Desc/Clms Page number 2>
Het effect van Nifedipine, zoals hoger beschreven toegepast, resulteert na enkele maanden in't volgende : eerst krijgt men donshaar op de kale schedel en daarna gaat gaat het donshaar over in een mormale groeifase tot vol- waardig haar.
De snelheid van het groeiproces kan individueel verschillen.
Bijkomende voordelen van Nifedipine voor lokaal gebruik is dat de huid van de schedel en het aangezicht minder vettig wordt.
Tevens vertoont het aangezicht minder meeëters en acné. Tot nu toe vertoont Nifedipine onder lokaal gebruik geen nevenwerkingen en geen bekende allergische reakties.
Nifedipine, lokaal gebruik en vermengd in een olieachtig middel, k-iv) spijtig genoeg niet meermaals daags op de schedelhuid inge- wreven worden wegens het toxisch aspect van de olieachtige oplossing.
Nifedipine, vermengd in andere vormen (crèmes, lotions, shampoos) zullen de eigenschappen van het produkt nog verbeteren.
Crèmes, lotions of shampoos hebben de bekende intrinsieke voordelen op oliën voor de behandeling van de schedelhuid en het haar.
<Desc / Clms Page number 1>
This invention proposes a new hair growth agent.
Until now, apart from the herbal or herbal remedies, there were no hair growth remedies.
Recently, there has been "Minoxidil", a synthesizable chemical formula that purports to be a hair growth product. This antihypertensive product gave "per os" in certain patients, as a side effect, hair growth all over the body.
Work is now underway to market "Minoxidil" for external use as a hair growth product.
The present invention uses a known drug used for the treatment "per os" of angina pectoris.
Nifedipine exists in capsules that are cut for this application.
The oily substance is pulled up and stored in a container. In the evening, part of the product is rubbed onto the bald skull. The excess is removed with a tissue paper.In the morning, the skull is cleaned with water. This procedure is repeated daily.
Because vasodilaterally acting, Nifedipine brings more oxygen to the site, thereby counteracting the baldness promoting process.
It can also be seen that the scalp skin, after rubbing, has a red color and gives a heat sensation.
Nifedipine by locally increasing oxygen flow also acts bactericidal, especially against the propionibacterium acnes, which is an anaerobic microob. These phenomena are well known and well described in medicine.
<Desc / Clms Page number 2>
The effect of Nifedipine, as described above, results after a few months in the following: first one gets down hair on the bald skull and then the down hair goes into a normal growth phase to full hair.
The speed of the growth process can differ individually.
Additional benefits of Nifedipine for topical use are that it makes the skin on the skull and face less oily.
The face also shows fewer blackheads and acne. Until now Nifedipine shows no side effects and no known allergic reactions under local use.
Nifedipine, topical use and mixed in an oily agent, k-iv) unfortunately not rubbed into the scalp several times a day due to the toxic aspect of the oily solution.
Nifedipine, mixed in other forms (creams, lotions, shampoos) will further improve the properties of the product.
Creams, lotions or shampoos have the known intrinsic benefits on oils for the treatment of the scalp and hair.
Claims (5)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE1/011544A BE905375A (en) | 1986-09-04 | 1986-09-04 | Use of nifedipine for treating baldness - by topical admin. to promote growth of hair |
EP87870117A EP0276643A3 (en) | 1986-09-04 | 1987-08-21 | Composition of a hair growth restorer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE905375 | 1986-09-04 | ||
BE1/011544A BE905375A (en) | 1986-09-04 | 1986-09-04 | Use of nifedipine for treating baldness - by topical admin. to promote growth of hair |
Publications (1)
Publication Number | Publication Date |
---|---|
BE905375A true BE905375A (en) | 1986-12-31 |
Family
ID=25661186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1/011544A BE905375A (en) | 1986-09-04 | 1986-09-04 | Use of nifedipine for treating baldness - by topical admin. to promote growth of hair |
Country Status (1)
Country | Link |
---|---|
BE (1) | BE905375A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0319983A1 (en) * | 1987-12-09 | 1989-06-14 | L'oreal | Association of pyrimidine derivatives and calcium antagonists to induce and stimulate the hair growth and to reduce hair loss |
-
1986
- 1986-09-04 BE BE1/011544A patent/BE905375A/en not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0319983A1 (en) * | 1987-12-09 | 1989-06-14 | L'oreal | Association of pyrimidine derivatives and calcium antagonists to induce and stimulate the hair growth and to reduce hair loss |
US5059606A (en) * | 1987-12-09 | 1991-10-22 | L'oreal | Combination of pyrimidine derivatives and calcium antagonists to induce and stimulate hair growth and reduce hair loss |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: COPPE JAN Effective date: 19910930 |