BE902250A - NOVEL ANTIBACTERIAL AND ANTIPROTOZOAL PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION. - Google Patents
NOVEL ANTIBACTERIAL AND ANTIPROTOZOAL PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION.Info
- Publication number
- BE902250A BE902250A BE1/011243A BE1011243A BE902250A BE 902250 A BE902250 A BE 902250A BE 1/011243 A BE1/011243 A BE 1/011243A BE 1011243 A BE1011243 A BE 1011243A BE 902250 A BE902250 A BE 902250A
- Authority
- BE
- Belgium
- Prior art keywords
- antiprotozoal
- pharmaceutical compositions
- preparation
- antibacterial
- acid
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 3
- 230000000842 anti-protozoal effect Effects 0.000 title abstract 3
- 239000003904 antiprotozoal agent Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- KYGZCKSPAKDVKC-UHFFFAOYSA-N Oxolinic acid Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC2=C1OCO2 KYGZCKSPAKDVKC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960000210 nalidixic acid Drugs 0.000 abstract 1
- MHWLWQUZZRMNGJ-UHFFFAOYSA-N nalidixic acid Chemical compound C1=C(C)N=C2N(CC)C=C(C(O)=O)C(=O)C2=C1 MHWLWQUZZRMNGJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 229960000321 oxolinic acid Drugs 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- UURAUHCOJAIIRQ-QGLSALSOSA-N tiamulin Chemical compound CCN(CC)CCSCC(=O)O[C@@H]1C[C@@](C)(C=C)[C@@H](O)[C@H](C)[C@@]23CC[C@@H](C)[C@]1(C)[C@@H]2C(=O)CC3 UURAUHCOJAIIRQ-QGLSALSOSA-N 0.000 abstract 1
- 229960004885 tiamulin Drugs 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
nouvelles compositions pharmaceutiques antibactériennes et antiprotozoaires. Ces compositions synergiques comprennent du fumarate acide de tiamuline et des acides organiques antibactériens et antiprotozoaires tels que l'acide oxolinique ou l'acide nalidixique ou un dérivé soluble dans l'eau, acceptable du point de vue pharmaceutique, de ceux-ci, en un rapport pondéral de 1:5 à 5:1, mélangés à des supports solides ou liquides inertes. Utilisation dans le traitement de maladies infectieuses des voies respiratoires, gastro-intestinales et urogénitales chez les animaux domestiquesnew antibacterial and antiprotozoal pharmaceutical compositions. These synergistic compositions include tiamulin acid fumarate and antibacterial and antiprotozoal organic acids such as oxolinic acid or nalidixic acid or a pharmaceutically acceptable water-soluble derivative thereof, in one. weight ratio of 1: 5 to 5: 1, mixed with inert solid or liquid carriers. Use in the treatment of infectious diseases of the respiratory, gastrointestinal and urogenital tracts in domestic animals
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU841681A HU192982B (en) | 1984-04-28 | 1984-04-28 | Process for producing synergetic pharmaceutical compositions containing thiamulin and antibacterial and antiprotozoal organic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
BE902250A true BE902250A (en) | 1985-10-22 |
Family
ID=10955659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1/011243A BE902250A (en) | 1984-04-28 | 1985-04-22 | NOVEL ANTIBACTERIAL AND ANTIPROTOZOAL PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION. |
Country Status (11)
Country | Link |
---|---|
AT (1) | AT388669B (en) |
BE (1) | BE902250A (en) |
CH (1) | CH666407A5 (en) |
DE (1) | DE3515185A1 (en) |
ES (1) | ES8607333A1 (en) |
GB (1) | GB2158353A (en) |
HU (1) | HU192982B (en) |
IT (1) | IT1200461B (en) |
LU (1) | LU85870A1 (en) |
NL (1) | NL8501061A (en) |
SE (1) | SE8502038L (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4041563A1 (en) * | 1990-12-22 | 1992-06-25 | Sanol Arznei Schwarz Gmbh | METHOD FOR PRODUCING ACTIVE MICROPARTICLES FROM HYDROLYTICALLY DEGRADABLE POLYMERS |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1208279A (en) * | 1967-05-12 | 1970-10-14 | Ici Ltd | Veterinary compositions containing 4-hydroxy-1,8-naphthyridine derivatives |
GB2027590A (en) * | 1978-08-14 | 1980-02-27 | Squibb & Sons Inc | Parenteral compositions containing tiamulin |
CH642850A5 (en) * | 1978-10-20 | 1984-05-15 | Ausonia Farma Srl | PHARMACEUTICAL COMPOSITIONS WITH ANTIBACTERIAL ACTIVITY AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE GERM INFECTIONS. |
GB2072012B (en) * | 1980-03-14 | 1984-07-25 | Squibb & Sons Inc | Veterinary compositions containing pleuromutilin derivatives |
-
1984
- 1984-04-28 HU HU841681A patent/HU192982B/en not_active IP Right Cessation
-
1985
- 1985-04-11 NL NL8501061A patent/NL8501061A/en not_active Application Discontinuation
- 1985-04-22 BE BE1/011243A patent/BE902250A/en not_active IP Right Cessation
- 1985-04-24 CH CH1749/85A patent/CH666407A5/en not_active IP Right Cessation
- 1985-04-24 AT AT0122985A patent/AT388669B/en not_active IP Right Cessation
- 1985-04-26 LU LU85870A patent/LU85870A1/en unknown
- 1985-04-26 ES ES542610A patent/ES8607333A1/en not_active Expired
- 1985-04-26 SE SE8502038A patent/SE8502038L/en not_active Application Discontinuation
- 1985-04-26 DE DE19853515185 patent/DE3515185A1/en not_active Withdrawn
- 1985-04-26 IT IT20515/85A patent/IT1200461B/en active
- 1985-04-26 GB GB08510673A patent/GB2158353A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
GB2158353A (en) | 1985-11-13 |
ATA122985A (en) | 1989-01-15 |
HUT37347A (en) | 1985-12-28 |
DE3515185A1 (en) | 1985-11-07 |
IT1200461B (en) | 1989-01-18 |
SE8502038D0 (en) | 1985-04-26 |
SE8502038L (en) | 1985-10-29 |
GB8510673D0 (en) | 1985-06-05 |
NL8501061A (en) | 1985-11-18 |
LU85870A1 (en) | 1986-11-05 |
ES8607333A1 (en) | 1986-05-16 |
ES542610A0 (en) | 1986-05-16 |
HU192982B (en) | 1987-08-28 |
IT8520515A0 (en) | 1985-04-26 |
AT388669B (en) | 1989-08-10 |
CH666407A5 (en) | 1988-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: HAJDUSAGI AGRARIPARI EGYESULES Effective date: 19920430 |