BE900469A - POLYIONIC MICROENCAPSULATION PROCESS OF A SENSITIVE CENTRAL MATERIAL WITHIN A SEMI-PERMEABLE MEMBRANE, AND CAPSULES OBTAINED. - Google Patents

POLYIONIC MICROENCAPSULATION PROCESS OF A SENSITIVE CENTRAL MATERIAL WITHIN A SEMI-PERMEABLE MEMBRANE, AND CAPSULES OBTAINED.

Info

Publication number
BE900469A
BE900469A BE0/213566A BE213566A BE900469A BE 900469 A BE900469 A BE 900469A BE 0/213566 A BE0/213566 A BE 0/213566A BE 213566 A BE213566 A BE 213566A BE 900469 A BE900469 A BE 900469A
Authority
BE
Belgium
Prior art keywords
semi
permeable membrane
polyionic
central material
microencapsulation process
Prior art date
Application number
BE0/213566A
Other languages
French (fr)
Inventor
A P Jarvis Jr
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of BE900469A publication Critical patent/BE900469A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres

Abstract

On met la matière centrale en suspension dans une solution aqueuse d'une matière polymère contenant des groupes cationiques (glucopolysaccharide aminé).On forme une matrice temporaire en gélifiant des gouttelettes de la suspension à l'aide d'un anion divalent ou multivalent. On réticule de façon permanente la matrice temporaire à l'aide d'une matière polymère contenant plusieurs groupes anioniques (acide polyaspartique ou polyglutamique), pour former une membrane semi-perméable.The central material is suspended in an aqueous solution of a polymeric material containing cationic groups (amino glucopolysaccharide). A temporary matrix is formed by gelling droplets of the suspension using a divalent or multivalent anion. The temporary matrix is permanently crosslinked using a polymeric material containing several anionic groups (polyaspartic or polyglutamic acid), to form a semi-permeable membrane.

BE0/213566A 1983-09-01 1984-08-30 POLYIONIC MICROENCAPSULATION PROCESS OF A SENSITIVE CENTRAL MATERIAL WITHIN A SEMI-PERMEABLE MEMBRANE, AND CAPSULES OBTAINED. BE900469A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52839583A 1983-09-01 1983-09-01

Publications (1)

Publication Number Publication Date
BE900469A true BE900469A (en) 1984-12-17

Family

ID=24105521

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/213566A BE900469A (en) 1983-09-01 1984-08-30 POLYIONIC MICROENCAPSULATION PROCESS OF A SENSITIVE CENTRAL MATERIAL WITHIN A SEMI-PERMEABLE MEMBRANE, AND CAPSULES OBTAINED.

Country Status (14)

Country Link
JP (1) JPS6075326A (en)
AU (1) AU563653B2 (en)
BE (1) BE900469A (en)
CA (1) CA1245984A (en)
CH (1) CH664472A5 (en)
DE (1) DE3432143A1 (en)
DK (1) DK419184A (en)
FR (1) FR2551455B1 (en)
GB (1) GB2145992B (en)
IL (1) IL72787A (en)
IT (1) IT1196742B (en)
NL (1) NL8402671A (en)
NO (1) NO843481L (en)
SE (1) SE8404343L (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60175539A (en) * 1984-02-23 1985-09-09 Snow Brand Milk Prod Co Ltd Capsule and its production
NO166836C (en) * 1985-03-14 1991-09-11 Univ California PROCEDURE FOR TREATMENT OF AN ORGAN TRANSPLANT.
GB8705464D0 (en) * 1987-03-09 1987-04-15 Atomic Energy Authority Uk Composite material
JPS6434436A (en) * 1987-07-28 1989-02-03 Sanyo Chemical Ind Ltd Gel cellular beads and manufacture thereof
CA1319632C (en) * 1988-04-22 1993-06-29 Carol Louise Nolan Method for microbial immobilization
US4952618A (en) * 1988-05-03 1990-08-28 Minnesota Mining And Manufacturing Company Hydrocolloid/adhesive composition
DE3941873A1 (en) * 1989-12-19 1991-06-20 Jakob Dr Bodziony Hollow fibres coated which cells with inhibit coagulation - for long-term use as implants in arteries and veins to carry sensors
DE4012079C2 (en) * 1990-04-14 1997-11-06 Jakob Dr Bodziony Implantable exchange and diffusion chamber
US5487390A (en) * 1990-10-05 1996-01-30 Massachusetts Institute Of Technology Gas-filled polymeric microbubbles for ultrasound imaging
US5149543A (en) * 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
US5562099A (en) * 1990-10-05 1996-10-08 Massachusetts Institute Of Technology Polymeric microparticles containing agents for imaging
FR2694894B1 (en) * 1992-08-20 1994-11-10 Coletica Use of a transacylation reaction between an esterified polysaccharide and a polyamine or polyhydroxylated substance for the manufacture of microparticles, process and composition.
FR2703927B1 (en) * 1993-04-13 1995-07-13 Coletica Use of a transacylation reaction between an esterified polysaccharide and a polyamine to form in an aqueous medium a membrane at least on the surface of gelled particles.
DE4312970A1 (en) * 1993-04-21 1994-10-27 Juergen Dr Schrezenmeir Microcapsule and process and apparatus for production thereof
DE4426396A1 (en) * 1994-07-26 1996-02-01 Ulrich Prof Dr Zimmermann Process for the preparation of concentrated solutions of microencapsulated cells or of suspended active substances in microencapsulated form
US5540927A (en) * 1995-04-12 1996-07-30 Monsanto Company Microencapsulation process by coacervation
ATE316420T1 (en) * 1998-03-19 2006-02-15 Max Planck Gesellschaft PRODUCTION OF NANO AND MICRO CAPSULES BY LAYER-WIDE POLYELECTROLYTE SELF-ASSEMBLY
US7101575B2 (en) 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
DE102004013637A1 (en) 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Process for the preparation of CS particles and microcapsules using porous templates as well as CS particles and microcapsules
DE102005002483A1 (en) * 2005-01-18 2006-08-03 Ehrfeld Mikrotechnik Bts Gmbh Method for encapsulating sensor molecules with a semipermeable membrane
FR2986165B1 (en) 2012-01-31 2015-07-24 Capsum PROCESS FOR PREPARING RIGIDIFIED CAPSULES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
NO158284C (en) * 1981-03-13 1988-08-17 Damon Biotech Inc PROCEDURE FOR SELECTIVE USE OF A PERMEABLE MEMBRANE.

Also Published As

Publication number Publication date
IT1196742B (en) 1988-11-25
GB2145992A (en) 1985-04-11
GB2145992B (en) 1987-02-18
NL8402671A (en) 1985-04-01
FR2551455A1 (en) 1985-03-08
IT8467874A0 (en) 1984-09-03
CA1245984A (en) 1988-12-06
SE8404343L (en) 1985-03-02
GB8422052D0 (en) 1984-10-03
AU3263484A (en) 1985-03-07
DK419184A (en) 1985-03-02
IL72787A0 (en) 1984-11-30
JPS6075326A (en) 1985-04-27
CH664472A5 (en) 1988-03-15
NO843481L (en) 1985-03-04
DK419184D0 (en) 1984-08-31
SE8404343D0 (en) 1984-08-31
FR2551455B1 (en) 1989-09-15
DE3432143C2 (en) 1987-05-14
IL72787A (en) 1987-12-31
AU563653B2 (en) 1987-07-16
DE3432143A1 (en) 1985-03-21
IT8467874A1 (en) 1986-03-03

Similar Documents

Publication Publication Date Title
BE900469A (en) POLYIONIC MICROENCAPSULATION PROCESS OF A SENSITIVE CENTRAL MATERIAL WITHIN A SEMI-PERMEABLE MEMBRANE, AND CAPSULES OBTAINED.
ATE43796T1 (en) PROCESS FOR PRODUCTION OF MICROCAPSULES BY INTERFACIAL POLYADDITION.
FR2597367B1 (en) PROCESS FOR FACILITATING THE FORMATION OF LIPID SPHERULES DISPERSION IN AN AQUEOUS PHASE AND FOR IMPROVING THEIR STABILITY AND THEIR ENCAPSULATION RATE, AND CORRESPONDING DISPERSIONS.
FR2517315B1 (en) PROCESS FOR THE PREPARATION OF NEW FORMS OF COLLAGEN, NATIVE OR DERETICULATED, WITH PRESERVED HELICOIDAL STRUCTURE, ASSOCIATED WITH MUCOPOLYSACCHARIDES AND THEIR APPLICATIONS IN PARTICULAR IN THE COSMETOLOGICAL, PHARMACEUTICAL, ANALYTICAL AND OTHER FIELDS
FR2465508B1 (en) POROUS MEMBRANES CONTAINING MODIFIED POLYACRYLONITRILE, FOR ULTRAFILTRATION, PROCESS FOR PREPARING THE SAME AND APPLICATIONS THEREOF
KR880000106A (en) Sustained Release Pharmaceutical Formulations
ATE112788T1 (en) SUSPENSION OF WATER-SOLUBLE POLYMERS IN AQUEOUS MEDIA CONTAINING DISSOLVED SALTS.
RO62798A (en) PROCESS FOR THE PREPARATION OF ASYMMETRIC ESTERS OF N-SUBSTITUTED 1,4-DIHYDROPYRIDIN-3,5-DICARBOXYLIC ACID
FR2610313B1 (en) SYNTHETIC STEVENSITY, ION EXCHANGE MATERIAL, AQUEOUS THICKENING AGENT AND HYDROGEL CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME
BE808108A (en) PROCESS FOR THE PREPARATION OF SOLUTIONS OF PERCARBOXYLIC ACID IN ORGANIC SOLVENTS
FR2419742A1 (en) PROCESS FOR IMPROVING THE PERFORMANCES OF SEMIPERMEABLE MEMBRANES
FR2674256B1 (en) PROCESS FOR SEPARATING IRON AND / OR ZIRCONIUM FROM ACTINIDES AND / OR LANTHANIDES PRESENT IN AN AQUEOUS ACID SOLUTION USING A PROPANEDIAMIDE.
BE887894A (en) PROCESS FOR THE PREPARATION OF DIRECT YELLOW DYE IN THE FORM OF STABLE CONCENTRATED SOLUTIONS, SOLUTIONS OBTAINED AND APPLICATIONS
DE59910671D1 (en) microcapsules
FR2370510A1 (en) PROCESS FOR ENCAPSULATING A LABILE BIOLOGICAL MATERIAL
GB1377516A (en) Method of preparing microcapsules
FR2634121B1 (en) PROCESS FOR THE PREPARATION OF COLLAGEN MICROPARTICLES AND PRODUCTS OBTAINED
FR2548232B1 (en) NOVEL PRE-CONDENSATE, STABLE AQUEOUS PRE-CONDENSATE DISPERSION, AND USE THEREOF IN A PROCESS FOR THE AFTER-TREATMENT OF SUBSTRATES CONTAINING HYDROXY, AMINO OR THIOL GROUPS
GB1475807A (en) Polyamide concentrates containing sulphonate groups
AT294046B (en) Process for the preparation of N, N'-bis [2- (3 ', 4'-dihydroxyphenyl) -2-hydroxyethyl] -hexamethylenediamine, its optically active forms and the salts thereof
FR2285175A1 (en) SEPARATION OF CATALYST PARTICLES FROM A SUSPENSION OF THESE PARTICLES IN AN AQUEOUS HYDROXYLAMMONIUM SALT SOLUTION
FR2462924B1 (en) PROCESS FOR REDUCING THE NICKEL CONTENT OF AN AQUEOUS SOLUTION CONTAINING COBALT IONS (II)
SU419533A1 (en)
FR2283177A1 (en) COMPOSITION FOR COATING IN THE FORM OF AQUEOUS SOLUTION OF POLYESTER AND DIAMINE OF ORTHOAMIC ACID
RO62300A (en) PROCESS FOR THE PREPARATION OF FORMIC ACID N- (O, S-DIALKYL- (THIONO) -THIOLPHOSPHORYL) -IMINOALKYLESTERS

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DAMON BIOTECH INC.

Effective date: 19890831