BE892479A - Procede et ensemble de production de substances formees par des cellules vivantes. - Google Patents

Procede et ensemble de production de substances formees par des cellules vivantes.

Info

Publication number
BE892479A
BE892479A BE0/207559A BE207559A BE892479A BE 892479 A BE892479 A BE 892479A BE 0/207559 A BE0/207559 A BE 0/207559A BE 207559 A BE207559 A BE 207559A BE 892479 A BE892479 A BE 892479A
Authority
BE
Belgium
Prior art keywords
assembly
living cells
substances formed
producing substances
producing
Prior art date
Application number
BE0/207559A
Other languages
English (en)
Inventor
F Lim
Original Assignee
Damon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Corp filed Critical Damon Corp
Publication of BE892479A publication Critical patent/BE892479A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/32—Polylysine, polyornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate
BE0/207559A 1981-03-13 1982-03-12 Procede et ensemble de production de substances formees par des cellules vivantes. BE892479A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24358381A 1981-03-13 1981-03-13

Publications (1)

Publication Number Publication Date
BE892479A true BE892479A (fr) 1982-07-01

Family

ID=22919321

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/207559A BE892479A (fr) 1981-03-13 1982-03-12 Procede et ensemble de production de substances formees par des cellules vivantes.

Country Status (11)

Country Link
JP (2) JPS5816693A (fr)
BE (1) BE892479A (fr)
CA (1) CA1172961A (fr)
CH (1) CH654328A5 (fr)
DE (1) DE3209127A1 (fr)
DK (1) DK112282A (fr)
FR (1) FR2503183B1 (fr)
GB (1) GB2094833B (fr)
IT (1) IT1150682B (fr)
NO (1) NO163060C (fr)
SE (1) SE454780B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO161446C (no) * 1981-03-13 1989-08-16 Damon Biotech Inc Fremgangsmaate for dyrking av celler som er avhengige av forankring.
US4582799A (en) * 1983-04-15 1986-04-15 Damon Biotech, Inc. Process for recovering nonsecreted substances produced by cells
CA1196862A (fr) * 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulement de cellules et de tissus vivants
JPS6025929A (ja) * 1983-07-20 1985-02-08 ザ・スト−ル・リサ−チ・アンド・デイベロツプメント・コ−ポレ−シヨン カプセル化細胞、その製造方法および用途
JPS60141281A (ja) * 1983-12-28 1985-07-26 Meiji Milk Prod Co Ltd 菌体顆粒の製造方法及び装置
EP0152898B1 (fr) * 1984-02-15 1990-01-17 Massachusetts Institute Of Technology Procédé d'encapsulation et systèmes à base de matières actives encapsulées
JPS60175539A (ja) * 1984-02-23 1985-09-09 Snow Brand Milk Prod Co Ltd カプセル体およびその製造法
US5672347A (en) * 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
GR851626B (fr) * 1984-07-05 1985-11-26 Genentech Inc
US6686455B1 (en) 1984-07-05 2004-02-03 Genentech, Inc. Tumor necrosis factor
CA1241598A (fr) * 1984-07-11 1988-09-06 Connaught Laboratories Limited Generation de gouttelettes
EP0199362A3 (fr) * 1985-04-26 1987-10-07 Massachusetts Institute Of Technology Système et dispositif pour la libération retardée et par à-coups de substances biologiquement actives
CA1265443A (fr) * 1985-09-18 1990-02-06 Elieser Gorelik Epreuves de sensibilite aux agents chimiotherapeutiques
DE3534983A1 (de) * 1985-10-01 1987-04-02 Sturge John & E Ltd Komplexe immobilisierte biokatalysatoren sowie ihre herstellung und anwendung
JPS62166891A (ja) * 1986-01-20 1987-07-23 Snow Brand Milk Prod Co Ltd 細胞培養による有用物質の製造方法
WO1987004367A1 (fr) * 1986-01-23 1987-07-30 Ltl Associates Membranes covalentes
DE3615043A1 (de) * 1986-05-03 1987-11-05 Hoechst Ag Verfahren zur verkapselung von biologisch aktivem material
IL79052A0 (en) * 1986-06-06 1986-11-30 Univ Ramot Device and process for production of alginate-shell beads containing biologically active material
JP2530690Y2 (ja) * 1986-08-28 1997-03-26 カシオ計算機株式会社 電子楽器
US5010010A (en) * 1986-10-22 1991-04-23 Selmer-Sande, A.S. Production of human parathyroid hormone from microorganisms
EP0604706A1 (fr) 1986-10-22 1994-07-06 GAUTVIK, Kaare M., Dr. Production d'une hormone humaine de parathyroide à partir de microorganismes
US5420242A (en) * 1986-10-22 1995-05-30 Kaare M. Gautvik Production of human parathyroid hormone from microorganisms
JPH02504221A (ja) * 1987-04-22 1990-12-06 ベイ　ミカエル 細胞培養法、培養物及び培養製品
JPS6414225U (fr) * 1987-07-15 1989-01-25
JPH025797U (fr) * 1988-06-23 1990-01-16
WO1991010470A1 (fr) * 1990-01-08 1991-07-25 Brown University Research Foundation Dispositifs et procedes d'apport ameliore de facteurs actifs
AU666118B2 (en) * 1991-04-25 1996-02-01 Brown University Research Foundation Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
DE4229526B4 (de) * 1992-09-07 2006-02-16 Schrezenmeir, Jürgen, Dr. Vorrichtung zur Aufnahme und zum Einbringen von biologisch aktiven Geweben oder Zellen in den menschlichen Körper
DK0802800T3 (da) * 1993-08-12 2002-10-07 Neurotech Sa Biokompatible immunoisolatoriske kapsler indeholdende genetisk ændrede celler for levering af biologisk aktive molekyler
US5908623A (en) 1993-08-12 1999-06-01 Cytotherapeutics, Inc. Compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5550050A (en) * 1994-04-15 1996-08-27 Cytotherapeutics, Inc. Method for implanting encapsulated cells in a host
DE4426396A1 (de) * 1994-07-26 1996-02-01 Ulrich Prof Dr Zimmermann Verfahren zur Herstellung konzentrierter Lösungen von mikroverkapselten Zellen oder von suspendierten Wirkstoffen in mikroverkapselter Form
US5916790A (en) * 1995-03-03 1999-06-29 Metabolex, Inc. Encapsulation compositions, and methods
SE9702401D0 (sv) 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
EP3156480B1 (fr) * 2011-02-07 2020-03-25 Life Technologies Corporation Compositions et procédés de stabilisation de composés sensibles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4324683A (en) * 1975-08-20 1982-04-13 Damon Corporation Encapsulation of labile biological material
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
NO158284C (no) * 1981-03-13 1988-08-17 Damon Biotech Inc Fremgangsmaate for selektiv oppbrytning av en permeabel membran.
NO161446C (no) * 1981-03-13 1989-08-16 Damon Biotech Inc Fremgangsmaate for dyrking av celler som er avhengige av forankring.

Also Published As

Publication number Publication date
IT1150682B (it) 1986-12-17
CH654328A5 (de) 1986-02-14
FR2503183A1 (fr) 1982-10-08
FR2503183B1 (fr) 1985-11-08
CA1172961A (fr) 1984-08-21
GB2094833B (en) 1984-06-20
JPS6244919B2 (fr) 1987-09-24
GB2094833A (en) 1982-09-22
NO820794L (no) 1982-09-14
DE3209127C2 (fr) 1988-02-04
JPS6157288B2 (fr) 1986-12-06
SE454780B (sv) 1988-05-30
IT8220140A0 (it) 1982-03-12
DE3209127A1 (de) 1982-12-09
JPS6188893A (ja) 1986-05-07
NO163060B (no) 1989-12-18
NO163060C (no) 1990-03-28
JPS5816693A (ja) 1983-01-31
DK112282A (da) 1982-09-14
SE8201554L (sv) 1982-09-14

Similar Documents

Publication Publication Date Title
BE892479A (fr) Procede et ensemble de production de substances formees par des cellules vivantes.
BE888297A (fr) Procede de production de microcapsules,
FR2558156B1 (fr) Procede de produ
FR2605185B1 (fr) Procede de culture des plantes
BE874620A (fr) Procede et installation de production de methane
BE875929A (fr) Procede de production de panneaux cellulosiques
FR2593175B1 (fr) Procede de production de 3-phenyl-4-cyanopyrroles.
BE866192A (fr) Procede et installation hydraulique de production d'energie
BE892269A (fr) Cataplasme analgesique et anti-inflammatoire et son procede de production
FR2338287A1 (fr) Polysaccharide ayant la propriete de former un gel et procede microbiologique pour sa preparation
BE866171A (fr) L-sucrose et procede pour sa production
FR2511035B1 (fr) Procede de production de l-lysine par fermentation
FR2504131B1 (fr) Procede de production de dithioacides organiques et leur application
FR2342339A1 (fr) Procede de production de polysaccharides par fermentation
BE895510A (fr) Procede de production de produit caustiques, ensemble unitaire membrane-electrodes et structure d'electrode multicouches.
LU80402A1 (fr) Procede de production de 2,6-diaminonebularines
BE891334A (fr) Procede de production de coke
FR2519030B1 (fr) Procede de production de produit caustique, ensemble unitaire membrane-electrode et structure d'electrodes multicouches
BE865758A (fr) Procede de production de cyclobutanones
IT7922634A0 (it) Enzima immobilizzato e metodo per la sua produzione.
FR2477540B1 (fr) Procede de production de 5-chloro-b-trifluoromethylpyridines
BE885672A (fr) Procede de production d'electrode
FR2575178B1 (fr) Procede de production de polysaccharides de type xanthane
FR2438640B1 (fr) Procede de production de monoalcoyl-aromatiques
FR2510571B1 (fr) Spirothiazolidinedione, son procede de production et preparation pharmaceutique la contenant

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DAMON BIOTECH INC.

Effective date: 19980331