BE892479A - PROCESS AND ASSEMBLY FOR PRODUCING SUBSTANCES FORMED BY LIVING CELLS. - Google Patents

PROCESS AND ASSEMBLY FOR PRODUCING SUBSTANCES FORMED BY LIVING CELLS.

Info

Publication number
BE892479A
BE892479A BE0/207559A BE207559A BE892479A BE 892479 A BE892479 A BE 892479A BE 0/207559 A BE0/207559 A BE 0/207559A BE 207559 A BE207559 A BE 207559A BE 892479 A BE892479 A BE 892479A
Authority
BE
Belgium
Prior art keywords
assembly
living cells
substances formed
producing substances
producing
Prior art date
Application number
BE0/207559A
Other languages
French (fr)
Inventor
F Lim
Original Assignee
Damon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Corp filed Critical Damon Corp
Publication of BE892479A publication Critical patent/BE892479A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/32—Polylysine, polyornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BE0/207559A 1981-03-13 1982-03-12 PROCESS AND ASSEMBLY FOR PRODUCING SUBSTANCES FORMED BY LIVING CELLS. BE892479A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24358381A 1981-03-13 1981-03-13

Publications (1)

Publication Number Publication Date
BE892479A true BE892479A (en) 1982-07-01

Family

ID=22919321

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/207559A BE892479A (en) 1981-03-13 1982-03-12 PROCESS AND ASSEMBLY FOR PRODUCING SUBSTANCES FORMED BY LIVING CELLS.

Country Status (11)

Country Link
JP (2) JPS5816693A (en)
BE (1) BE892479A (en)
CA (1) CA1172961A (en)
CH (1) CH654328A5 (en)
DE (1) DE3209127A1 (en)
DK (1) DK112282A (en)
FR (1) FR2503183B1 (en)
GB (1) GB2094833B (en)
IT (1) IT1150682B (en)
NO (1) NO163060C (en)
SE (1) SE454780B (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO161446C (en) * 1981-03-13 1989-08-16 Damon Biotech Inc PROCEDURE FOR CULTING CELLS RELATED TO ANCHORING.
US4582799A (en) * 1983-04-15 1986-04-15 Damon Biotech, Inc. Process for recovering nonsecreted substances produced by cells
CA1196862A (en) * 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulation of living tissue and cells
JPS6025929A (en) * 1983-07-20 1985-02-08 ザ・スト−ル・リサ−チ・アンド・デイベロツプメント・コ−ポレ−シヨン Encapsulated cell, manufacture and use
JPS60141281A (en) * 1983-12-28 1985-07-26 Meiji Milk Prod Co Ltd Method and apparatus for producing granule of microorganism
DE3575375D1 (en) * 1984-02-15 1990-02-22 Massachusetts Inst Technology ENCLOSURE METHOD AND SYSTEMS WITH ENCLOSED ACTIVE MATERIAL.
JPS60175539A (en) * 1984-02-23 1985-09-09 Snow Brand Milk Prod Co Ltd Capsule and its production
US6686455B1 (en) 1984-07-05 2004-02-03 Genentech, Inc. Tumor necrosis factor
GR851626B (en) * 1984-07-05 1985-11-26 Genentech Inc
US5672347A (en) * 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
CA1241598A (en) * 1984-07-11 1988-09-06 Connaught Laboratories Limited Droplet generation
EP0199362A3 (en) * 1985-04-26 1987-10-07 Massachusetts Institute Of Technology System and apparatus for delayed and pulsed release of biologically active substances
CA1265443A (en) * 1985-09-18 1990-02-06 Elieser Gorelik Assays for chemotherapeutic agents
DE3534983A1 (en) * 1985-10-01 1987-04-02 Sturge John & E Ltd COMPLEX IMMOBILIZED BIOCATALYSTS AND THEIR PRODUCTION AND USE
JPS62166891A (en) * 1986-01-20 1987-07-23 Snow Brand Milk Prod Co Ltd Production of useful substance by cell cultivation
WO1987004367A1 (en) * 1986-01-23 1987-07-30 Ltl Associates Covalent membranes
DE3615043A1 (en) * 1986-05-03 1987-11-05 Hoechst Ag METHOD FOR ENCODING BIOLOGICALLY ACTIVE MATERIAL
IL79052A0 (en) * 1986-06-06 1986-11-30 Univ Ramot Device and process for production of alginate-shell beads containing biologically active material
JP2530690Y2 (en) * 1986-08-28 1997-03-26 カシオ計算機株式会社 Electronic musical instrument
US5010010A (en) * 1986-10-22 1991-04-23 Selmer-Sande, A.S. Production of human parathyroid hormone from microorganisms
US5420242A (en) * 1986-10-22 1995-05-30 Kaare M. Gautvik Production of human parathyroid hormone from microorganisms
JP2777132B2 (en) 1986-10-22 1998-07-16 カーレ・エンム・ガウトビク Microbial production of human parathyroid hormone
AU614747B2 (en) * 1987-04-22 1991-09-12 Michael Bay Cell culture of anchorage dependent cells, materials and products
JPS6414225U (en) * 1987-07-15 1989-01-25
JPH025797U (en) * 1988-06-23 1990-01-16
WO1991010470A1 (en) * 1990-01-08 1991-07-25 Brown University Research Foundation Devices and methods for enhanced delivery of active factors
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
DE69221484T2 (en) * 1991-04-25 1998-02-19 Univ Brown Res Found IMPLANTABLE, BIOCOMPATIBLE IMMUNISOLATOR SUPPORT SUBSTANCE FOR DELIVERING SELECTED, THERAPEUTIC PRODUCTS
DE4229526B4 (en) * 1992-09-07 2006-02-16 Schrezenmeir, Jürgen, Dr. Device for receiving and introducing biologically active tissues or cells into the human body
US5908623A (en) 1993-08-12 1999-06-01 Cytotherapeutics, Inc. Compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
AU7568094A (en) * 1993-08-12 1995-03-14 Cytotherapeutics, Inc. Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5550050A (en) * 1994-04-15 1996-08-27 Cytotherapeutics, Inc. Method for implanting encapsulated cells in a host
DE4426396A1 (en) * 1994-07-26 1996-02-01 Ulrich Prof Dr Zimmermann Process for the preparation of concentrated solutions of microencapsulated cells or of suspended active substances in microencapsulated form
US5916790A (en) * 1995-03-03 1999-06-29 Metabolex, Inc. Encapsulation compositions, and methods
SE9702401D0 (en) 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
EP2778221B1 (en) * 2011-02-07 2017-07-26 Life Technologies Corporation Compositions and methods for stabilizing susceptible compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4324683A (en) * 1975-08-20 1982-04-13 Damon Corporation Encapsulation of labile biological material
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
NO158284C (en) * 1981-03-13 1988-08-17 Damon Biotech Inc PROCEDURE FOR SELECTIVE USE OF A PERMEABLE MEMBRANE.
NO161446C (en) * 1981-03-13 1989-08-16 Damon Biotech Inc PROCEDURE FOR CULTING CELLS RELATED TO ANCHORING.

Also Published As

Publication number Publication date
SE454780B (en) 1988-05-30
SE8201554L (en) 1982-09-14
FR2503183A1 (en) 1982-10-08
JPS6244919B2 (en) 1987-09-24
DE3209127A1 (en) 1982-12-09
NO820794L (en) 1982-09-14
JPS6188893A (en) 1986-05-07
IT8220140A0 (en) 1982-03-12
NO163060C (en) 1990-03-28
DE3209127C2 (en) 1988-02-04
JPS6157288B2 (en) 1986-12-06
NO163060B (en) 1989-12-18
JPS5816693A (en) 1983-01-31
CH654328A5 (en) 1986-02-14
CA1172961A (en) 1984-08-21
DK112282A (en) 1982-09-14
GB2094833B (en) 1984-06-20
GB2094833A (en) 1982-09-22
FR2503183B1 (en) 1985-11-08
IT1150682B (en) 1986-12-17

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DAMON BIOTECH INC.

Effective date: 19980331