BE881752A - NOVEL HYDROXYLATED PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE - Google Patents

NOVEL HYDROXYLATED PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE

Info

Publication number
BE881752A
BE881752A BE0/199421A BE199421A BE881752A BE 881752 A BE881752 A BE 881752A BE 0/199421 A BE0/199421 A BE 0/199421A BE 199421 A BE199421 A BE 199421A BE 881752 A BE881752 A BE 881752A
Authority
BE
Belgium
Prior art keywords
preparation
therapeutic use
pyrimidine derivatives
novel hydroxylated
hydroxylated
Prior art date
Application number
BE0/199421A
Other languages
French (fr)
Inventor
A Esanu
Original Assignee
Soc D Etudes Prod Chimique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26270867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE881752(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Soc D Etudes Prod Chimique filed Critical Soc D Etudes Prod Chimique
Publication of BE881752A publication Critical patent/BE881752A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE0/199421A 1979-03-10 1980-02-15 NOVEL HYDROXYLATED PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE BE881752A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7908494 1979-03-10
GB7914987 1979-04-30

Publications (1)

Publication Number Publication Date
BE881752A true BE881752A (en) 1980-05-30

Family

ID=26270867

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/199421A BE881752A (en) 1979-03-10 1980-02-15 NOVEL HYDROXYLATED PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE

Country Status (24)

Country Link
JP (1) JPS55122768A (en)
AR (1) AR222691A1 (en)
AU (1) AU533547B2 (en)
BE (1) BE881752A (en)
CA (1) CA1132561A (en)
CH (1) CH644368A5 (en)
DE (3) DE3050999C2 (en)
EG (1) EG14282A (en)
FI (1) FI66357C (en)
FR (2) FR2451370A1 (en)
GB (1) GB2045756B (en)
HK (1) HK55383A (en)
IE (1) IE49547B1 (en)
IN (1) IN153791B (en)
LU (1) LU82185A1 (en)
MX (1) MX6218E (en)
MY (1) MY8400200A (en)
NL (1) NL184833C (en)
NO (1) NO154054C (en)
NZ (1) NZ192927A (en)
OA (1) OA06484A (en)
PT (1) PT70882A (en)
SE (1) SE435180B (en)
SG (1) SG22683G (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348957A (en) * 1991-09-09 1994-09-20 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE894517A (en) * 1981-10-16 1983-01-17 Sod Conseils Rech Applic NEW ISOPROPYLAMINO PYRIMIDINE DERIVATIVE, ITS PREPARATION AND THERAPEUTIC COMPOSITION BASED ON ITS COMPOUNDS
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
US4673677A (en) * 1983-10-03 1987-06-16 Pfizer Inc. Method for treatment of gastrointestinal disorders
US4711888A (en) 1985-07-24 1987-12-08 Pfizer Inc. Hydroxy and alkoxy pyrimidines
WO1989000423A1 (en) * 1987-07-09 1989-01-26 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US4910204A (en) * 1988-06-28 1990-03-20 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
US4940712A (en) * 1989-05-26 1990-07-10 Pfizer Inc. Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US9133212B1 (en) * 2005-06-15 2015-09-15 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB741667A (en) * 1952-12-05 1955-12-07 Ici Ltd New pyrimidine derivatives
GB756189A (en) * 1954-02-01 1956-08-29 Ici Ltd New pyrimidine derivatives
ZA711152B (en) * 1970-03-02 1971-11-24 Ici Ltd Manufacture of pyrimidines
GB1525995A (en) * 1976-02-18 1978-09-27 Soc D Etudes Prod Chimique Aminopyrimidine salt

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348957A (en) * 1991-09-09 1994-09-20 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents

Also Published As

Publication number Publication date
NZ192927A (en) 1981-07-13
FR2451370B1 (en) 1983-05-13
NL8001289A (en) 1980-09-12
FI66357C (en) 1984-10-10
AU533547B2 (en) 1983-12-01
MX6218E (en) 1984-12-21
NO800664L (en) 1980-09-11
DE3016752C2 (en) 1987-06-25
EG14282A (en) 1983-09-30
NO154054B (en) 1986-04-01
IE49547B1 (en) 1985-10-30
CH644368A5 (en) 1984-07-31
AU5624880A (en) 1980-09-18
DE3009071C2 (en) 1985-11-14
NL184833B (en) 1989-06-16
CA1132561A (en) 1982-09-28
GB2045756A (en) 1980-11-05
NL184468B (en) 1989-03-01
NL184833C (en) 1989-11-16
HK55383A (en) 1983-11-25
NO154054C (en) 1986-07-09
LU82185A1 (en) 1980-06-06
AR222691A1 (en) 1981-06-15
OA06484A (en) 1981-07-31
JPS55122768A (en) 1980-09-20
GB2045756B (en) 1983-01-26
DE3016752A1 (en) 1980-12-04
IN153791B (en) 1984-08-18
FR2451191A1 (en) 1980-10-10
FI66357B (en) 1984-06-29
DE3050999A1 (en) 1985-08-14
SE8001812L (en) 1980-09-11
MY8400200A (en) 1984-12-31
FR2451191B1 (en) 1983-04-29
IE800477L (en) 1980-09-10
SE435180B (en) 1984-09-10
FR2451370A1 (en) 1980-10-10
JPS6126996B2 (en) 1986-06-23
FI800566A (en) 1980-09-11
SG22683G (en) 1983-12-16
PT70882A (en) 1980-03-01
DE3050999C2 (en) 1986-08-14
DE3009071A1 (en) 1980-09-11

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SOC. D ETUDES DE PRODUITS CHIMIQUES

Effective date: 19900228