BE876897A - NEW DERIVATIVES OF N-PHENETHYL IMIDAZOLE AND THEIR PREPARATION - Google Patents

NEW DERIVATIVES OF N-PHENETHYL IMIDAZOLE AND THEIR PREPARATION

Info

Publication number
BE876897A
BE876897A BE0/195675A BE195675A BE876897A BE 876897 A BE876897 A BE 876897A BE 0/195675 A BE0/195675 A BE 0/195675A BE 195675 A BE195675 A BE 195675A BE 876897 A BE876897 A BE 876897A
Authority
BE
Belgium
Prior art keywords
emi
preparation
new derivatives
human
compounds
Prior art date
Application number
BE0/195675A
Other languages
French (fr)
Inventor
S Maggiori
A Pillan
F Trane
I Carneri
P Cozzi
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE876897A publication Critical patent/BE876897A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

       

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et leur préparation   <EMI ID=2.1> 

  

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 <EMI ID=4.1>  

  
 <EMI ID=5.1>   <EMI ID=6.1>   <EMI ID=7.1>  

  
 <EMI ID=8.1> 

  
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 <EMI ID=10.1>  

  
 <EMI ID=11.1>   <EMI ID=12.1>   <EMI ID=13.1> 

  
sels avec l'acide nitrique^ Les formules structurales  des composés énumérés ci-dessus indiquées conformément  leur numéro d'ordre progressif" figurent dans le  tableau qui le suit: 

  

 <EMI ID=14.1> 
 

  

 <EMI ID=15.1> 
 

  

 <EMI ID=16.1> 
 

  

 <EMI ID=17.1> 
 

  

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peut préparer les composés conformes à 

  
 <EMI ID=19.1> 

  

 <EMI ID=20.1> 


  
 <EMI ID=21.1> 

  

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 <EMI ID=23.1>   <EMI ID=24.1>  <EMI ID=25.1> 

  
 <EMI ID=26.1>  <EMI ID=27.1>  <EMI ID=28.1> 

  
 <EMI ID=29.1> 

  
 <EMI ID=30.1>   <EMI ID=31.1> 

  

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 <EMI ID=33.1>  

  
 <EMI ID=34.1> 

  
'&#65533;'&#65533;e,&#65533;&#65533;'&#65533;.&#65533;,. 

  
 <EMI ID=35.1>  l'alcool méthylique ou éthylique, par exemple" ou par

  
 <EMI ID=36.1> 

  
 <EMI ID=37.1> 

  
 <EMI ID=38.1> 

  
 <EMI ID=39.1> 

  
 <EMI ID=40.1> 

  
reflux, pendant des périodes de réaction qui 'varient

  
 <EMI ID=41.1>  <EMI ID=42.1>  lyseur approprié tel que, par exemple, le palladium,

  
 <EMI ID=43.1> 

  
 <EMI ID=44.1> 

  
le groupe formé par l'alcool éthylique, 1 'alcool

  
 <EMI ID=45.1> 

  
 <EMI ID=46.1> 

  
 <EMI ID=47.1> 

  
 <EMI ID=48.1>  <EMI ID=49.1> 

  
 <EMI ID=50.1> 

  
 <EMI ID=51.1> 

  
un cation, par exemple un cation alcalin, partir des 

  
 <EMI ID=52.1> 

  
 <EMI ID=53.1> 

  
 <EMI ID=54.1> 

  
 <EMI ID=55.1> 

  
l'hydrure d'un métal alcalin, de l'hydrure  <EMI ID=56.1> 

  
 <EMI ID=57.1> 

  
 <EMI ID=58.1> 

  
 <EMI ID=59.1> 

  
 <EMI ID=60.1> 

  
 <EMI ID=61.1> 

  
 <EMI ID=62.1> 

  
 <EMI ID=63.1> 

  
 <EMI ID=64.1>  <EMI ID=65.1> 
- oeuvre de procédé par exemple. par traitement à <EMI ID=66.1> 

  
 <EMI ID=67.1>  

  
 <EMI ID=68.1> 

  

 <EMI ID=69.1> 


  
 <EMI ID=70.1>  <EMI ID=71.1>  <EMI ID=72.1>   <EMI ID=73.1>  

  
 <EMI ID=74.1> 

  
de concentrations inhibitrices minimales, varient de 

  
 <EMI ID=75.1> 

  
 <EMI ID=76.1> 

  
 <EMI ID=77.1>  

  
On a obtenu de manière analogue des données

  
 <EMI ID=78.1>  <EMI ID=79.1> 

  
Les compositions pharmaceutiques contenant

  
 <EMI ID=80.1> 

  
 <EMI ID=81.1>  <EMI ID=82.1>  <EMI ID=83.1>  <EMI ID=84.1> 

  
 <EMI ID=85.1>  <EMI ID=86.1> 

  
 <EMI ID=87.1> 

  
 <EMI ID=88.1> 

  
 <EMI ID=89.1>   <EMI ID=90.1> 

  
préparer les 'bougies vaginales de manière classique. 

  
 <EMI ID=91.1> 

  
 <EMI ID=92.1> 

  
 <EMI ID=93.1> 

  
 <EMI ID=94.1> 

  
 <EMI ID=95.1> 

  
 <EMI ID=96.1> 

  
 <EMI ID=97.1> 

  
 <EMI ID=98.1> 

  
sil de lotion. 

  
 <EMI ID=99.1> 

  
 <EMI ID=100.1>   <EMI ID=101.1> 

  
 <EMI ID=102.1> 

  
 <EMI ID=103.1>   <EMI ID=104.1>  <EMI ID=105.1>  <EMI ID=106.1> 

  
 <EMI ID=107.1> 

  

 <EMI ID=108.1> 


  
 <EMI ID=109.1>  . mise en oeuvre du môme procédé: 

  
 <EMI ID=110.1> 

  
 <EMI ID=111.1> 

  
 <EMI ID=112.1> 

  
 <EMI ID=113.1> 

  
 <EMI ID=114.1> 

  

 <EMI ID=115.1> 


  
 <EMI ID=116.1>  

  
 <EMI ID=117.1> 

  

 <EMI ID=118.1> 
 

  
 <EMI ID=119.1>  

  

 <EMI ID=120.1> 


  
 <EMI ID=121.1> 

  
 <EMI ID=122.1>  

  

 <EMI ID=123.1> 


  
 <EMI ID=124.1>  <EMI ID=125.1> 

  
 <EMI ID=126.1>  

  

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 <EMI ID=128.1>  
 <EMI ID=129.1> 
 <EMI ID=130.1>   <EMI ID=131.1> 

  
 <EMI ID=132.1>   <EMI ID=133.1>  

  
 <EMI ID=134.1>   <EMI ID=135.1>   <EMI ID=136.1>  <EMI ID=137.1> 

  
 <EMI ID=138.1>  <EMI ID=139.1> 

  

 <EMI ID=140.1> 
 

  
 <EMI ID=141.1> 

  
 <EMI ID=142.1> 

  
 <EMI ID=143.1> 

  
 <EMI ID=144.1> 
 <EMI ID=145.1> 
  <EMI ID=146.1> 

  

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 <EMI ID=148.1>  

  
évaporée jusque siccité. On a repris le résidu par de

  
 <EMI ID=149.1> 

  
de façon à obtenir 'Bolide., Après la. filtration, on a ;

  
 <EMI ID=150.1> 

  
 <EMI ID=151.1> 

  
 <EMI ID=152.1> 

  
 <EMI ID=153.1> 

  

 <EMI ID=154.1> 


  
 <EMI ID=155.1> 

  
posés qui suivent: 

  
 <EMI ID=156.1>   <EMI ID=157.1> 

  
6néthy 1_7-&#65533;imidazo.le; 

  
 <EMI ID=158.1>   <EMI ID=159.1> 

  
 <EMI ID=160.1> 

  
 <EMI ID=161.1> 

  
 <EMI ID=162.1> 

  
 <EMI ID=163.1> 

  
 <EMI ID=164.1> 

  
 <EMI ID=165.1> 

  
 <EMI ID=166.1>   <EMI ID=167.1>  

  
 <EMI ID=168.1> 

  
 <EMI ID=169.1> 

  
 <EMI ID=170.1> 

  
 <EMI ID=171.1> 

  
 <EMI ID=172.1> 

  
 <EMI ID=173.1>  <EMI ID=174.1> 

  
 <EMI ID=175.1> 

  
 <EMI ID=176.1> 

  
 <EMI ID=177.1> 

  
 <EMI ID=178.1> 

  
 <EMI ID=179.1> 

  
 <EMI ID=180.1> 

  
qui suivent:  <EMI ID=181.1>  Analyse des éléments: 

  
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 <EMI ID=183.1> 

  
 <EMI ID=184.1> 

  
 <EMI ID=185.1> 

  
agitation.. On a agité le mélange réactionnel'pendant 

  
 <EMI ID=186.1> 

  
 <EMI ID=187.1> 

  
 <EMI ID=188.1> 

  
 <EMI ID=189.1> 

  
 <EMI ID=190.1> 

  
 <EMI ID=191.1> 

  
 <EMI ID=192.1> 



   <EMI ID = 1.1>

  
and their preparation <EMI ID = 2.1>

  

 <EMI ID = 3.1>


  
 <EMI ID = 4.1>

  
 <EMI ID = 5.1> <EMI ID = 6.1> <EMI ID = 7.1>

  
 <EMI ID = 8.1>

  
 <EMI ID = 9.1>

  
 <EMI ID = 10.1>

  
 <EMI ID = 11.1> <EMI ID = 12.1> <EMI ID = 13.1>

  
salts with nitric acid ^ The structural formulas of the compounds listed above given in accordance with their progressive number "appear in the following table:

  

 <EMI ID = 14.1>
 

  

 <EMI ID = 15.1>
 

  

 <EMI ID = 16.1>
 

  

 <EMI ID = 17.1>
 

  

 <EMI ID = 18.1>


  
can prepare compounds according to

  
 <EMI ID = 19.1>

  

 <EMI ID = 20.1>


  
 <EMI ID = 21.1>

  

 <EMI ID = 22.1>


  
 <EMI ID = 23.1> <EMI ID = 24.1> <EMI ID = 25.1>

  
 <EMI ID = 26.1> <EMI ID = 27.1> <EMI ID = 28.1>

  
 <EMI ID = 29.1>

  
 <EMI ID = 30.1> <EMI ID = 31.1>

  

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 <EMI ID = 33.1>

  
 <EMI ID = 34.1>

  
'&#65533;' &#65533; e, &#65533; &#65533; '&#65533;. &#65533;,.

  
 <EMI ID = 35.1> methyl or ethyl alcohol, for example "or by

  
 <EMI ID = 36.1>

  
 <EMI ID = 37.1>

  
 <EMI ID = 38.1>

  
 <EMI ID = 39.1>

  
 <EMI ID = 40.1>

  
reflux, during reaction periods which vary

  
 <EMI ID = 41.1> <EMI ID = 42.1> suitable lyser such as, for example, palladium,

  
 <EMI ID = 43.1>

  
 <EMI ID = 44.1>

  
the group formed by ethyl alcohol, 1 alcohol

  
 <EMI ID = 45.1>

  
 <EMI ID = 46.1>

  
 <EMI ID = 47.1>

  
 <EMI ID = 48.1> <EMI ID = 49.1>

  
 <EMI ID = 50.1>

  
 <EMI ID = 51.1>

  
a cation, for example an alkaline cation, from

  
 <EMI ID = 52.1>

  
 <EMI ID = 53.1>

  
 <EMI ID = 54.1>

  
 <EMI ID = 55.1>

  
hydride of an alkali metal, hydride <EMI ID = 56.1>

  
 <EMI ID = 57.1>

  
 <EMI ID = 58.1>

  
 <EMI ID = 59.1>

  
 <EMI ID = 60.1>

  
 <EMI ID = 61.1>

  
 <EMI ID = 62.1>

  
 <EMI ID = 63.1>

  
 <EMI ID = 64.1> <EMI ID = 65.1>
- process work for example. per treatment at <EMI ID = 66.1>

  
 <EMI ID = 67.1>

  
 <EMI ID = 68.1>

  

 <EMI ID = 69.1>


  
 <EMI ID = 70.1> <EMI ID = 71.1> <EMI ID = 72.1> <EMI ID = 73.1>

  
 <EMI ID = 74.1>

  
minimum inhibitory concentrations, vary from

  
 <EMI ID = 75.1>

  
 <EMI ID = 76.1>

  
 <EMI ID = 77.1>

  
We obtained in a similar way data

  
 <EMI ID = 78.1> <EMI ID = 79.1>

  
Pharmaceutical compositions containing

  
 <EMI ID = 80.1>

  
 <EMI ID = 81.1> <EMI ID = 82.1> <EMI ID = 83.1> <EMI ID = 84.1>

  
 <EMI ID = 85.1> <EMI ID = 86.1>

  
 <EMI ID = 87.1>

  
 <EMI ID = 88.1>

  
 <EMI ID = 89.1> <EMI ID = 90.1>

  
prepare the 'vaginal candles in the classic way.

  
 <EMI ID = 91.1>

  
 <EMI ID = 92.1>

  
 <EMI ID = 93.1>

  
 <EMI ID = 94.1>

  
 <EMI ID = 95.1>

  
 <EMI ID = 96.1>

  
 <EMI ID = 97.1>

  
 <EMI ID = 98.1>

  
sil lotion.

  
 <EMI ID = 99.1>

  
 <EMI ID = 100.1> <EMI ID = 101.1>

  
 <EMI ID = 102.1>

  
 <EMI ID = 103.1> <EMI ID = 104.1> <EMI ID = 105.1> <EMI ID = 106.1>

  
 <EMI ID = 107.1>

  

 <EMI ID = 108.1>


  
 <EMI ID = 109.1>. implementation of the same process:

  
 <EMI ID = 110.1>

  
 <EMI ID = 111.1>

  
 <EMI ID = 112.1>

  
 <EMI ID = 113.1>

  
 <EMI ID = 114.1>

  

 <EMI ID = 115.1>


  
 <EMI ID = 116.1>

  
 <EMI ID = 117.1>

  

 <EMI ID = 118.1>
 

  
 <EMI ID = 119.1>

  

 <EMI ID = 120.1>


  
 <EMI ID = 121.1>

  
 <EMI ID = 122.1>

  

 <EMI ID = 123.1>


  
 <EMI ID = 124.1> <EMI ID = 125.1>

  
 <EMI ID = 126.1>

  

 <EMI ID = 127.1>


  
 <EMI ID = 128.1>
 <EMI ID = 129.1>
 <EMI ID = 130.1> <EMI ID = 131.1>

  
 <EMI ID = 132.1> <EMI ID = 133.1>

  
 <EMI ID = 134.1> <EMI ID = 135.1> <EMI ID = 136.1> <EMI ID = 137.1>

  
 <EMI ID = 138.1> <EMI ID = 139.1>

  

 <EMI ID = 140.1>
 

  
 <EMI ID = 141.1>

  
 <EMI ID = 142.1>

  
 <EMI ID = 143.1>

  
 <EMI ID = 144.1>
 <EMI ID = 145.1>
  <EMI ID = 146.1>

  

 <EMI ID = 147.1>
 

  
 <EMI ID = 148.1>

  
evaporated to dryness. The residue was taken up by

  
 <EMI ID = 149.1>

  
so as to obtain 'Bolide., After the. filtration, we have;

  
 <EMI ID = 150.1>

  
 <EMI ID = 151.1>

  
 <EMI ID = 152.1>

  
 <EMI ID = 153.1>

  

 <EMI ID = 154.1>


  
 <EMI ID = 155.1>

  
posed as follows:

  
 <EMI ID = 156.1> <EMI ID = 157.1>

  
6nethy 1_7 - &#65533;imidazo.le;

  
 <EMI ID = 158.1> <EMI ID = 159.1>

  
 <EMI ID = 160.1>

  
 <EMI ID = 161.1>

  
 <EMI ID = 162.1>

  
 <EMI ID = 163.1>

  
 <EMI ID = 164.1>

  
 <EMI ID = 165.1>

  
 <EMI ID = 166.1> <EMI ID = 167.1>

  
 <EMI ID = 168.1>

  
 <EMI ID = 169.1>

  
 <EMI ID = 170.1>

  
 <EMI ID = 171.1>

  
 <EMI ID = 172.1>

  
 <EMI ID = 173.1> <EMI ID = 174.1>

  
 <EMI ID = 175.1>

  
 <EMI ID = 176.1>

  
 <EMI ID = 177.1>

  
 <EMI ID = 178.1>

  
 <EMI ID = 179.1>

  
 <EMI ID = 180.1>

  
that follow: <EMI ID = 181.1> Analysis of elements:

  
 <EMI ID = 182.1>

  
 <EMI ID = 183.1>

  
 <EMI ID = 184.1>

  
 <EMI ID = 185.1>

  
stirring. The reaction mixture was stirred during

  
 <EMI ID = 186.1>

  
 <EMI ID = 187.1>

  
 <EMI ID = 188.1>

  
 <EMI ID = 189.1>

  
 <EMI ID = 190.1>

  
 <EMI ID = 191.1>

  
 <EMI ID = 192.1>

Claims (1)

<EMI ID=193.1> <EMI ID = 193.1> <EMI ID=194.1> <EMI ID = 194.1> Pommade Ointment <EMI ID=195.1> <EMI ID = 195.1> <EMI ID=196.1> <EMI ID = 196.1> <EMI ID=197.1> <EMI ID = 197.1> <EMI ID=198.1> <EMI ID = 198.1> glycol 4000... glycol 4000 ... <EMI ID=199.1> <EMI ID = 199.1> <EMI ID=200.1> <EMI ID = 200.1> <EMI ID=201.1> <EMI ID = 201.1> <EMI ID=202.1> <EMI ID = 202.1> &#65533;&#65533;:DICATIC:jS &#65533; &#65533;: DICATIC: jS <EMI ID=203.1> <EMI ID = 203.1> <EMI ID=204.1> <EMI ID=205.1> <EMI ID = 204.1> <EMI ID = 205.1> 3 à 7 atomes de carbone, <EMI ID=206.1> 3 to 7 carbon atoms, <EMI ID = 206.1> <EMI ID=207.1> <EMI ID = 207.1> <EMI ID=208.1> <EMI ID = 208.1> <EMI ID=209.1> <EMI ID = 209.1> <EMI ID=210.1> <EMI ID=211.1> <EMI ID = 210.1> <EMI ID = 211.1> chacun des groupes Y qui peuvent 'être, identiques ou différents, est choisi dans le groupe formé par l'hydrogène, les each of the Y groups which may be the same or different is selected from the group consisting of hydrogen, <EMI ID=212.1> <EMI ID = 212.1> ainsi que les sels de ces composés acceptables en phar- as well as the pharmaceutically acceptable salts of these compounds. <EMI ID=213.1> <EMI ID=214.1> <EMI ID = 213.1> <EMI ID = 214.1> gène ou un groupe phényle non substitué et dans laquelle, gene or an unsubstituted phenyl group and in which, <EMI ID=215.1> <EMI ID = 215.1> - ou, lorsque Y représente un groupe phényle non substituée <EMI ID=216.1> - or, when Y represents an unsubstituted phenyl group <EMI ID = 216.1> tables en pharmacie humaine bu vétérinaire. tables in human pharmacy drunk veterinarian. <EMI ID=217.1> <EMI ID = 217.1> <EMI ID=218.1> <EMI ID = 218.1> <EMI ID=219.1> <EMI ID = 219.1> <EMI ID=220.1> <EMI ID=221.1> <EMI ID = 220.1> <EMI ID = 221.1> <EMI ID=222.1> <EMI ID = 222.1> pharmacie humain" ou vétérinaire. human "or veterinary pharmacy. <EMI ID=223.1> <EMI ID = 223.1> <EMI ID=224.1> <EMI ID = 224.1> <EMI ID=225.1> <EMI ID=226.1> <EMI ID = 225.1> <EMI ID = 226.1> par les substances suivantes: by the following substances: <EMI ID=227.1> <EMI ID = 227.1> -!n!&#65533;da=o&#65533;e&#65533; . -! n! &#65533; da = o &#65533; e &#65533; . <EMI ID=228.1> <EMI ID = 228.1> <EMI ID=229.1> <EMI ID=230.1> <EMI ID = 229.1> <EMI ID = 230.1> <EMI ID=231.1> ainsi que les sels de ces composés acceptables en <EMI ID = 231.1> as well as the salts of these compounds which are acceptable in <EMI ID=232.1> <EMI ID = 232.1> <EMI ID=233.1> <EMI ID = 233.1> par les substances suivantes: <EMI ID=234.1> by the following substances: <EMI ID = 234.1> <EMI ID=235.1> <EMI ID = 235.1> médecine humaine ou vétérinaire-... human or veterinary medicine -... <EMI ID=236.1> <EMI ID = 236.1> <EMI ID=237.1> <EMI ID = 237.1> <EMI ID=238.1> <EMI ID = 238.1> <EMI ID=239.1> <EMI ID=240.1> <EMI ID = 239.1> <EMI ID = 240.1> <EMI ID=241.1> <EMI ID = 241.1> <EMI ID=242.1> <EMI ID = 242.1> <EMI ID=243.1> <EMI ID = 243.1> tion 17 . avec un acide inorganique. tion 17. with an inorganic acid. <EMI ID=244.1> <EMI ID = 244.1> <EMI ID=245.1> <EMI ID = 245.1> <EMI ID=246.1> <EMI ID = 246.1> <EMI ID=247.1> <EMI ID = 247.1> <EMI ID=248.1> <EMI ID = 248.1> <EMI ID=249.1> <EMI ID = 249.1> <EMI ID=250.1> <EMI ID = 250.1> <EMI ID=251.1> <EMI ID = 251.1> dans laquelle <EMI ID=252.1> where <EMI ID = 252.1> <EMI ID=253.1> <EMI ID = 253.1> <EMI ID=254.1> <EMI ID=255.1> <EMI ID = 254.1> <EMI ID = 255.1>
BE0/195675A 1978-06-12 1979-06-11 NEW DERIVATIVES OF N-PHENETHYL IMIDAZOLE AND THEIR PREPARATION BE876897A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT24426/78A IT1096639B (en) 1978-06-12 1978-06-12 N-FENETILIMIDAZOLICI DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION

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AU (1) AU4746979A (en)
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IT (1) IT1096639B (en)
ZA (1) ZA792715B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194829A (en) * 1979-09-06 1984-10-19 Bristol Myers Co 1-phenethylimidazole derivatives;antibacterial and fungicidal compositions

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AU4746979A (en) 1979-12-20
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ZA792715B (en) 1980-06-25
IT1096639B (en) 1985-08-26

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