BE876039A - Nouvelles 4-quinolinylaminobenzoylpiperazines, leur procede de preparation - Google Patents

Nouvelles 4-quinolinylaminobenzoylpiperazines, leur procede de preparation

Info

Publication number
BE876039A
BE876039A BE0/194991A BE194991A BE876039A BE 876039 A BE876039 A BE 876039A BE 0/194991 A BE0/194991 A BE 0/194991A BE 194991 A BE194991 A BE 194991A BE 876039 A BE876039 A BE 876039A
Authority
BE
Belgium
Prior art keywords
quinolinylaminobenzoylpiperazines
news
preparation process
preparation
Prior art date
Application number
BE0/194991A
Other languages
English (en)
French (fr)
Inventor
J Mccall
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BE876039A publication Critical patent/BE876039A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
BE0/194991A 1978-05-05 1979-05-04 Nouvelles 4-quinolinylaminobenzoylpiperazines, leur procede de preparation BE876039A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/903,082 US4167567A (en) 1978-05-05 1978-05-05 Antihypertensive 4-aminoquinolines

Publications (1)

Publication Number Publication Date
BE876039A true BE876039A (fr) 1979-11-05

Family

ID=25416910

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/194991A BE876039A (fr) 1978-05-05 1979-05-04 Nouvelles 4-quinolinylaminobenzoylpiperazines, leur procede de preparation

Country Status (16)

Country Link
US (1) US4167567A (de)
JP (1) JPS54145683A (de)
AU (1) AU522635B2 (de)
BE (1) BE876039A (de)
CA (1) CA1082707A (de)
CH (1) CH642964A5 (de)
DE (1) DE2914492A1 (de)
ES (1) ES480190A1 (de)
FR (1) FR2424913A1 (de)
GB (1) GB2021567B (de)
HK (1) HK60085A (de)
IT (1) IT1192349B (de)
NL (1) NL7902907A (de)
SE (1) SE440352B (de)
SG (1) SG38285G (de)
ZA (1) ZA791809B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8424979D0 (en) * 1984-10-03 1984-11-07 Wyeth John & Brother Ltd Benzenesulphonamide derivatives
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
GB8505430D0 (en) * 1985-03-02 1985-04-03 Wyeth John & Brother Ltd Benzamide derivatives
WO1986005489A1 (en) * 1985-03-13 1986-09-25 The Upjohn Company Process for 4-amino quinolines
US5212182A (en) * 1990-10-03 1993-05-18 American Home Products Corpooration Substituted quinolinyl- and naphthalenylbenzamides or benzylamines and related compounds useful as analgesics
US5438064A (en) * 1991-12-23 1995-08-01 American Home Products Corporation Derivatives of 4-anilinoquinoline-3-carboxamide as analgesic agents
IL115420A0 (en) 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
GB9516709D0 (en) * 1995-08-15 1995-10-18 Zeneca Ltd Medicament
US6313127B1 (en) 1996-02-02 2001-11-06 Zeneca Limited Heterocyclic compounds useful as pharmaceutical agents
GB9602166D0 (en) 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
CZ45699A3 (cs) * 1996-08-14 1999-05-12 Zeneca Limited Substituované deriváty pyrimidinu, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
US6440972B1 (en) 1997-02-13 2002-08-27 Zeneca Limited Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
DE69815509T2 (de) 1997-02-13 2004-05-13 Astrazeneca Ab Heterozyklische verbindungen die als oxido-squalen-zyklase-inhibitoren anwendung finden
GB9715895D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
US5922203A (en) * 1997-10-07 1999-07-13 Hydranautics Amine monomers and their use in preparing interfacially synthesized membranes for reverse osmosis and nanofiltration
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
US6464873B1 (en) 1999-06-15 2002-10-15 Hydranautics Interfacially polymerized, bipiperidine-polyamide membranes for reverse osmosis and/or nanofiltration and process for making the same
US7842696B2 (en) * 2007-06-21 2010-11-30 Forest Laboratories Holdings Limited Piperazine derivatives as inhibitors of stearoyl-CoA desaturase
US9795928B2 (en) 2014-06-24 2017-10-24 Nano And Advanced Materials Institute Limited Stepwise interfacial polymerization technique with different reagent solution designs to prepare hollow fiber nanofiltration membrane composites

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
BE754586A (fr) * 1969-08-08 1971-02-08 Upjohn Co Preparations pharmaceutiques a base de p-(4-quinolylamino) benzamide etleur utilisation
ZA742410B (en) * 1973-05-04 1975-04-30 Upjohn Co A new chemical process for preparing 2-,3-and 4-(4-quinolyl)-aminobenzamides
ZA743269B (en) * 1973-06-15 1975-05-28 Upjohn Co Anti-hypertensive compounds
US4025629A (en) * 1974-01-07 1977-05-24 The Upjohn Company P-(trifluoromethylquinolylamino)benzamides, pharmaceutical dosage forms and method of treatment

Also Published As

Publication number Publication date
HK60085A (en) 1985-08-16
DE2914492A1 (de) 1979-11-08
US4167567A (en) 1979-09-11
FR2424913B1 (de) 1983-05-20
GB2021567A (en) 1979-12-05
JPS54145683A (en) 1979-11-14
SG38285G (en) 1985-11-15
CA1082707A (en) 1980-07-29
IT7922086A0 (it) 1979-04-23
NL7902907A (nl) 1979-11-07
ZA791809B (en) 1980-05-28
AU522635B2 (en) 1982-06-17
CH642964A5 (de) 1984-05-15
SE440352B (sv) 1985-07-29
ES480190A1 (es) 1980-02-01
SE7903820L (sv) 1979-11-06
GB2021567B (en) 1982-09-02
FR2424913A1 (fr) 1979-11-30
IT1192349B (it) 1988-03-31
AU4667679A (en) 1979-11-08

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: THE UPJOHN CY

Effective date: 19880531