BE873136A - Procede de preparation de la vincadifformine - Google Patents

Procede de preparation de la vincadifformine

Info

Publication number
BE873136A
BE873136A BE192612A BE192612A BE873136A BE 873136 A BE873136 A BE 873136A BE 192612 A BE192612 A BE 192612A BE 192612 A BE192612 A BE 192612A BE 873136 A BE873136 A BE 873136A
Authority
BE
Belgium
Prior art keywords
vincadifformin
preparation
Prior art date
Application number
BE192612A
Other languages
English (en)
French (fr)
Original Assignee
Omnium Chimique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnium Chimique Sa filed Critical Omnium Chimique Sa
Publication of BE873136A publication Critical patent/BE873136A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/313—Compounds having groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
BE192612A 1977-12-29 1978-12-28 Procede de preparation de la vincadifformine BE873136A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/865,657 US4154943A (en) 1977-12-29 1977-12-29 Preparation of vincadifformine

Publications (1)

Publication Number Publication Date
BE873136A true BE873136A (fr) 1979-06-28

Family

ID=25345973

Family Applications (1)

Application Number Title Priority Date Filing Date
BE192612A BE873136A (fr) 1977-12-29 1978-12-28 Procede de preparation de la vincadifformine

Country Status (9)

Country Link
US (1) US4154943A (cg-RX-API-DMAC7.html)
JP (1) JPS5498800A (cg-RX-API-DMAC7.html)
BE (1) BE873136A (cg-RX-API-DMAC7.html)
CA (1) CA1098903A (cg-RX-API-DMAC7.html)
ES (1) ES476504A1 (cg-RX-API-DMAC7.html)
FR (1) FR2413391A1 (cg-RX-API-DMAC7.html)
GB (1) GB2011899B (cg-RX-API-DMAC7.html)
HU (1) HU180905B (cg-RX-API-DMAC7.html)
IT (1) IT1109011B (cg-RX-API-DMAC7.html)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4283536A (en) * 1977-12-29 1981-08-11 University Of Vermont Preparation of vincadifformine and related derivatives
US4267330A (en) * 1978-08-24 1981-05-12 Omnium Chimique Societe Anonyme Process for the synthesis of vincadifformine and related derivatives
FR2434166A2 (fr) * 1978-08-24 1980-03-21 Omnium Chimique Sa Procede de preparation de vincadifformine et derives similaires
US4220774A (en) * 1978-10-26 1980-09-02 Omnium Chimique Vincadifformine synthesis process
US4428880A (en) 1981-05-04 1984-01-31 S.A. Omnichem Azepino[4,5-d]indole derivatives and preparation thereof
US4362739A (en) * 1981-05-04 1982-12-07 S.A. Omnichem Pyrrolo(2,3-d)carbazole derivatives, compositions and use
LU85894A1 (fr) * 1985-05-10 1986-12-05 Omnichem Sa Derives de 1,2,3,4,5,6-hexahydro-azepino (4,5-b) indole leur preparation,composes intermediaires,et leur application en therapeutique
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
AR024158A1 (es) 1999-06-01 2002-09-04 Smithkline Beecham Corp Compuestos antibacterianos
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
HK1049656A1 (zh) * 1999-10-08 2003-05-23 Smithkline Beecham Corporation Fab i抑制剂
DE60230934D1 (de) * 2001-04-06 2009-03-05 Affinium Pharm Inc Fab-i-inhibitoren
CA2508792C (en) * 2002-12-06 2013-02-05 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
JP4880448B2 (ja) 2003-03-17 2012-02-22 アフィナム ファーマシューティカルズ，インコーポレーテッド 複数の抗生物質を含む組成物、及びそれを用いる方法
DK1828167T3 (da) * 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
US20090156578A1 (en) * 2005-12-05 2009-06-18 PAULS Henry 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
US20130178618A1 (en) 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same
SMT201900411T1 (it) 2012-06-19 2019-09-09 Debiopharm Int Sa Derivati di profaramci di (e)-n-metil-n-((3-metilbenzofuran-2-il)metil -3-(7-osso-5,6,7,8-tetraidro-1,8-naftiridin-3-il)acrilammide
HUE052140T2 (hu) 2016-02-26 2021-04-28 Debiopharm Int Sa Diabéteszes lábfertõzések kezelésére szolgáló gyógyszer
CN107216328A (zh) * 2017-07-06 2017-09-29 贵州医科大学 一种α‑卡波林类化合物的合成方法
JP7383715B2 (ja) 2019-02-14 2023-11-20 デバイオファーム インターナショナル エス．エー． アファビシン製剤、その作製方法及びその使用
EA202290048A1 (ru) 2019-06-14 2022-03-10 Дебиофарм Интернэшнл C.A. Лекарственное средство и его применение для лечения бактериальных инфекций, связанных с биопленкой
US12116372B1 (en) 2023-12-14 2024-10-15 William Allen Boulanger Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE811614A (en) 1974-02-27 1974-06-17 (-) Vincadifformine prodn. - by hemisynthesis starting from vindolinine which is obtd. from catharantus roseus

Also Published As

Publication number Publication date
ES476504A1 (es) 1979-11-16
FR2413391A1 (fr) 1979-07-27
JPS6215555B2 (cg-RX-API-DMAC7.html) 1987-04-08
GB2011899B (en) 1982-05-26
IT1109011B (it) 1985-12-16
HU180905B (en) 1983-05-30
GB2011899A (en) 1979-07-18
IT7809692A0 (it) 1978-12-29
JPS5498800A (en) 1979-08-03
CA1098903A (en) 1981-04-07
FR2413391B1 (cg-RX-API-DMAC7.html) 1983-08-05
US4154943A (en) 1979-05-15

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: OMNIUM CHIMIQUE S.A.

Effective date: 19931231