BE872956A - Polyfluorohydroxyisopropyl carbostyriles bicycliques et tricycliques antihypertensifs,leur preparation et compositions pharmaceutiques les contenant - Google Patents

Polyfluorohydroxyisopropyl carbostyriles bicycliques et tricycliques antihypertensifs,leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
BE872956A
BE872956A BE192471A BE192471A BE872956A BE 872956 A BE872956 A BE 872956A BE 192471 A BE192471 A BE 192471A BE 192471 A BE192471 A BE 192471A BE 872956 A BE872956 A BE 872956A
Authority
BE
Belgium
Prior art keywords
polyfluorohydroxyisopropyl
carbostyriles
antihypertensifs
tricyclic
bicyclic
Prior art date
Application number
BE192471A
Other languages
English (en)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of BE872956A publication Critical patent/BE872956A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE192471A 1977-12-22 1978-12-21 Polyfluorohydroxyisopropyl carbostyriles bicycliques et tricycliques antihypertensifs,leur preparation et compositions pharmaceutiques les contenant BE872956A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/863,269 US4251534A (en) 1977-12-22 1977-12-22 Antihypertensive polyfluorohydroxyisopropyl bicyclic and tricyclic carbostyrils

Publications (1)

Publication Number Publication Date
BE872956A true BE872956A (fr) 1979-06-21

Family

ID=25340730

Family Applications (1)

Application Number Title Priority Date Filing Date
BE192471A BE872956A (fr) 1977-12-22 1978-12-21 Polyfluorohydroxyisopropyl carbostyriles bicycliques et tricycliques antihypertensifs,leur preparation et compositions pharmaceutiques les contenant

Country Status (11)

Country Link
US (1) US4251534A (fr)
JP (1) JPS5498780A (fr)
BE (1) BE872956A (fr)
CA (1) CA1099712A (fr)
DE (1) DE2854727A1 (fr)
DK (1) DK574978A (fr)
FR (1) FR2412533A1 (fr)
GB (1) GB2010821B (fr)
IT (1) IT1102419B (fr)
LU (1) LU80720A1 (fr)
NL (1) NL7812422A (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499108A (en) * 1983-06-08 1985-02-12 Schering Corporation Stable pleasant-tasting albuterol sulfate pharmaceutical formulations
US5622965A (en) * 1993-03-12 1997-04-22 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-ones and the use thereof as excitatory amino acid and glycine receptor antagonists
US6316503B1 (en) 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
JP4434744B2 (ja) * 2002-01-30 2010-03-17 アムジェン インコーポレイテッド アリールスルホンアミドベンジル化合物
US7112606B2 (en) * 2002-01-30 2006-09-26 Amgen Inc. Heterocyclic arylsulfonamidobenzylic compounds
MXPA06001566A (es) * 2003-08-12 2006-05-15 Amgen Inc Compuestos arilsulfonamidobencilicos.
GB201721964D0 (en) * 2017-12-27 2018-02-07 Bp Oil Int Methods for preparing fuel additives
GB201721967D0 (en) * 2017-12-27 2018-02-07 Bp Oil Int Methods for preparing fuel additives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR980098A (fr) * 1948-12-10 1951-05-08 Poignée protectrice à usages ménagers
US3178348A (en) * 1961-02-08 1965-04-13 Norwich Pharma Co Hypotensive quinolines
DE1216878B (de) * 1963-04-02 1966-05-18 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von coronargefaesserweiternden Derivaten des 7-Hydroxy-2-oxo-1, 2-dihydrochinolins
US4058612A (en) * 1974-12-02 1977-11-15 Schering Corporation 6-(Polyhaloisopropyl)quinazoline-2,4-diones
IE45227B1 (en) * 1976-06-24 1982-07-14 Du Pont Carbostyrils

Also Published As

Publication number Publication date
FR2412533B1 (fr) 1981-10-02
IT7831170A0 (it) 1978-12-21
LU80720A1 (fr) 1980-01-22
NL7812422A (nl) 1979-06-26
JPS5498780A (en) 1979-08-03
GB2010821B (en) 1982-08-11
CA1099712A (fr) 1981-04-21
FR2412533A1 (fr) 1979-07-20
US4251534A (en) 1981-02-17
DK574978A (da) 1979-06-23
DE2854727A1 (de) 1979-06-28
IT1102419B (it) 1985-10-07
GB2010821A (en) 1979-07-04

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