BE866661A - Procede de preparation de n-alkyl-n-iminomethyl-thienamycines et leur utilisation - Google Patents

Procede de preparation de n-alkyl-n-iminomethyl-thienamycines et leur utilisation

Info

Publication number
BE866661A
BE866661A BE187351A BE187351A BE866661A BE 866661 A BE866661 A BE 866661A BE 187351 A BE187351 A BE 187351A BE 187351 A BE187351 A BE 187351A BE 866661 A BE866661 A BE 866661A
Authority
BE
Belgium
Prior art keywords
thienamycines
iminomethyl
alkyl
preparation
Prior art date
Application number
BE187351A
Other languages
English (en)
French (fr)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of BE866661A publication Critical patent/BE866661A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE187351A 1977-05-05 1978-05-03 Procede de preparation de n-alkyl-n-iminomethyl-thienamycines et leur utilisation BE866661A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79397577A 1977-05-05 1977-05-05

Publications (1)

Publication Number Publication Date
BE866661A true BE866661A (fr) 1978-11-03

Family

ID=25161306

Family Applications (1)

Application Number Title Priority Date Filing Date
BE187351A BE866661A (fr) 1977-05-05 1978-05-03 Procede de preparation de n-alkyl-n-iminomethyl-thienamycines et leur utilisation

Country Status (13)

Country Link
JP (1) JPS53137993A (sv)
BE (1) BE866661A (sv)
CH (1) CH637962A5 (sv)
DE (1) DE2819453A1 (sv)
DK (1) DK170778A (sv)
ES (1) ES469426A1 (sv)
FR (1) FR2389626B1 (sv)
GB (1) GB1604275A (sv)
IE (1) IE46873B1 (sv)
IT (1) IT1104190B (sv)
LU (1) LU79598A1 (sv)
NL (1) NL7804229A (sv)
SE (1) SE436569B (sv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
AU512383B2 (en) * 1975-11-21 1980-10-09 Merck & Co., Inc. Thinenamycin derivatives

Also Published As

Publication number Publication date
CH637962A5 (en) 1983-08-31
ES469426A1 (es) 1980-02-01
JPS53137993A (en) 1978-12-01
IT1104190B (it) 1985-10-21
DK170778A (da) 1979-01-15
FR2389626B1 (sv) 1980-06-20
FR2389626A1 (sv) 1978-12-01
GB1604275A (en) 1981-12-09
DE2819453C2 (sv) 1993-02-25
DE2819453A1 (de) 1978-11-09
IE780849L (en) 1978-11-05
LU79598A1 (fr) 1979-02-02
JPH0260678B2 (sv) 1990-12-17
IE46873B1 (en) 1983-10-19
SE436569B (sv) 1985-01-07
SE7804447L (sv) 1978-11-06
NL7804229A (nl) 1978-11-07
IT7849176A0 (it) 1978-05-03

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: MERCK & CO. INC.

Effective date: 19930531