BE866252A - Derives de mercaptoalkylsulfonyl proline et composes apparentes - Google Patents
Derives de mercaptoalkylsulfonyl proline et composes apparentesInfo
- Publication number
- BE866252A BE866252A BE187010A BE187010A BE866252A BE 866252 A BE866252 A BE 866252A BE 187010 A BE187010 A BE 187010A BE 187010 A BE187010 A BE 187010A BE 866252 A BE866252 A BE 866252A
- Authority
- BE
- Belgium
- Prior art keywords
- mercaptoalkylsulfonyl
- related compounds
- proline derivatives
- proline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/789,466 US4070361A (en) | 1977-04-21 | 1977-04-21 | Mercaptoalkylsulfonyl proline and pipecolic acid and esters thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE866252A true BE866252A (fr) | 1978-08-14 |
Family
ID=25147726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE187010A BE866252A (fr) | 1977-04-21 | 1978-04-21 | Derives de mercaptoalkylsulfonyl proline et composes apparentes |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4070361A (sv) |
| JP (1) | JPS53132560A (sv) |
| AU (1) | AU519234B2 (sv) |
| BE (1) | BE866252A (sv) |
| CA (1) | CA1104571A (sv) |
| DE (1) | DE2817593A1 (sv) |
| DK (1) | DK173778A (sv) |
| FR (1) | FR2387954A1 (sv) |
| GB (1) | GB1595123A (sv) |
| HU (1) | HU174845B (sv) |
| IT (1) | IT7848808A0 (sv) |
| NL (1) | NL7803769A (sv) |
| NO (1) | NO781392L (sv) |
| SE (1) | SE7804553L (sv) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4199512A (en) * | 1976-05-10 | 1980-04-22 | E. R. Squibb & Sons, Inc. | Compounds for alleviating hypertension |
| US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
| US4241076A (en) * | 1978-02-21 | 1980-12-23 | E. R. Squibb & Sons, Inc. | Halogenated substituted mercaptoacylamino acids |
| US4154934A (en) * | 1978-08-11 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Mercaptoacylamino derivatives of heterocyclic carboxylic acids |
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| US4690938A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| US4690939A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| US4698356A (en) * | 1979-08-14 | 1987-10-06 | University Of Miami | Anti-hypertensive agents |
| US4690940A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| US4698355A (en) * | 1979-08-14 | 1987-10-06 | University Of Miami | Anti-hypertensive agents |
| US4690937A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| US4695577A (en) * | 1979-08-14 | 1987-09-22 | University Of Miami | Anti-hypertensive agents |
| US4198515A (en) * | 1978-12-08 | 1980-04-15 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids |
| GB2065643B (en) * | 1979-12-13 | 1983-08-24 | Kanegafuchi Chemical Ind | Optically active n-mercaptoalkanoylamino acids |
| US4690936A (en) * | 1980-03-05 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| US4734420A (en) * | 1980-03-05 | 1988-03-29 | University Of Miami | Anti-hypertensive agents |
| US4552889A (en) * | 1983-06-09 | 1985-11-12 | Eli Lilly And Company | 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US5874449A (en) * | 1996-12-31 | 1999-02-23 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of heterocyclic thioesters |
| JP2002515051A (ja) | 1996-12-31 | 2002-05-21 | ジーピーアイ エヌアイエル ホールディングス インコーポレイテッド | ヘテロ環式チオエステルのｎ−結合スルホンアミド |
| US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
| JP2002516904A (ja) | 1998-06-03 | 2002-06-11 | ジーピーアイ ニル ホールディングス インコーポレイテッド | Ｎ−複素環式カルボン酸またはカルボン酸等配電子体のｎ−結合スルホンアミド |
| US7338976B1 (en) | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
| US6339101B1 (en) | 1998-08-14 | 2002-01-15 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders |
| US6335348B1 (en) | 1998-08-14 | 2002-01-01 | Gpi Nil Holdings, Inc. | Nitrogen-containing linear and azepinyl/ compositions and uses for vision and memory disorders |
| US6506788B1 (en) | 1998-08-14 | 2003-01-14 | Gpi Nil Holdings, Inc. | N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders |
| US6395758B1 (en) | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
| US6218423B1 (en) | 1998-08-14 | 2001-04-17 | Gpi Nil Holdings, Inc. | Pyrrolidine derivatives for vision and memory disorders |
| US6384056B1 (en) | 1998-08-14 | 2002-05-07 | Gpi Nil Holdings, Inc. | Heterocyclic thioesters or ketones for vision and memory disorders |
| US6399648B1 (en) | 1998-08-14 | 2002-06-04 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders |
| US6376517B1 (en) | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
| US6337340B1 (en) | 1998-08-14 | 2002-01-08 | Gpi Nil Holdings, Inc. | Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders |
| US6333340B1 (en) | 1998-08-14 | 2001-12-25 | Gpi Nil Holdings, Inc. | Small molecule sulfonamides for vision and memory disorders |
| US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
| US6300341B1 (en) | 1998-09-30 | 2001-10-09 | The Procter & Gamble Co. | 2-substituted heterocyclic sulfonamides |
| US6307049B1 (en) | 1998-09-30 | 2001-10-23 | The Procter & Gamble Co. | Heterocyclic 2-substituted ketoamides |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3086974A (en) * | 1957-06-05 | 1963-04-23 | Bayer Ag | Phosphoric acid, thionophosphoric acid, phosphonic acid, thiophosphonic acid, phosphinic acid and thionophosphinic acid derivatives of alkylsulfonamides |
| US3453312A (en) * | 1966-04-27 | 1969-07-01 | Merck & Co Inc | (beta - (substituted-thio) - acylphenoxy)-alkanoic acids and (beta-(substitutedthio) acylphenylmercapto) alkanoic acids and derivatives thereof |
| GB1380009A (en) * | 1972-08-12 | 1975-01-08 | Pfizer Ltd | Cyclic derivatives of 1,4-benzene disulphonamide |
-
1977
- 1977-04-21 US US05/789,466 patent/US4070361A/en not_active Expired - Lifetime
-
1978
- 1978-03-22 CA CA299,478A patent/CA1104571A/en not_active Expired
- 1978-03-29 AU AU34561/78A patent/AU519234B2/en not_active Expired
- 1978-03-30 GB GB12505/78A patent/GB1595123A/en not_active Expired
- 1978-04-04 FR FR7809958A patent/FR2387954A1/fr active Granted
- 1978-04-07 IT IT7848808A patent/IT7848808A0/it unknown
- 1978-04-10 NL NL7803769A patent/NL7803769A/xx not_active Application Discontinuation
- 1978-04-20 HU HU78SU974A patent/HU174845B/hu unknown
- 1978-04-20 NO NO781392A patent/NO781392L/no unknown
- 1978-04-20 DK DK173778A patent/DK173778A/da active IP Right Grant
- 1978-04-20 SE SE7804553A patent/SE7804553L/sv unknown
- 1978-04-21 DE DE19782817593 patent/DE2817593A1/de not_active Withdrawn
- 1978-04-21 JP JP4831078A patent/JPS53132560A/ja active Pending
- 1978-04-21 BE BE187010A patent/BE866252A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2387954A1 (fr) | 1978-11-17 |
| US4070361A (en) | 1978-01-24 |
| FR2387954B1 (sv) | 1981-08-21 |
| IT7848808A0 (it) | 1978-04-07 |
| DK173778A (da) | 1978-10-22 |
| JPS53132560A (en) | 1978-11-18 |
| GB1595123A (en) | 1981-08-05 |
| CA1104571A (en) | 1981-07-07 |
| NO781392L (no) | 1978-10-24 |
| HU174845B (hu) | 1980-03-28 |
| AU3456178A (en) | 1979-10-04 |
| AU519234B2 (en) | 1981-11-19 |
| NL7803769A (nl) | 1978-10-24 |
| SE7804553L (sv) | 1978-10-22 |
| DE2817593A1 (de) | 1978-10-26 |
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