BE860709A - Nouveaux derives substitues de 0-phenylenediamine, leur procede de preparation et medicament les contenant - Google Patents

Nouveaux derives substitues de 0-phenylenediamine, leur procede de preparation et medicament les contenant

Info

Publication number
BE860709A
BE860709A BE182531A BE182531A BE860709A BE 860709 A BE860709 A BE 860709A BE 182531 A BE182531 A BE 182531A BE 182531 A BE182531 A BE 182531A BE 860709 A BE860709 A BE 860709A
Authority
BE
Belgium
Prior art keywords
phenylenediamine
preparation
product containing
medicinal product
new substitute
Prior art date
Application number
BE182531A
Other languages
English (en)
French (fr)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BE860709A publication Critical patent/BE860709A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/33—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring
    • C07C323/35—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group
    • C07C323/37—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group the sulfur atom of the sulfide group being further bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE182531A 1976-11-11 1977-11-10 Nouveaux derives substitues de 0-phenylenediamine, leur procede de preparation et medicament les contenant BE860709A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762651467 DE2651467A1 (de) 1976-11-11 1976-11-11 Substituierte o-phenylendiaminderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
BE860709A true BE860709A (fr) 1978-05-10

Family

ID=5992911

Family Applications (1)

Application Number Title Priority Date Filing Date
BE182531A BE860709A (fr) 1976-11-11 1977-11-10 Nouveaux derives substitues de 0-phenylenediamine, leur procede de preparation et medicament les contenant

Country Status (18)

Country Link
US (1) US4246260A (da)
JP (1) JPS5363348A (da)
AR (1) AR217659A1 (da)
AU (1) AU509753B2 (da)
BE (1) BE860709A (da)
CH (1) CH631436A5 (da)
DE (1) DE2651467A1 (da)
DK (1) DK498977A (da)
ES (1) ES464013A1 (da)
FI (1) FI62830C (da)
FR (1) FR2370727A1 (da)
GB (1) GB1571148A (da)
HU (1) HU180660B (da)
NL (1) NL7712301A (da)
NZ (1) NZ185643A (da)
PH (1) PH14110A (da)
SE (1) SE7712733L (da)
ZA (1) ZA776716B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217358A (en) 1979-04-18 1980-08-12 E. R. Squibb & Sons, Inc. Substituted phenylguanidines and method

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293569A (en) * 1978-05-12 1981-10-06 E. R. Squibb & Sons, Inc. Substituted phenylguanindines and method
US4348406A (en) * 1980-10-20 1982-09-07 Schering Corporation Novel guanidine derivatives
US4328241A (en) * 1981-07-20 1982-05-04 E. R. Squibb & Sons, Inc. Substituted phenylguanidines and method
US4701447A (en) * 1983-09-23 1987-10-20 Schering Corporation N-((2-nitro)phenyl)-N' (organic acid) guanidine anthelmintics
US4723029A (en) * 1983-09-23 1988-02-02 Schering Corporation Organic acid-substituted guanidine anthelmintics
DE102018212006B3 (de) * 2018-07-18 2019-10-31 Universität Greifswald Thioether als Modulatoren von Kv7.2/Kv7.3-Kanälen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6568736D0 (pt) * 1964-04-09 1973-08-14 Drug Inc Sterling Processo para preparar uma bisguanida
BE758607A (fr) * 1969-11-06 1971-05-06 Bayer Ag Nouvelles amidophenylguanidines, leur procede de preparation etleur application comme fongicides
FR2109284A6 (da) * 1970-04-09 1972-05-26 Rhone Poulenc Sa
FR2108835A1 (en) * 1970-10-09 1972-05-26 Rhone Poulenc Sa Fungicidal guanidines from o phenylenediamine
DE2109454A1 (en) * 1971-02-27 1972-09-14 Farbenfabriken Bayer Ag, 5090 Leverkusen Fungicidal n-(2-acylaminophenyl)-n,n-bis(alkoxycarbonyl)-guanidines - from 2-acrylaminoanilines and s-alkyl n,n-bis(alkoxycarbonyl) isothiazole
DE2250911A1 (de) * 1972-10-18 1974-04-25 Bayer Ag Phenylguanidin-derivate, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IN142490B (da) * 1974-05-15 1977-07-16 Bayer Ag
US4024176A (en) * 1974-05-15 1977-05-17 Bayer Aktiengesellschaft Substituted phenylguanidines and processes for their preparation and use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217358A (en) 1979-04-18 1980-08-12 E. R. Squibb & Sons, Inc. Substituted phenylguanidines and method

Also Published As

Publication number Publication date
US4246260A (en) 1981-01-20
ES464013A1 (es) 1978-07-16
FI773368A (fi) 1978-05-12
HU180660B (en) 1983-04-29
FI62830B (fi) 1982-11-30
FR2370727A1 (fr) 1978-06-09
DE2651467A1 (de) 1978-05-18
SE7712733L (sv) 1978-05-12
GB1571148A (en) 1980-07-09
FR2370727B1 (da) 1981-02-13
NZ185643A (en) 1979-08-31
AU509753B2 (en) 1980-05-22
AR217659A1 (es) 1980-04-15
PH14110A (en) 1981-02-26
NL7712301A (nl) 1978-05-16
CH631436A5 (de) 1982-08-13
ZA776716B (en) 1978-08-30
DK498977A (da) 1978-05-12
FI62830C (fi) 1983-03-10
AU3050877A (en) 1979-05-17
JPS5363348A (en) 1978-06-06

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BAYER A.G.

Effective date: 19841110