BE849794A - Derives de carbostyrile et leur procede de preparation - Google Patents

Derives de carbostyrile et leur procede de preparation

Info

Publication number
BE849794A
BE849794A BE173581A BE173581A BE849794A BE 849794 A BE849794 A BE 849794A BE 173581 A BE173581 A BE 173581A BE 173581 A BE173581 A BE 173581A BE 849794 A BE849794 A BE 849794A
Authority
BE
Belgium
Prior art keywords
preparation process
carbostyrile
derivatives
carbostyrile derivatives
preparation
Prior art date
Application number
BE173581A
Other languages
English (en)
French (fr)
Inventor
K Nakagawa
E Yo
Sh Yoshizaki
Sh Tafaba
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE849794A publication Critical patent/BE849794A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
    • C07D215/32Esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
BE173581A 1976-10-08 1976-12-23 Derives de carbostyrile et leur procede de preparation BE849794A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51121423A JPS609713B2 (ja) 1976-10-08 1976-10-08 カルボスチリル誘導体

Publications (1)

Publication Number Publication Date
BE849794A true BE849794A (fr) 1977-04-15

Family

ID=14810767

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173581A BE849794A (fr) 1976-10-08 1976-12-23 Derives de carbostyrile et leur procede de preparation

Country Status (10)

Country Link
US (1) US4223137A (ja)
JP (1) JPS609713B2 (ja)
BE (1) BE849794A (ja)
CA (1) CA1074801A (ja)
CH (1) CH618431A5 (ja)
DE (1) DE2658544C2 (ja)
FR (1) FR2378521A1 (ja)
GB (1) GB1540628A (ja)
NL (1) NL174041C (ja)
SE (1) SE434395B (ja)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653323B2 (en) 2001-11-13 2003-11-25 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US6670376B1 (en) 2001-11-13 2003-12-30 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US6747043B2 (en) 2002-05-28 2004-06-08 Theravance, Inc. Alkoxy aryl β2 adrenergic receptor agonists
US7399863B2 (en) 2003-09-22 2008-07-15 Theravance, Inc. Amino-substituted ethylamino β2 adrenergic receptor agonists
US7402673B2 (en) 2004-06-03 2008-07-22 Theravance, Inc. Diamine β2 adrenergic receptor agonists
US7566785B2 (en) 2004-09-10 2009-07-28 Theravance, Inc. Amidine substituted aryl aniline compounds
US7582765B2 (en) 2003-05-08 2009-09-01 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US7622467B2 (en) 2004-01-12 2009-11-24 Theravance, Inc. Aryl aniline derivatives as β2 adrenergic receptor agonists

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
US4322425A (en) * 1980-03-14 1982-03-30 Otsuka Pharmaceutical Co., Ltd. Compositions for treating glaucoma
FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
US4456757A (en) * 1981-03-20 1984-06-26 Asahi Kasei Kogyo Kabushiki Kaisha Isoquinolinesulfonyl derivatives and process for the preparation thereof
EP0062001B1 (de) * 1981-03-24 1987-05-27 Ciba-Geigy Ag Acyl-chinolinonderivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate und ihre Verwendung
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
JPS60173736U (ja) * 1984-04-25 1985-11-18 株式会社昭和製作所 緩衝器用サブタンク
JPS61191767A (ja) * 1985-02-20 1986-08-26 辻本 夘太郎 植物張り家屋
JPS62113672A (ja) * 1985-11-12 1987-05-25 本田技研工業株式会社 リヤクツシヨン用リザ−ブタンク
JPS6348401U (ja) * 1986-09-17 1988-04-01
US4687776A (en) * 1986-10-24 1987-08-18 Warner-Lambert Company Drug stabilization
JPS63106132A (ja) * 1986-10-24 1988-05-11 Mazda Motor Corp 車両のサスペンシヨン装置
JPS6374545U (ja) * 1986-10-31 1988-05-18
JPH0517463Y2 (ja) * 1987-07-21 1993-05-11
JPS6417047U (ja) * 1987-07-21 1989-01-27
JPH0518510Y2 (ja) * 1987-12-28 1993-05-17
US4894219A (en) * 1988-03-29 1990-01-16 University Of Florida Beta-agonist carbostyril derivatives, assay method and pharmacological composition
JPH026831U (ja) * 1988-06-28 1990-01-17
EP1565472A2 (en) * 2002-11-27 2005-08-24 Artesian Therapeutics, Inc. Compounds with mixed pde-inhibitory and beta-adrenergic antagonist or partial agonist activity for treatment of heart failure
FR2869893B1 (fr) * 2004-05-06 2006-07-28 Rhodia Chimie Sa Nouveaux granules de phosphates de calcium de type hydroxyapatite, leur procede de preparation et leurs applications
WO2005110990A1 (de) * 2004-05-13 2005-11-24 Boehringer Ingelheim International Gmbh Hydroxy-substituierte benzkondensierte heterozyklen als betaagonisten zur behandlung von atemwegserkrankungen
US7307076B2 (en) 2004-05-13 2007-12-11 Boehringer Ingelheim International Gmbh Beta agonists for the treatment of respiratory diseases
GB0624757D0 (en) * 2006-12-12 2007-01-17 Sosei R & D Ltd Novel compounds
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975391A (en) * 1973-12-26 1976-08-17 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
JPS539227B2 (ja) * 1973-12-26 1978-04-04
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
US4022776A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives
US3994901A (en) * 1974-06-13 1976-11-30 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653323B2 (en) 2001-11-13 2003-11-25 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US6670376B1 (en) 2001-11-13 2003-12-30 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US6949568B2 (en) 2001-11-13 2005-09-27 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US7125892B2 (en) 2001-11-13 2006-10-24 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US6747043B2 (en) 2002-05-28 2004-06-08 Theravance, Inc. Alkoxy aryl β2 adrenergic receptor agonists
US7582765B2 (en) 2003-05-08 2009-09-01 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
US7399863B2 (en) 2003-09-22 2008-07-15 Theravance, Inc. Amino-substituted ethylamino β2 adrenergic receptor agonists
US7964730B2 (en) 2003-09-22 2011-06-21 Theravance, Inc. Amino-substituted ethylamino β2 adrenergic receptor agonists
US7622467B2 (en) 2004-01-12 2009-11-24 Theravance, Inc. Aryl aniline derivatives as β2 adrenergic receptor agonists
US7994165B2 (en) 2004-01-12 2011-08-09 Theravance, Inc. Aryl aniline derivatives as β2 adrenergic receptor agonists
US7402673B2 (en) 2004-06-03 2008-07-22 Theravance, Inc. Diamine β2 adrenergic receptor agonists
US7566785B2 (en) 2004-09-10 2009-07-28 Theravance, Inc. Amidine substituted aryl aniline compounds

Also Published As

Publication number Publication date
SE7614539L (sv) 1978-04-09
AU2085576A (en) 1978-04-06
DE2658544C2 (de) 1985-10-03
SE434395B (sv) 1984-07-23
US4223137A (en) 1980-09-16
FR2378521B1 (ja) 1979-06-29
CH618431A5 (ja) 1980-07-31
NL174041B (nl) 1983-11-16
JPS609713B2 (ja) 1985-03-12
GB1540628A (en) 1979-02-14
NL174041C (nl) 1984-04-16
DE2658544A1 (de) 1978-04-13
CA1074801A (en) 1980-04-01
FR2378521A1 (fr) 1978-08-25
JPS5346983A (en) 1978-04-27
NL7614329A (nl) 1978-04-11

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: OTSUKA PHARMACEUTICAL CO. LTD

Effective date: 19901231