BE846569A - Nouveaux derives phenylacetiques utiles notamment comme hypolipemiants et leur procede de preparation - Google Patents
Nouveaux derives phenylacetiques utiles notamment comme hypolipemiants et leur procede de preparationInfo
- Publication number
- BE846569A BE846569A BE170922A BE170922A BE846569A BE 846569 A BE846569 A BE 846569A BE 170922 A BE170922 A BE 170922A BE 170922 A BE170922 A BE 170922A BE 846569 A BE846569 A BE 846569A
- Authority
- BE
- Belgium
- Prior art keywords
- hypolipemiants
- preparation process
- derivatives useful
- new phenylacetic
- new
- Prior art date
Links
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Quinoline Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61680675A | 1975-09-25 | 1975-09-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE846569A true BE846569A (fr) | 1977-03-24 |
Family
ID=24471018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE170922A BE846569A (fr) | 1975-09-25 | 1976-09-24 | Nouveaux derives phenylacetiques utiles notamment comme hypolipemiants et leur procede de preparation |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4125729A (xx) |
| JP (1) | JPS5239647A (xx) |
| AR (1) | AR212921A1 (xx) |
| AT (1) | AT348992B (xx) |
| AU (1) | AU1752576A (xx) |
| BE (1) | BE846569A (xx) |
| DD (1) | DD129056A5 (xx) |
| DE (1) | DE2642164A1 (xx) |
| DK (1) | DK431176A (xx) |
| ES (1) | ES451822A1 (xx) |
| FI (1) | FI762701A (xx) |
| FR (1) | FR2325368A1 (xx) |
| GB (1) | GB1554299A (xx) |
| HU (1) | HU173950B (xx) |
| LU (1) | LU75858A1 (xx) |
| NL (1) | NL7610480A (xx) |
| NO (1) | NO763273L (xx) |
| NZ (1) | NZ181868A (xx) |
| PT (1) | PT65601B (xx) |
| RO (1) | RO70552A (xx) |
| SE (1) | SE7610630L (xx) |
| ZA (1) | ZA765075B (xx) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0206772A3 (en) * | 1985-06-20 | 1988-05-11 | E.I. Du Pont De Nemours And Company | Herbicidal aryloxybenzeneacetic acid derivatives |
| US5284971A (en) * | 1992-07-16 | 1994-02-08 | Syntex (U.S.A.) Inc. | 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents |
| CN1082099C (zh) * | 1999-05-08 | 2002-04-03 | 吉林大学 | 纳米引晶法选择性生长金刚石膜的工艺 |
| WO2002009651A2 (en) * | 2000-08-02 | 2002-02-07 | Smithkline Beecham Corporation | Fatty acid synthase inhibitors |
| CA2437118A1 (en) * | 2001-02-09 | 2002-08-22 | Merck & Co., Inc. | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders |
| CN100562516C (zh) | 2001-12-27 | 2009-11-25 | 第一制药株式会社 | β-淀粉样蛋白产生和分泌的抑制剂 |
| PL379466A1 (pl) | 2003-06-30 | 2006-09-18 | Daiichi Sankyo Company , Limited | Heterocykliczne pochodne metylosulfonu |
| KR20070011312A (ko) * | 2004-02-18 | 2007-01-24 | 메타볼렉스, 인코포레이티드 | 항당뇨병제로서 알파-(트리플루오로메틸-치환된 아릴옥시,아릴아미노, 아릴티오 또는아릴메틸)-트리플루오로메틸-치환된 페닐아세트산 및 이의유도체 |
| CA2567437A1 (en) * | 2004-05-25 | 2005-12-08 | Metabolex, Inc. | Substituted triazoles as modulators of ppar and methods of their preparation |
| JP2008500358A (ja) * | 2004-05-25 | 2008-01-10 | メタボレックス インコーポレーティッド | Ｐｐａｒのモジュレーターとしての、二環式の置換されたトリアゾール、およびこれらの調製方法 |
| GB0510585D0 (en) * | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
| ES2909884T3 (es) * | 2013-08-20 | 2022-05-10 | Univ Washington Through Its Center For Commercialization | Inhibidores nuevos y específicos de la hidroxilasa del ácido retinoico del citocromo P450 26 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3517051A (en) * | 1964-03-20 | 1970-06-23 | Merck & Co Inc | Phenoxy substituted phenylacetic acids |
| US3378582A (en) * | 1964-03-20 | 1968-04-16 | Merck & Co Inc | (alpha-phenoxy)-and (alpha-phenylthio)-omegaphenyl-alkanoic acids |
| US3707549A (en) * | 1967-12-05 | 1972-12-26 | Lilly Co Eli | Alpha-substituted hydrocinnamic acids and derivatives thereof |
| US3600437A (en) * | 1969-05-28 | 1971-08-17 | Lilly Co Eli | Substituted phenylalkanoic acids and derivatives thereof |
-
1976
- 1976-08-24 ZA ZA765075A patent/ZA765075B/xx unknown
- 1976-08-26 NZ NZ181868A patent/NZ181868A/xx unknown
- 1976-09-01 GB GB36256/76A patent/GB1554299A/en not_active Expired
- 1976-09-03 AR AR264583A patent/AR212921A1/es active
- 1976-09-07 AU AU17525/76A patent/AU1752576A/en not_active Expired - Fee Related
- 1976-09-15 RO RO7687540A patent/RO70552A/ro unknown
- 1976-09-16 PT PT65601A patent/PT65601B/pt unknown
- 1976-09-20 DE DE19762642164 patent/DE2642164A1/de not_active Withdrawn
- 1976-09-21 NL NL7610480A patent/NL7610480A/xx not_active Application Discontinuation
- 1976-09-22 FI FI762701A patent/FI762701A/fi not_active Application Discontinuation
- 1976-09-22 HU HU76AE478A patent/HU173950B/hu unknown
- 1976-09-23 LU LU75858A patent/LU75858A1/xx unknown
- 1976-09-23 FR FR7628621A patent/FR2325368A1/fr not_active Withdrawn
- 1976-09-23 AT AT705376A patent/AT348992B/de not_active IP Right Cessation
- 1976-09-24 NO NO763273A patent/NO763273L/no unknown
- 1976-09-24 ES ES451822A patent/ES451822A1/es not_active Expired
- 1976-09-24 BE BE170922A patent/BE846569A/xx unknown
- 1976-09-24 DK DK431176A patent/DK431176A/da unknown
- 1976-09-24 DD DD7600194972A patent/DD129056A5/xx unknown
- 1976-09-24 SE SE7610630A patent/SE7610630L/xx unknown
- 1976-09-24 JP JP51113815A patent/JPS5239647A/ja active Pending
-
1977
- 1977-02-17 US US05/769,741 patent/US4125729A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE2642164A1 (de) | 1977-04-07 |
| PT65601A (en) | 1976-10-01 |
| LU75858A1 (xx) | 1977-05-04 |
| NZ181868A (en) | 1979-06-08 |
| HU173950B (hu) | 1979-09-28 |
| ZA765075B (en) | 1977-08-31 |
| FI762701A (xx) | 1977-03-26 |
| GB1554299A (en) | 1979-10-17 |
| RO70552A (ro) | 1981-09-24 |
| AR212921A1 (es) | 1978-11-15 |
| ES451822A1 (es) | 1977-12-16 |
| AT348992B (de) | 1979-03-12 |
| DK431176A (da) | 1977-03-26 |
| PT65601B (en) | 1978-03-28 |
| FR2325368A1 (fr) | 1977-04-22 |
| NO763273L (no) | 1977-03-28 |
| AU1752576A (en) | 1978-03-16 |
| SE7610630L (sv) | 1977-03-26 |
| US4125729A (en) | 1978-11-14 |
| JPS5239647A (en) | 1977-03-28 |
| NL7610480A (nl) | 1977-03-29 |
| DD129056A5 (de) | 1977-12-28 |
| ATA705376A (de) | 1978-08-15 |
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