BE839615A - Nouvelles amidinourees, leur preparation et leur emploi - Google Patents

Nouvelles amidinourees, leur preparation et leur emploi

Info

Publication number
BE839615A
BE839615A BE165207A BE165207A BE839615A BE 839615 A BE839615 A BE 839615A BE 165207 A BE165207 A BE 165207A BE 165207 A BE165207 A BE 165207A BE 839615 A BE839615 A BE 839615A
Authority
BE
Belgium
Prior art keywords
amidinouraes
preparation
new
new amidinouraes
Prior art date
Application number
BE165207A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE839615A publication Critical patent/BE839615A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/28—Y being a hetero atom, e.g. thiobiuret
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/34—Isothioureas having sulfur atoms of isothiourea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/12—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE165207A 1975-03-31 1976-03-16 Nouvelles amidinourees, leur preparation et leur emploi BE839615A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/558,186 US4025652A (en) 1975-03-31 1975-03-31 Amidinoureas

Publications (1)

Publication Number Publication Date
BE839615A true BE839615A (fr) 1976-07-16

Family

ID=24228538

Family Applications (1)

Application Number Title Priority Date Filing Date
BE165207A BE839615A (fr) 1975-03-31 1976-03-16 Nouvelles amidinourees, leur preparation et leur emploi

Country Status (14)

Country Link
US (2) US4025652A (fr)
AR (1) AR215584A1 (fr)
AU (1) AU503753B2 (fr)
BE (1) BE839615A (fr)
CA (1) CA1081710A (fr)
CH (1) CH620200A5 (fr)
DE (1) DE2546744A1 (fr)
ES (1) ES446548A1 (fr)
FR (1) FR2305975A2 (fr)
GB (1) GB1541059A (fr)
IL (1) IL48209A (fr)
MX (1) MX3432E (fr)
NL (1) NL7603176A (fr)
ZA (1) ZA761927B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4488993A (en) * 1972-09-22 1984-12-18 William H. Rorer, Inc. Amidinoureas
US4326074A (en) * 1972-09-22 1982-04-20 William H. Rorer, Inc. Amidinoureas
US4204000A (en) * 1975-03-31 1980-05-20 William H. Rorer, Inc. Anti-ulcer amidinoureas
US4203920A (en) * 1975-03-31 1980-05-20 William H. Rorer, Inc. Amidinoureas
US4242340A (en) * 1976-03-30 1980-12-30 William H. Rorer, Inc. Method for the treatment of diarrheal disease conditions and symptoms in mammals
US4218450A (en) * 1976-03-30 1980-08-19 William H. Rorer, Inc. Method for treatment of gastrointestinal spasmodic disease conditions or symptoms in mammals
US4209624A (en) * 1976-10-26 1980-06-24 Cooper Laboratories, Inc. Process for preparing substituted bis(amidinoureas)
US4353842A (en) * 1978-09-14 1982-10-12 William H. Rorer, Inc. Amidinoureas
US4418209A (en) * 1980-04-14 1983-11-29 William H. Rorer, Inc. Amidinothioureas
JPS58501468A (ja) * 1981-08-24 1983-09-01 ロウラ−　インタ−ナシヨナル　（オ−バ−シ−ズ）　インコ−ポレ−テツド 複素環アミジノ置換尿素およびそれらの薬剤利用
AU7583081A (en) * 1981-08-24 1983-03-08 Rorer International (Overseas) Inc. The treatment and prevention of scours in animals
US4562209A (en) * 1981-08-24 1985-12-31 William H. Rorer, Inc. Promotion of feed efficiency in animals
JPS6160673A (ja) * 1984-08-30 1986-03-28 Yamanouchi Pharmaceut Co Ltd グアニジノチアゾ−ル誘導体の製造法
DE4018070A1 (de) * 1990-06-06 1991-12-12 Bayer Ag Morpholinoharnstoff-derivate
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US5667773A (en) * 1996-03-12 1997-09-16 Adolor Corporation Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic conditions therewith
US5888494A (en) * 1996-03-12 1999-03-30 Adolor Corporation Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic and pruritic conditions therewith
US6353004B1 (en) 1997-07-14 2002-03-05 Adolor Coporation Peripherally acting anti-pruritic opiates
US5849762A (en) * 1997-07-14 1998-12-15 Adolor Corporation Peripherally acting anti-pruritic opiates
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
DK2368553T3 (en) 2003-04-08 2015-02-09 Progenics Pharm Inc Pharmaceutical preparation comprising methylnaltrexone
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) * 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
PL2137191T3 (pl) 2007-03-29 2016-12-30 Antagoniści obwodowego receptora opioidowego i ich zastosowania
EP2134718A2 (fr) 2007-03-29 2009-12-23 Progenics Pharmaceuticals, Inc. Formes cristallines, et leurs utilisations
AU2008349873B2 (en) 2008-02-06 2014-02-13 Progenics Pharmaceuticals, Inc. Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
CA2676881C (fr) 2008-09-30 2017-04-25 Wyeth Antagonistes de recepteurs opioides peripheriques, et leurs utilisations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2631152A (en) * 1952-01-24 1953-03-10 American Cyanamid Co Guanylurea salts of penicillin
US3320229A (en) * 1963-08-26 1967-05-16 Stauffer Chemical Co Complexes of guanidines with completely halogenated acetones
GB1194835A (en) * 1966-07-07 1970-06-10 Wellcome Found Novel 1-Amidino-3-Phenyl-Urea Derivatives, the preparation thereof and Compositions containing the same
US3759991A (en) * 1970-05-04 1973-09-18 Exxon Research Engineering Co Thiocarbamylated guanidines - growth regulant
PH12016A (en) * 1972-09-22 1978-10-06 Rorer Inc William H Amidinoureas

Also Published As

Publication number Publication date
ZA761927B (en) 1977-04-27
FR2305975B2 (fr) 1978-12-15
DE2546744A1 (de) 1977-02-17
FR2305975A2 (fr) 1976-10-29
CA1081710A (fr) 1980-07-15
CH620200A5 (fr) 1980-11-14
AR215584A1 (es) 1979-10-31
AU1230176A (en) 1977-09-29
NL7603176A (nl) 1976-10-04
GB1541059A (en) 1979-02-21
AU503753B2 (en) 1979-09-20
IL48209A (en) 1981-09-13
US4025652A (en) 1977-05-24
IL48209A0 (en) 1975-11-25
ES446548A1 (es) 1977-10-16
US4115564A (en) 1978-09-19
MX3432E (es) 1980-11-24

Similar Documents

Publication Publication Date Title
BE839615A (fr) Nouvelles amidinourees, leur preparation et leur emploi
BE833044A (fr) 4-arylpiperidines 1, 3, 4 -trisubtituees et leur preparation
BE847368A (fr) Nouvelles compositions pharmaceutiques et leur preparation,
BE843152A (fr) Nouvelles cephalosporimes, leur preparation et leur emploi
BE839255A (fr) Piperazinylimino rifamycines, leur preparation et leur utilisation
BE832921A (fr) Nouvelles rifamycines et leur preparation
BE833369A (fr) Nouvelles benzodiazepines et leur preparation
FR2309536A1 (fr) Nouvelles 1,3 diceto-1,2,3,4,4a,5,6,7-octahydroisoquinoleines, leur preparation et leur utilisation
FR2335567A1 (fr) Colorants disazoiques, leur obtention et leur application
BE829082A (fr) Nouvelles diamines, leur preparation et leur application
BE839256A (fr) Piperazinylimino rifamycines, leur preparation et leur utilisation
BE847165A (fr) Nouvelles compositions detergentes et leur preparation,
FR2283689A1 (fr) Nouvelles cephamycines, leur preparation et leur application
FR2297203A1 (fr) Mono-hydroxybutyrates du 1,3-butanediol et leur preparation
BE861694A (fr) 3-carboxy-4-oxo-1,4-dihydro-1,8-naphtyridines et leur preparation
BE844029A (fr) Diepoxy-androstanes et leur preparation
BE846502A (fr) Agents antimicrobiens et leur preparation
BE826925A (fr) Nouvelles pyrrolodiazepines et leur preparation
BE825366A (fr) Nouveaux polycarbonates, leur preparation et leur emploi
BE820256A (fr) Nouvelles phenoxyalkylamines et leur preparation
BE843237A (fr) 1-acyl-1,2,3,4-tetrahydro-6-quinoleinols et leur preparation
FR2313358A1 (fr) Urethanne-polythiols et leur preparation
BE843395A (fr) Sulfonamido-salicylaldehydes, leur obtention et leur application
FR2316292A1 (fr) Colorants disazoiques, leur obtention et leur application
BE832464A (fr) 3,4-dihydro-2h-isoquinoleine-1-thiones et leur preparation