BE838708A - Nouveaux derives 6,7-benzomorphaniques possedant des proprietes analgesiques - Google Patents
Nouveaux derives 6,7-benzomorphaniques possedant des proprietes analgesiquesInfo
- Publication number
- BE838708A BE838708A BE164433A BE164433A BE838708A BE 838708 A BE838708 A BE 838708A BE 164433 A BE164433 A BE 164433A BE 164433 A BE164433 A BE 164433A BE 838708 A BE838708 A BE 838708A
- Authority
- BE
- Belgium
- Prior art keywords
- benzomorphanic
- derivatives
- new
- analgesic properties
- analgesic
- Prior art date
Links
- 230000000202 analgesic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- One-Way And Automatic Clutches, And Combinations Of Different Clutches (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7891/75A GB1513961A (en) | 1975-02-25 | 1975-02-25 | 6,7-benzomorphans method for their preparation and intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE838708A true BE838708A (fr) | 1976-08-19 |
Family
ID=9841801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE164433A BE838708A (fr) | 1975-02-25 | 1976-02-19 | Nouveaux derives 6,7-benzomorphaniques possedant des proprietes analgesiques |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US4128548A (en:Method) |
| JP (2) | JPS51111550A (en:Method) |
| AT (1) | AT360663B (en:Method) |
| AU (1) | AU505939B2 (en:Method) |
| BE (1) | BE838708A (en:Method) |
| CA (1) | CA1080704A (en:Method) |
| CH (2) | CH621115A5 (en:Method) |
| DE (1) | DE2606267A1 (en:Method) |
| DK (1) | DK76176A (en:Method) |
| ES (1) | ES445494A1 (en:Method) |
| FR (1) | FR2302092A1 (en:Method) |
| GB (1) | GB1513961A (en:Method) |
| HU (1) | HU173571B (en:Method) |
| IE (1) | IE43450B1 (en:Method) |
| IL (1) | IL48990A (en:Method) |
| IT (1) | IT1057250B (en:Method) |
| LU (1) | LU74431A1 (en:Method) |
| NL (1) | NL7601924A (en:Method) |
| PH (1) | PH12974A (en:Method) |
| SE (1) | SE7602235L (en:Method) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5381778A (en) * | 1976-12-27 | 1978-07-19 | Toshiharu Nakao | Cloth loop forming apparatus in steaming apparatus |
| NL7804509A (nl) * | 1978-04-26 | 1979-10-30 | Acf Chemiefarma Nv | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan. |
| DE2828039A1 (de) * | 1978-06-26 | 1980-01-10 | Boehringer Sohn Ingelheim | 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung |
| US4208523A (en) * | 1978-11-30 | 1980-06-17 | Sterling Drug Inc. | 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines |
| NL7907800A (nl) * | 1979-10-23 | 1981-04-27 | Acf Chemiefarma Nv | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten. |
| US5490436A (en) * | 1994-03-17 | 1996-02-13 | At&T Corp. | Liquid-chamber apparatus for active, dynamic balancing of rotating machinery |
| EP1506174B1 (en) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Use of naltrexone for treating kidney and liver damage |
| US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) * | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| CA2697168A1 (en) * | 2007-07-26 | 2009-02-05 | Vitae Pharmaceuticals, Inc. | Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
| AR069207A1 (es) * | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| TW200927115A (en) * | 2007-11-16 | 2009-07-01 | Boehringer Ingelheim Int | Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| EP2229368A1 (en) | 2007-12-11 | 2010-09-22 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) * | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| ATE531696T1 (de) * | 2008-02-12 | 2011-11-15 | Boehringer Ingelheim Int | Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung |
| CN102089300B (zh) | 2008-05-01 | 2014-06-18 | 生命医药公司 | 11β-羟基类固醇脱氢酶1的环状抑制剂 |
| US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| EP2324017B1 (en) | 2008-07-25 | 2014-12-31 | Boehringer Ingelheim International GmbH | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
| DK2324018T3 (da) | 2008-07-25 | 2013-10-14 | Boehringer Ingelheim Int | Cykliske inhibitorer af 11 beta-hydroxysteroid dehydrogenase 1 |
| US8680093B2 (en) | 2009-04-30 | 2014-03-25 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2010139673A1 (en) | 2009-06-02 | 2010-12-09 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5656986B2 (ja) | 2009-06-11 | 2015-01-21 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １，３−オキサジナン−２−オン構造に基づく１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 |
| JP5456555B2 (ja) | 2010-04-23 | 2014-04-02 | 株式会社マキタ | 電動工具 |
| EP2582698B1 (en) | 2010-06-16 | 2016-09-14 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| WO2011161128A1 (en) | 2010-06-25 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders |
| EP2635268A1 (en) | 2010-11-02 | 2013-09-11 | Boehringer Ingelheim International GmbH | Pharmaceutical combinations for the treatment of metabolic disorders |
| JP2014524438A (ja) | 2011-08-17 | 2014-09-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インデノピリジン誘導体 |
| JP2022128135A (ja) * | 2021-02-22 | 2022-09-01 | 株式会社マキタ | 電動工具 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3138603A (en) * | 1958-10-31 | 1964-06-23 | Everette L May | New benzomorphans (methanobenzazocines) and preparation thereof |
| US3372165A (en) * | 1960-12-01 | 1968-03-05 | Sterling Drug Inc | 1, 2, 3, 4, 5, 6-hexahydro-8-hydroxy-2, 6-methano-3-benzazocine derivatives |
| IE34235B1 (en) * | 1969-06-04 | 1975-03-19 | Acf Chemiefarma Nv | 6,7-benzomorphans and their preparation |
| NL156047B (nl) * | 1969-06-04 | 1978-03-15 | Acf Chemiefarma Nv | Werkwijze voor de bereiding van farmaceutische preparaten met analgetische en/of morfine-antagonistische werking, gevormde preparaten, alsmede werkwijze voor de bereiding van daartoe geschikte nieuwe 6,7-benzomorfanen. |
| CA1010031A (en) * | 1972-10-31 | 1977-05-10 | Kentaro Tamaki | 6,7-benzomorphan derivatives |
| US4010164A (en) * | 1973-03-28 | 1977-03-01 | Boehringer Ingelheim Gmbh | N-(furyl-methyl)-2-hydroxy-5,9,9-trimethyl-benzomorphans and salts thereof |
| SU510999A3 (ru) * | 1973-10-27 | 1976-04-15 | К.Х.Берингер Зон, (Фирма) | Способ получени (метоксиметил-фурилметил)6,7-бензоморфанов илиморфинанов |
| US4087532A (en) * | 1974-03-09 | 1978-05-02 | Boehringer Ingelheim Gmbh | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof |
| US4032529A (en) * | 1974-09-20 | 1977-06-28 | Sterling Drug Inc. | Aminomethanobenzazocine intermediates |
-
1975
- 1975-02-25 GB GB7891/75A patent/GB1513961A/en not_active Expired
-
1976
- 1976-02-05 AU AU10856/76A patent/AU505939B2/en not_active Expired
- 1976-02-09 IL IL48990A patent/IL48990A/xx unknown
- 1976-02-17 DE DE19762606267 patent/DE2606267A1/de not_active Withdrawn
- 1976-02-17 US US05/658,739 patent/US4128548A/en not_active Expired - Lifetime
- 1976-02-19 BE BE164433A patent/BE838708A/xx unknown
- 1976-02-20 IE IE334/76A patent/IE43450B1/en unknown
- 1976-02-23 JP JP1875676A patent/JPS51111550A/ja active Pending
- 1976-02-23 PH PH18131A patent/PH12974A/en unknown
- 1976-02-24 FR FR7605083A patent/FR2302092A1/fr active Granted
- 1976-02-24 SE SE7602235A patent/SE7602235L/xx not_active Application Discontinuation
- 1976-02-24 IT IT67415/76A patent/IT1057250B/it active
- 1976-02-24 ES ES445494A patent/ES445494A1/es not_active Expired
- 1976-02-24 DK DK76176*#A patent/DK76176A/da unknown
- 1976-02-25 CA CA246,540A patent/CA1080704A/en not_active Expired
- 1976-02-25 AT AT137276A patent/AT360663B/de not_active IP Right Cessation
- 1976-02-25 LU LU74431A patent/LU74431A1/xx unknown
- 1976-02-25 HU HU76CE1075A patent/HU173571B/hu unknown
- 1976-02-25 CH CH234376A patent/CH621115A5/de not_active IP Right Cessation
- 1976-02-25 NL NL7601924A patent/NL7601924A/xx not_active Application Discontinuation
- 1976-02-25 JP JP51019022A patent/JPS51118767A/ja active Pending
-
1978
- 1978-07-28 US US05/928,862 patent/US4268673A/en not_active Expired - Lifetime
-
1979
- 1979-11-20 CH CH1036579A patent/CH623572A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1513961A (en) | 1978-06-14 |
| JPS51111550A (en) | 1976-10-01 |
| SE7602235L (sv) | 1976-08-26 |
| FR2302092B1 (en:Method) | 1978-11-10 |
| IT1057250B (it) | 1982-03-10 |
| HU173571B (hu) | 1979-06-28 |
| ES445494A1 (es) | 1977-11-01 |
| IE43450B1 (en) | 1981-02-25 |
| AT360663B (de) | 1981-01-26 |
| IE43450L (en) | 1976-08-25 |
| CA1080704A (en) | 1980-07-01 |
| US4268673A (en) | 1981-05-19 |
| NL7601924A (nl) | 1976-08-27 |
| AU1085676A (en) | 1977-08-11 |
| LU74431A1 (en:Method) | 1976-08-13 |
| CH623572A5 (en:Method) | 1981-06-15 |
| ATA137276A (de) | 1980-06-15 |
| AU505939B2 (en) | 1979-12-06 |
| CH621115A5 (en:Method) | 1981-01-15 |
| JPS51118767A (en) | 1976-10-18 |
| DE2606267A1 (de) | 1976-09-30 |
| IL48990A0 (en) | 1976-04-30 |
| PH12974A (en) | 1979-10-24 |
| US4128548A (en) | 1978-12-05 |
| DK76176A (da) | 1976-08-26 |
| IL48990A (en) | 1980-01-31 |
| FR2302092A1 (fr) | 1976-09-24 |
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