BE832332A - Nouveaux derives de l'acide 3-quinoleine carboxylique, procede de preparation et compositions pharmaceutiques - Google Patents
Nouveaux derives de l'acide 3-quinoleine carboxylique, procede de preparation et compositions pharmaceutiquesInfo
- Publication number
- BE832332A BE832332A BE159113A BE159113A BE832332A BE 832332 A BE832332 A BE 832332A BE 159113 A BE159113 A BE 159113A BE 159113 A BE159113 A BE 159113A BE 832332 A BE832332 A BE 832332A
- Authority
- BE
- Belgium
- Prior art keywords
- quinoleine
- preparation
- carboxylic acid
- pharmaceutical compositions
- new derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7428038A FR2281761A1 (fr) | 1974-08-13 | 1974-08-13 | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE832332A true BE832332A (fr) | 1976-02-12 |
Family
ID=9142372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE159113A BE832332A (fr) | 1974-08-13 | 1975-08-12 | Nouveaux derives de l'acide 3-quinoleine carboxylique, procede de preparation et compositions pharmaceutiques |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US3992540A (ru) |
| JP (1) | JPS5925793B2 (ru) |
| AR (1) | AR208323A1 (ru) |
| AT (1) | AT340928B (ru) |
| BE (1) | BE832332A (ru) |
| CA (1) | CA1055499A (ru) |
| CH (1) | CH614953A5 (ru) |
| DD (1) | DD122972A5 (ru) |
| DE (1) | DE2536206C2 (ru) |
| DK (1) | DK142319B (ru) |
| ES (1) | ES440079A1 (ru) |
| FR (1) | FR2281761A1 (ru) |
| GB (1) | GB1484787A (ru) |
| HU (1) | HU170060B (ru) |
| IE (1) | IE41841B1 (ru) |
| IL (1) | IL47820A (ru) |
| LU (1) | LU73193A1 (ru) |
| NL (1) | NL7509625A (ru) |
| SE (1) | SE425244B (ru) |
| SU (1) | SU566522A3 (ru) |
| ZA (1) | ZA754905B (ru) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2340735A1 (fr) * | 1976-02-11 | 1977-09-09 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| FR2443467A1 (fr) * | 1978-12-08 | 1980-07-04 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| FR2482596A1 (fr) * | 1980-05-19 | 1981-11-20 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament |
| IE52670B1 (en) * | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
| HU190796B (en) * | 1981-06-12 | 1986-11-28 | Roussel Uclaf,Fr | Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives |
| FR2507602A1 (fr) * | 1981-06-12 | 1982-12-17 | Roussel Uclaf | Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| FR2523130A1 (fr) * | 1982-03-15 | 1983-09-16 | Roussel Uclaf | Nouveaux derives de la n-dihydrothiazolyl-3-quinoleine carboxamide, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| FR2509728A1 (fr) * | 1981-07-17 | 1983-01-21 | Roussel Uclaf | Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| FR2537140B1 (fr) * | 1982-12-07 | 1986-07-18 | Roussel Uclaf | Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant |
| FR2566405B1 (fr) * | 1984-06-25 | 1986-09-26 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus |
| US4602014A (en) * | 1984-07-09 | 1986-07-22 | Ciba-Geigy Corporation | Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators |
| US4689182A (en) * | 1985-12-20 | 1987-08-25 | Warner-Lambert Company | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity |
| US4990533A (en) * | 1985-12-20 | 1991-02-05 | Warner-Lambert Co. | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| DK1773816T3 (en) | 2004-06-24 | 2015-01-26 | Vertex Pharma | Modulators of ATP-binding cassette transporters |
| US20090105272A1 (en) * | 2005-12-24 | 2009-04-23 | Grootenhuis Peter D J | Prodrugs of modulators of ABC transporters |
| JP5409010B2 (ja) | 2005-12-28 | 2014-02-05 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ｎ−［２，４−ビス（１，１−ジメチルエチル）−５−ヒドロキシフェニル］−１，４−ジヒドロ−４−オキソキノリン−３−カルボキサミドの固体形態 |
| NZ624460A (en) | 2009-03-20 | 2015-12-24 | Vertex Pharma | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| CN104470518A (zh) | 2012-02-27 | 2015-03-25 | 沃泰克斯药物股份有限公司 | 药物组合物及其施用 |
| CA2963945C (en) | 2014-10-07 | 2023-01-10 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH71A (de) * | 1888-11-15 | 1889-06-13 | Th Hunziker | Apparat zum Absticken verlängerter Nädlinge für Handstickmaschinen |
| US2798070A (en) * | 1954-02-04 | 1957-07-02 | Mcneilab Inc | Quaternary quinoline carboxamide salts and method of preparing same |
| JPS4323948Y1 (ru) * | 1965-03-06 | 1968-10-09 | ||
| US3524858A (en) * | 1967-05-18 | 1970-08-18 | Warner Lambert Pharmaceutical | 1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid |
| US3496184A (en) * | 1969-03-18 | 1970-02-17 | Ciba Geigy Corp | Cyclopropylmethoxy-3-quinoline carboxylic acids and esters |
-
1974
- 1974-08-13 FR FR7428038A patent/FR2281761A1/fr active Granted
-
1975
- 1975-01-01 AR AR259945A patent/AR208323A1/es active
- 1975-07-22 SE SE7508332A patent/SE425244B/xx not_active IP Right Cessation
- 1975-07-25 IL IL47820A patent/IL47820A/xx unknown
- 1975-07-28 US US05/599,369 patent/US3992540A/en not_active Expired - Lifetime
- 1975-07-30 ZA ZA00754905A patent/ZA754905B/xx unknown
- 1975-08-01 SU SU7502159095A patent/SU566522A3/ru active
- 1975-08-06 DD DD187721A patent/DD122972A5/xx unknown
- 1975-08-07 ES ES440079A patent/ES440079A1/es not_active Expired
- 1975-08-07 JP JP50095466A patent/JPS5925793B2/ja not_active Expired
- 1975-08-11 CA CA233,230A patent/CA1055499A/en not_active Expired
- 1975-08-12 CH CH1048375A patent/CH614953A5/xx not_active IP Right Cessation
- 1975-08-12 BE BE159113A patent/BE832332A/xx not_active IP Right Cessation
- 1975-08-12 IE IE1796/75A patent/IE41841B1/en unknown
- 1975-08-12 LU LU73193A patent/LU73193A1/xx unknown
- 1975-08-12 GB GB33609/75A patent/GB1484787A/en not_active Expired
- 1975-08-13 NL NL7509625A patent/NL7509625A/xx not_active Application Discontinuation
- 1975-08-13 DK DK366175AA patent/DK142319B/da not_active IP Right Cessation
- 1975-08-13 AT AT630875A patent/AT340928B/de not_active IP Right Cessation
- 1975-08-13 DE DE2536206A patent/DE2536206C2/de not_active Expired
- 1975-08-13 HU HURO850A patent/HU170060B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK142319C (ru) | 1981-03-02 |
| FR2281761B1 (ru) | 1978-07-28 |
| GB1484787A (en) | 1977-09-08 |
| AU8340875A (en) | 1977-01-27 |
| IL47820A (en) | 1978-10-31 |
| DE2536206A1 (de) | 1976-03-04 |
| JPS5925793B2 (ja) | 1984-06-21 |
| LU73193A1 (ru) | 1976-08-13 |
| NL7509625A (nl) | 1976-02-17 |
| IE41841B1 (en) | 1980-04-09 |
| ZA754905B (en) | 1976-08-25 |
| JPS5141366A (en) | 1976-04-07 |
| DK142319B (da) | 1980-10-13 |
| AT340928B (de) | 1978-01-10 |
| AR208323A1 (es) | 1976-12-20 |
| ATA630875A (de) | 1977-05-15 |
| CH614953A5 (ru) | 1979-12-28 |
| CA1055499A (en) | 1979-05-29 |
| IL47820A0 (en) | 1975-10-15 |
| DK366175A (ru) | 1976-02-14 |
| ES440079A1 (es) | 1977-02-16 |
| DE2536206C2 (de) | 1984-07-19 |
| SE7508332L (sv) | 1976-02-16 |
| SE425244B (sv) | 1982-09-13 |
| HU170060B (ru) | 1977-03-28 |
| SU566522A3 (ru) | 1977-07-25 |
| IE41841L (en) | 1976-02-13 |
| DD122972A5 (de) | 1976-11-12 |
| US3992540A (en) | 1976-11-16 |
| FR2281761A1 (fr) | 1976-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: ROUSSEL-UCLAF Effective date: 19900831 |