BE829611A - Chromanes a effet hypotenseur - Google Patents

Chromanes a effet hypotenseur

Info

Publication number
BE829611A
BE829611A BE156814A BE156814A BE829611A BE 829611 A BE829611 A BE 829611A BE 156814 A BE156814 A BE 156814A BE 156814 A BE156814 A BE 156814A BE 829611 A BE829611 A BE 829611A
Authority
BE
Belgium
Prior art keywords
hypotensory
chromanes
hypotensory chromanes
Prior art date
Application number
BE156814A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE829611A publication Critical patent/BE829611A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE156814A 1974-05-31 1975-05-28 Chromanes a effet hypotenseur BE829611A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24348/74A GB1495526A (en) 1974-05-31 1974-05-31 Chroman derivatives

Publications (1)

Publication Number Publication Date
BE829611A true BE829611A (fr) 1975-11-28

Family

ID=10210307

Family Applications (1)

Application Number Title Priority Date Filing Date
BE156814A BE829611A (fr) 1974-05-31 1975-05-28 Chromanes a effet hypotenseur

Country Status (15)

Country Link
US (1) US4048317A (th)
JP (2) JPS6044308B2 (th)
BE (1) BE829611A (th)
CA (1) CA1072090A (th)
DE (1) DE2523281A1 (th)
DK (1) DK244875A (th)
ES (1) ES438072A1 (th)
FR (1) FR2272659B1 (th)
GB (1) GB1495526A (th)
HK (1) HK20781A (th)
IE (1) IE41539B1 (th)
KE (1) KE3124A (th)
MY (1) MY8100356A (th)
NL (1) NL7506421A (th)
ZA (1) ZA753076B (th)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062870A (en) * 1974-05-31 1977-12-13 Beecham Group Limited Chroman derivatives
US4542150A (en) * 1975-09-17 1985-09-17 Cornell Research Foundation, Inc. Anti-juvenile hormones
US4391815A (en) * 1976-04-02 1983-07-05 Beecham Group Limited Cyanobenzano[b]pyrans
GB1511187A (en) * 1976-04-02 1978-05-17 Beecham Group Ltd Chromans
NZ183551A (en) * 1976-04-02 1978-09-20 Beecham Group Ltd Aminochromanols and pharmaceutical compositions containingthem
US4203895A (en) * 1978-04-14 1980-05-20 Warner-Lambert Company Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
EP0009912B1 (en) * 1978-10-04 1983-06-22 Beecham Group Plc Chromanol derivatives, a process for their preparation and pharmaceutical compositions comprising them
DE3064286D1 (en) * 1979-09-28 1983-08-25 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
EP0028449B1 (en) * 1979-09-28 1983-07-20 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
GB2064514B (en) * 1979-10-29 1984-01-18 Maruko Pharmaceutical Co Flavan compounds and acid addition salts thereof and pharmaceutical compositions thereof
EP0033613A1 (en) * 1980-02-02 1981-08-12 Beecham Group Plc Chromanol derivatives, a process for their preparation and compositions containing them
DE3163018D1 (en) 1980-02-02 1984-05-17 Beecham Group Plc Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them
DE3170604D1 (en) * 1980-08-21 1985-06-27 Beecham Group Plc Chromanol derivatives, their production and pharmaceutical compositions containing them
DE3274350D1 (en) * 1981-09-25 1987-01-08 Beecham Group Plc Pharmaceutically active benzopyran compounds
ZM7682A1 (en) * 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
EP0091748B1 (en) * 1982-04-08 1986-06-18 Beecham Group Plc Antihypertensive benzopyranols
DE3368057D1 (en) * 1982-05-21 1987-01-15 Beecham Group Plc Pharmaceutically active aminobenzopyrans
JPS59110690A (ja) * 1982-12-16 1984-06-26 Dai Ichi Seiyaku Co Ltd ベンゾピラン誘導体
EP0126311B1 (en) * 1983-05-18 1989-09-13 Beecham Group Plc Benzopyran derivatives.
CA1308108C (en) * 1987-10-27 1992-09-29 Dominick A. Quagliato Antihypertensive benzopyran derivatives
FR2637896B1 (fr) * 1988-10-17 1990-11-30 Adir Nouveaux derives de l'amino chromanol, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
GB8902118D0 (en) * 1989-02-01 1989-03-22 Beecham Group Plc Chemical process
US5239090A (en) * 1989-02-01 1993-08-24 Beecham Group P.L.C. Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates
GB8924373D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
HU222726B1 (hu) * 1990-02-06 2003-09-29 Pfizer, Inc., Piperidinszármazékok, eljárás elżállításukra és az ezeket tartalmazó gyógyszerkészítmények
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
ATE183184T1 (de) * 1994-01-31 1999-08-15 Pfizer Neuroprotektive chroman verbindungen
WO1997023209A1 (fr) * 1995-12-25 1997-07-03 Nissan Chemical Industries, Ltd. Agent therapeutique contre l'insuffisance cardiaque
AU713573B2 (en) 1996-07-26 1999-12-02 Nissan Chemical Industries Ltd. Chroman derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518273A (en) * 1966-08-03 1970-06-30 Warner Lambert Pharmaceutical Benzopyranquinolinol derivatives and process for their production
US3704323A (en) * 1969-12-23 1972-11-28 Squibb & Sons Inc Indane derivatives
US3743659A (en) * 1971-08-25 1973-07-03 Riker Laboratories Inc Substituted isochromans and processes therefor

Also Published As

Publication number Publication date
JPS6160077B2 (th) 1986-12-19
ES438072A1 (es) 1977-01-16
IE41539B1 (en) 1980-01-30
HK20781A (en) 1981-05-22
JPS6044308B2 (ja) 1985-10-02
US4048317A (en) 1977-09-13
KE3124A (en) 1981-05-15
ZA753076B (en) 1976-05-26
GB1495526A (en) 1977-12-21
FR2272659B1 (th) 1980-02-08
DK244875A (da) 1975-12-01
FR2272659A1 (th) 1975-12-26
JPS60231681A (ja) 1985-11-18
NL7506421A (nl) 1975-12-02
MY8100356A (en) 1981-12-31
AU8169375A (en) 1976-12-02
CA1072090A (en) 1980-02-19
DE2523281A1 (de) 1975-12-11
IE41539L (en) 1975-11-30
JPS511477A (th) 1976-01-08

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BEECHAM GROUP LTD

Effective date: 19880531