BE814032A - Nouveaux produits de reaction d'imidazoles substitues et de composes heterocycliques azotes - Google Patents

Nouveaux produits de reaction d'imidazoles substitues et de composes heterocycliques azotes

Info

Publication number
BE814032A
BE814032A BE143479A BE143479A BE814032A BE 814032 A BE814032 A BE 814032A BE 143479 A BE143479 A BE 143479A BE 143479 A BE143479 A BE 143479A BE 814032 A BE814032 A BE 814032A
Authority
BE
Belgium
Prior art keywords
imidazoles
substitutes
reaction products
heterocyclic compounds
new reaction
Prior art date
Application number
BE143479A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE814032A publication Critical patent/BE814032A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
BE143479A 1973-05-03 1974-04-22 Nouveaux produits de reaction d'imidazoles substitues et de composes heterocycliques azotes BE814032A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2106373A GB1419994A (en) 1973-05-03 1973-05-03 Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
GB3555173 1973-07-26

Publications (1)

Publication Number Publication Date
BE814032A true BE814032A (fr) 1974-10-22

Family

ID=26255089

Family Applications (1)

Application Number Title Priority Date Filing Date
BE143479A BE814032A (fr) 1973-05-03 1974-04-22 Nouveaux produits de reaction d'imidazoles substitues et de composes heterocycliques azotes

Country Status (18)

Country Link
US (1) US3932644A (xx)
JP (1) JPS5855145B2 (xx)
AU (1) AU477220B2 (xx)
BE (1) BE814032A (xx)
CA (1) CA1041108A (xx)
CH (1) CH605917A5 (xx)
DE (1) DE2421548A1 (xx)
ES (1) ES425936A1 (xx)
FI (1) FI62301C (xx)
FR (1) FR2227869B1 (xx)
GB (1) GB1419994A (xx)
HU (1) HU168863B (xx)
IE (1) IE40014B1 (xx)
IL (1) IL44526A (xx)
IN (1) IN138721B (xx)
NL (1) NL7404811A (xx)
SE (1) SE416299B (xx)
SU (1) SU719500A3 (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145546A (en) 1975-10-02 1979-03-20 Smith Kline & French Laboratories Limited 4-Pyrimidone compounds
US4185103A (en) 1977-03-19 1980-01-22 Smith Kline & French Laboratories Limited Pharmacologically active triazinones
US4218452A (en) 1975-10-02 1980-08-19 Smith Kline & French Laboratories Limited Substituted 4-pyrimidone compounds, compositions and methods of use

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578459A (en) * 1973-05-03 1986-03-25 Smithkline & French Laboratories Limited Heterocyclic alkylaminoheterocycles
JPS5239976U (xx) * 1975-09-12 1977-03-22
IN146736B (xx) * 1975-10-02 1979-08-25 Smith Kline French Lab
US4216318A (en) * 1975-12-29 1980-08-05 Smith Kline & French Laboratories Limited Heterocyclic alkyl 4-pyrimidones
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
US4649138A (en) * 1976-05-14 1987-03-10 Smithkline & French Laboratories Limited Pharmaceutical compositions
US4378365A (en) * 1976-05-14 1983-03-29 Smith Kline & French Laboratories Limited Pharmaceutical compositions
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
IE47044B1 (en) 1977-04-20 1983-12-14 Ici Ltd Guanidine derivatives
IN151188B (xx) * 1978-02-13 1983-03-05 Smith Kline French Lab
US4539207A (en) * 1978-02-13 1985-09-03 Smith Kline & French Laboratories Limited Pyrimidine compounds
IL57005A (en) * 1978-04-11 1983-11-30 Smith Kline French Lab Process for the preparation of 2-amino pyrimid-4-one derivatives and novel 2-nitroaminopyrimid-4-ones as intermediates therefor
AR228941A1 (es) 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
ATE1353T1 (de) 1978-05-24 1982-08-15 Imperial Chemical Industries Plc Anti-sekretion thiadiazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
US4584384A (en) * 1978-05-30 1986-04-22 Smith Kline & French Laboratories Limited Nitro pyrroles
ZA792608B (en) * 1978-05-30 1980-06-25 Smith Kline French Lab Nitro compounds
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them
ZA792607B (en) * 1978-05-30 1980-07-30 Smith Kline French Lab Nitro compounds
ZA793392B (en) * 1978-07-15 1980-08-27 Smith Kline French Lab Isoureas and isothioureas
ZA793443B (en) * 1978-07-26 1980-12-31 Glaxo Group Ltd Heterocyclic derivatives
US4374836A (en) 1978-10-16 1983-02-22 Imperial Chemical Industries Ltd. Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them
US4496567A (en) * 1978-11-13 1985-01-29 Smith Kline & French Laboratories Limited Phenyl alkylaminopyrimidones
US4521418A (en) * 1979-02-21 1985-06-04 Smith Kline & French Laboratories Limited Guanidinothiazolyl derivatives
US4256743A (en) * 1979-02-22 1981-03-17 President And Fellows Of Harvard College Inhibition of bone resorption with H1 -blocking antihistamines
JPS55120571A (en) * 1979-03-02 1980-09-17 Glaxo Group Ltd Heterocyclic derivative
PH18379A (en) * 1979-03-02 1985-06-19 Glaxo Group Ltd Triazole acylamines and pharmaceutical compositions thereof
AU531142B2 (en) * 1979-04-04 1983-08-11 Smith Kline & French Laboratories Limited 2 amino- pyimindones
DE3067564D1 (en) * 1979-10-22 1984-05-24 Glaxo Group Ltd 1,2,4-triazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
IL61233A (en) * 1979-10-24 1984-08-31 Smith Kline French Lab Guanidino thiazolylalkylamino(alkylthioalkylamino)nitro pyrroles,process for their preparation and pharmaceutical compositions containing them
IL61234A (en) * 1979-10-24 1984-03-30 Smith Kline French Lab Guanidino thiazolyl alkylamino(alkylthioalkylamino)nitrotetrahydropyridines,process for preparing them and pharmaceutical compositions containing them
FR2477150A1 (fr) * 1980-02-28 1981-09-04 Glaxo Group Ltd Nouveaux derives heterocycliques, procedes pour leur preparation et compositions pharmaceutiques les comportant
US4439609A (en) * 1980-10-01 1984-03-27 Smith Kline & French Laboratories Limited Pyridines
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
US4352933A (en) * 1981-02-06 1982-10-05 Smithkline Beckman Corporation Chemical methods and intermediates for preparing substituted pyrimidinones
US4439437A (en) * 1981-04-28 1984-03-27 Smith Kline & French Laboratories Limited 2-[2-Thiazolyl or 2-guanidino-4-thiazolyl methylthioethyl(or butyl)amino]-3-(hydroxy or carboxy)pyridines, compositions containing same and method of use
IE53068B1 (en) * 1981-06-15 1988-05-25 Merck & Co Inc Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
US4525477A (en) * 1981-12-02 1985-06-25 Smith Kline & French Laboratories Limited 2-Thiazolyl, isothiazolyl, oxazolyl and isoxazolyl alkylamino-3-nitro-heterocyclic compounds
EP0102026A3 (en) * 1982-08-20 1984-05-16 Hoechst Uk Limited Thiazole derivatives
EP0104611A3 (en) * 1982-09-28 1985-06-12 Hoechst Uk Limited Thiatriazine derivatives
JO1275B1 (en) * 1982-12-03 1985-04-20 هنري براون ثوماس Chemical process
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
JO1279B1 (en) * 1982-12-23 1985-04-20 جون ايف روبرت Pyridine derivatives
EP0113572B1 (en) * 1982-12-23 1988-02-03 Smith Kline & French Laboratories Limited Pyridine derivatives
GB8311443D0 (en) * 1983-04-27 1983-06-02 Smith Kline French Lab Chemical compounds
GB8318638D0 (en) * 1983-07-09 1983-08-10 Smith Kline French Lab Chemical compounds
GB8328907D0 (en) * 1983-10-28 1983-11-30 Smith Kline French Lab Chemical compounds
GB8332091D0 (en) * 1983-12-01 1984-01-11 Smith Kline French Lab Chemical compounds
GB9715814D0 (en) * 1997-07-25 1997-10-01 Black James Foundation Histamine H3 receptor ligands
GB2344588B (en) * 1997-07-25 2001-11-14 Black James Foundation 1H-4(5)-substituted imidazole derivatives their preparation and their use as histamine H 3 receptor ligands
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758759A (fr) * 1969-11-12 1971-05-10 Merck & Co Inc Pyridones anti-inflammatoires
US3853897A (en) * 1971-07-16 1974-12-10 Merck & Co Inc Certain 1-substituted-3-amino-1(2h)pyridones

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145546A (en) 1975-10-02 1979-03-20 Smith Kline & French Laboratories Limited 4-Pyrimidone compounds
US4159329A (en) 1975-10-02 1979-06-26 Smithkline & French Laboratories Limited 4-Pyrimidones compositions, and methods of use
US4218452A (en) 1975-10-02 1980-08-19 Smith Kline & French Laboratories Limited Substituted 4-pyrimidone compounds, compositions and methods of use
US4185103A (en) 1977-03-19 1980-01-22 Smith Kline & French Laboratories Limited Pharmacologically active triazinones

Also Published As

Publication number Publication date
US3932644A (en) 1976-01-13
JPS5855145B2 (ja) 1983-12-08
JPS5025565A (xx) 1975-03-18
FI62301B (fi) 1982-08-31
AU6859874A (en) 1975-11-06
CH605917A5 (xx) 1978-10-13
SU719500A3 (ru) 1980-02-29
FI62301C (fi) 1982-12-10
ES425936A1 (es) 1976-09-16
NL7404811A (xx) 1974-11-05
DE2421548A1 (de) 1974-11-21
GB1419994A (en) 1976-01-07
IE40014B1 (en) 1979-02-28
CA1041108A (en) 1978-10-24
HU168863B (xx) 1976-07-28
IL44526A0 (en) 1974-06-30
IE40014L (en) 1974-11-03
FR2227869B1 (xx) 1978-07-21
FR2227869A1 (xx) 1974-11-29
IL44526A (en) 1979-05-31
IN138721B (xx) 1976-03-20
SE416299B (sv) 1980-12-15
AU477220B2 (en) 1976-10-21

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITH KLINE & FRENCH LABORATORIES LTD

Effective date: 19850422