BE808504A - 2-Acylamino-benzimidazole derivs - antihypertensives and anthelmintics, produced by acylation of 2-aminobenzimidazoles - Google Patents

2-Acylamino-benzimidazole derivs - antihypertensives and anthelmintics, produced by acylation of 2-aminobenzimidazoles

Info

Publication number
BE808504A
BE808504A BE138756A BE138756A BE808504A BE 808504 A BE808504 A BE 808504A BE 138756 A BE138756 A BE 138756A BE 138756 A BE138756 A BE 138756A BE 808504 A BE808504 A BE 808504A
Authority
BE
Belgium
Prior art keywords
acylation
aminobenzimidazoles
anthelmintics
antihypertensives
acylamino
Prior art date
Application number
BE138756A
Other languages
French (fr)
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of BE808504A publication Critical patent/BE808504A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The novel title cpds of formula (I): (where n is 2-4, R is H or 2-4C aliphatic acyl, R1 is 1-4C alkyl, 2-6C aliphatic acyl, or when n is 3 or 4, R1 may also be H, R2 is 2-4C aliphatic acyl, and R3 is lower alkoxy) and their acid addn salts are prepd. by acylation of the corresp. cpds. in which R2 is H, using acylating agents of formula R2X (where X is halogen or R2O). (I) have low toxicity and may be administered orally or parenterally in daily doses of 0.1-50 mg/kg.
BE138756A 1972-12-12 1973-12-11 2-Acylamino-benzimidazole derivs - antihypertensives and anthelmintics, produced by acylation of 2-aminobenzimidazoles BE808504A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT3275772 1972-12-12

Publications (1)

Publication Number Publication Date
BE808504A true BE808504A (en) 1974-03-29

Family

ID=11235612

Family Applications (1)

Application Number Title Priority Date Filing Date
BE138756A BE808504A (en) 1972-12-12 1973-12-11 2-Acylamino-benzimidazole derivs - antihypertensives and anthelmintics, produced by acylation of 2-aminobenzimidazoles

Country Status (1)

Country Link
BE (1) BE808504A (en)

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