BE788479A - Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques - Google Patents

Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques

Info

Publication number
BE788479A
BE788479A BE788479DA BE788479A BE 788479 A BE788479 A BE 788479A BE 788479D A BE788479D A BE 788479DA BE 788479 A BE788479 A BE 788479A
Authority
BE
Belgium
Prior art keywords
tetracyclines
aminomethane
hydroxymethyl
complexes
tris
Prior art date
Application number
Other languages
English (en)
French (fr)
Inventor
I Kahan-Nee-Laszlo
Original Assignee
Medimpex Gyogyszerkulkereskede
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE788479A publication Critical patent/BE788479A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE788479D 1971-09-06 Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques BE788479A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4153371A GB1401178A (en) 1971-09-06 1971-09-06 Complexes of tetracyclines

Publications (1)

Publication Number Publication Date
BE788479A true BE788479A (fr) 1973-01-02

Family

ID=10420133

Family Applications (1)

Application Number Title Priority Date Filing Date
BE788479D BE788479A (fr) 1971-09-06 Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques

Country Status (10)

Country Link
US (1) US4418060A (enExample)
JP (1) JPS587610B2 (enExample)
BE (1) BE788479A (enExample)
CS (1) CS226153B2 (enExample)
DE (1) DE2243776C2 (enExample)
FR (1) FR2154464B1 (enExample)
GB (1) GB1401178A (enExample)
HK (1) HK58877A (enExample)
PL (1) PL83459B1 (enExample)
YU (1) YU225972A (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788479A (fr) 1971-09-06 1973-01-02 Medimpex Gyogyszerkulkereskede Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques
DK1676579T3 (da) * 1998-05-08 2009-03-16 Univ Miami Anvendelse af sub-antimikrobielle tetracykliner til behandling af okulær rosacea
US6346547B1 (en) 1999-02-08 2002-02-12 Checkpoint, Genetics, Inc. N-substituted amino acids, antioxidant pharmaceutical compositions containing n-substituted amino acids and methods for preventing cardiovascular diseases and/or preventing and/or treating antioxidant responsive diseases therewith
NZ544826A (en) * 2003-07-25 2008-07-31 Warner Chilcott Co Inc A doxycycline metal complex in a solid dosage form
KR101171408B1 (ko) 2004-05-21 2012-08-08 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 테트라사이클린 및 이의 유사체의 합성
AU2006206359B2 (en) * 2005-01-21 2011-03-31 Allergan Pharmaceuticals International Limited A tetracycline metal complex in a solid dosage form
JP5335664B2 (ja) * 2006-04-07 2013-11-06 プレジデント アンド フェロウズ オブ ハーバード カレッジ テトラサイクリンおよびその類似体の合成
EP2479169B1 (en) 2006-10-11 2014-12-03 President and Fellows of Harvard College Synthesis of Enone Intermediate
WO2010126607A2 (en) 2009-04-30 2010-11-04 President And Fellows Of Harvard College Synthesis of tetracyclines and intermediates thereto

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754346A (fr) * 1969-08-06 1971-01-18 Bru Jean Composition pharmaceutique a base de tetracycline presentee sous une forme effervescente
BE788479A (fr) 1971-09-06 1973-01-02 Medimpex Gyogyszerkulkereskede Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques

Also Published As

Publication number Publication date
FR2154464A1 (enExample) 1973-05-11
US4418060A (en) 1983-11-29
CS226153B2 (en) 1984-03-19
DE2243776C2 (de) 1983-01-27
DE2243776A1 (de) 1973-03-22
PL83459B1 (enExample) 1975-12-31
HK58877A (en) 1977-12-02
YU225972A (en) 1982-02-28
FR2154464B1 (enExample) 1975-10-31
GB1401178A (en) 1975-07-16
JPS4861610A (enExample) 1973-08-29
JPS587610B2 (ja) 1983-02-10

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: MEDIMPEX GYOGYSZERKULKERESKEDELMI VALLALAT

Effective date: 19870930