BE783044A - Nouvelles thieno(3,2-d) pyrimidines - Google Patents

Nouvelles thieno(3,2-d) pyrimidines

Info

Publication number
BE783044A
BE783044A BE783044A BE783044A BE783044A BE 783044 A BE783044 A BE 783044A BE 783044 A BE783044 A BE 783044A BE 783044 A BE783044 A BE 783044A BE 783044 A BE783044 A BE 783044A
Authority
BE
Belgium
Prior art keywords
thieno
pyrimidines
news
news thieno
Prior art date
Application number
BE783044A
Other languages
English (en)
French (fr)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de
Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de
Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of BE783044A publication Critical patent/BE783044A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE783044A 1971-05-04 1972-05-04 Nouvelles thieno(3,2-d) pyrimidines BE783044A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712121950 DE2121950A1 (en) 1971-05-04 1971-05-04 Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de) 1971-07-26 1971-07-26 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de) 1972-03-29 1972-03-29 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
BE783044A true BE783044A (fr) 1972-11-06

Family

ID=27183398

Family Applications (1)

Application Number Title Priority Date Filing Date
BE783044A BE783044A (fr) 1971-05-04 1972-05-04 Nouvelles thieno(3,2-d) pyrimidines

Country Status (15)

Country Link
US (1) US3888851A (en:Method)
AT (1) AT318619B (en:Method)
AU (1) AU4181572A (en:Method)
BE (1) BE783044A (en:Method)
BG (1) BG20593A3 (en:Method)
DD (1) DD97656A5 (en:Method)
DK (1) DK129844B (en:Method)
ES (1) ES402302A1 (en:Method)
FR (1) FR2135294B1 (en:Method)
GB (1) GB1393161A (en:Method)
HU (1) HU163960B (en:Method)
IL (1) IL39341A (en:Method)
NL (1) NL7206041A (en:Method)
PL (1) PL82381B1 (en:Method)
RO (1) RO62428A (en:Method)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
FI943798A0 (fi) * 1992-02-19 1994-08-18 Pfizer Kasvaimenvastaisen vaikutuksen lisäämiseen tarkoitettuja heterosyklisiä yhdisteitä
KR100378937B1 (ko) 1997-10-20 2003-05-09 에프. 호프만-라 로슈 아게 바이사이클릭 키나아제 억제제
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
BRPI0608387A2 (pt) * 2006-04-19 2009-12-29 Boehringer Ingelheim Int compostos para o tratamento de doenças inflamatórias
CL2007001166A1 (es) 2006-04-26 2008-01-25 Piramed Ltd Compuestos derivados de pirimidina condensada, inhibidores de pi3-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicion farmaceutica
CN101472930B (zh) 2006-04-26 2011-12-14 霍夫曼-拉罗奇有限公司 用作PI3K抑制剂的噻吩并[3,2-d]嘧啶的衍生物
PT2041139E (pt) 2006-04-26 2012-01-13 Hoffmann La Roche Compostos farmacêuticos
BRPI0717923A2 (pt) 2006-12-07 2013-10-22 Genentech In '' composto, composição farmacêutica, método para tratar um câncer, processo para a produção de uma composição farmacêutica, usos, métodos para inibir ou modular a atividade da lipídeo quinase e kit ' '
ZA200904531B (en) 2006-12-07 2010-09-29 Hoffmann La Roche Phosphoinositide 3-kinase inhibitor compounds and methods of use
EP2207781B1 (en) 2007-09-24 2012-11-28 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
NZ585348A (en) * 2007-10-19 2012-02-24 Boehringer Ingelheim Int Heterocycle-substituted piperazino-dihydrothienopyrimidines
EP2214675B1 (en) 2007-10-25 2013-11-20 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
AU2010224125B2 (en) 2009-03-12 2015-05-14 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
WO2010136491A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
EP2435438A1 (en) 2009-05-27 2012-04-04 Genentech, Inc. Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
WO2011130654A1 (en) 2010-04-16 2011-10-20 Genentech, Inc. Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
MX369175B (es) 2013-02-25 2019-10-30 Genentech Inc Métodos para detectar mutantes de akt resistentes a fármacos.
GB201410816D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) * 1964-09-29 1965-10-05 Ciba Geigy Corp Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

Also Published As

Publication number Publication date
GB1393161A (en) 1975-05-07
DK129844C (en:Method) 1975-05-12
FR2135294A1 (en:Method) 1972-12-15
IL39341A (en) 1975-08-31
AT318619B (de) 1974-11-11
IL39341A0 (en) 1972-07-26
FR2135294B1 (en:Method) 1975-10-17
DD97656A5 (en:Method) 1973-05-12
NL7206041A (en:Method) 1972-11-07
ES402302A1 (es) 1975-04-01
RO62428A (fr) 1978-01-15
BG20593A3 (bg) 1975-12-05
US3888851A (en) 1975-06-10
PL82381B1 (en:Method) 1975-10-31
AU4181572A (en) 1973-11-08
HU163960B (en:Method) 1973-11-28
DK129844B (da) 1974-11-25

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