BE778771A - Preparation de derives de la pyridine trisubstituee - Google Patents

Preparation de derives de la pyridine trisubstituee

Info

Publication number
BE778771A
BE778771A BE778771A BE778771A BE778771A BE 778771 A BE778771 A BE 778771A BE 778771 A BE778771 A BE 778771A BE 778771 A BE778771 A BE 778771A BE 778771 A BE778771 A BE 778771A
Authority
BE
Belgium
Prior art keywords
trisubstitute
pyridine
derivatives
preparation
pyridine trisubstitute
Prior art date
Application number
BE778771A
Other languages
English (en)
Inventor
W E Barth
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE778771A publication Critical patent/BE778771A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE778771A 1971-02-16 1972-02-01 Preparation de derives de la pyridine trisubstituee BE778771A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11587871A 1971-02-16 1971-02-16
US25664172A 1972-05-25 1972-05-25

Publications (1)

Publication Number Publication Date
BE778771A true BE778771A (fr) 1972-08-01

Family

ID=26813670

Family Applications (1)

Application Number Title Priority Date Filing Date
BE778771A BE778771A (fr) 1971-02-16 1972-02-01 Preparation de derives de la pyridine trisubstituee

Country Status (9)

Country Link
US (2) US3700681A (fr)
AT (1) AT315842B (fr)
BE (1) BE778771A (fr)
CA (1) CA978962A (fr)
CH (1) CH541560A (fr)
DE (2) DE2265581C2 (fr)
FR (1) FR2125309B1 (fr)
GB (2) GB1367669A (fr)
NL (1) NL174349C (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR207639A1 (es) * 1973-12-26 1976-10-22 Pfizer Un procedimiento para preparar pirido (3,2-d)1,3-dioxin-6-epoxietanos y compuestos intermediarios desprovistos de actividad terapeutica
US3952101A (en) * 1975-04-14 1976-04-20 Smithkline Corporation α-Amino methyl-5-hydroxy-2-pyridinemethanols
US4011231A (en) * 1975-10-03 1977-03-08 Pfizer Inc. 2-Phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin maleate and its use as an intermediate
SE7708307L (sv) * 1976-08-26 1978-02-27 Pfizer Forfarande for framstellning av farmaceutiska kompositioner anvendbara sasom bronkodilatorer
US4175128A (en) * 1979-01-03 1979-11-20 Pfizer Inc. Method for treating congestive heart failure
US4632992A (en) * 1981-02-09 1986-12-30 Pfizer Inc. Intermediates for preparing pirbuterol and analogs
SU1194273A3 (ru) * 1981-02-09 1985-11-23 Пфайзер Инк (Фирма) Способ получени пирбутерола или его аналогов
GB8414559D0 (en) * 1984-06-07 1984-07-11 Scras Pyridine derivatives
EP0220054A3 (fr) * 1985-10-16 1987-12-02 Glaxo Group Limited Dérivés d'éthanolamine
US4601897A (en) * 1985-11-06 1986-07-22 Pfizer Inc. Prazosin-pirbuterol combination for bronchodilation
AU2305092A (en) * 1991-06-26 1993-01-25 Sepracor, Inc. Methods and compositions for treating pulmonary and cardiac disorders using optically pure (+) pirbuterol
AU2270092A (en) * 1991-06-26 1993-01-25 Sepracor, Inc. Methods and compositions for treating pulmonary and cardiac disorders using optically pure (-)pirbuterol
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
RU2387646C2 (ru) * 2003-08-29 2010-04-27 Рэнбакси Лабораториз Лимитед Ингибиторы фосфодиэстеразы типа-iv
EP1694655A2 (fr) * 2003-11-26 2006-08-30 Ranbaxy Laboratories Limited Inhibiteurs de la phosphodiesterase
WO2005092860A1 (fr) * 2004-03-23 2005-10-06 Pfizer Limited Composes servant au traitement de maladies
US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
BRPI0617673C1 (pt) * 2005-10-19 2012-05-22 Ranbaxy Lab Ltd composições de inibidores de fosfodiesterase do tipo iv
JP2009512676A (ja) 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ムスカリン性受容体アンタゴニストの医薬組成物
MX2009001963A (es) * 2006-08-22 2009-03-30 Ranbaxy Lab Ltd Inhibidores de metaloproteinasa de matriz.
WO2008035316A2 (fr) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Inhibiteurs de phosphodiestérase
MX2009003100A (es) * 2006-09-22 2009-05-11 Ranbaxy Lab Ltd Inhibidores de fosfodiesterasa tipo iv.
US20080207659A1 (en) * 2007-02-15 2008-08-28 Asit Kumar Chakraborti Inhibitors of phosphodiesterase type 4
JP5671236B2 (ja) 2007-03-14 2015-02-18 ランバクシー ラボラトリーズ リミテッド ホスホジエステラーゼ阻害剤としてのピラゾロ（３，４−ｂ）ピリジン誘導体
US20110130403A1 (en) * 2007-03-14 2011-06-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
EP2111861A1 (fr) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions d'inhibiteurs de type IV de la phosphodiestérase
CA2807097A1 (fr) 2010-07-30 2012-02-02 Ranbaxy Laboratories Limited Inhibiteurs de metalloproteinase de matrice
AU2011306396A1 (en) 2010-09-24 2013-05-02 Ranbaxy Laboratories Limited Matrix metalloproteinase inhibitors
CN103848781B (zh) * 2012-11-30 2017-06-30 重庆华邦制药有限公司 高选择性氧化二羟甲基吡啶中一个羟甲基的方法
MX368898B (es) 2012-12-03 2019-10-21 Pfizer Moduladores selectivos del receptor de androgenos novedosos.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1089189A (en) * 1964-09-23 1967-11-01 Koninklijke Pharma Fab Nv Ethers of -(2-pyridyl)benzyl alcohols

Also Published As

Publication number Publication date
NL174349B (nl) 1984-01-02
DE2265581C2 (de) 1982-07-01
US3700681A (en) 1972-10-24
NL174349C (nl) 1984-06-01
CH541560A (fr) 1973-10-31
DE2204195A1 (de) 1972-08-17
FR2125309B1 (fr) 1976-05-14
DE2204195C2 (de) 1981-11-19
AT315842B (de) 1974-06-10
US3763173A (en) 1973-10-02
GB1367668A (en) 1974-09-18
NL7201471A (fr) 1972-08-18
CA978962A (en) 1975-12-02
FR2125309A1 (fr) 1972-09-29
GB1367669A (en) 1974-09-18

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: PFIZER INC.

Effective date: 19920201