BE778508A - Carbamates de cephalosporine et leur obtention - Google Patents

Carbamates de cephalosporine et leur obtention

Info

Publication number
BE778508A
BE778508A BE778508A BE778508A BE778508A BE 778508 A BE778508 A BE 778508A BE 778508 A BE778508 A BE 778508A BE 778508 A BE778508 A BE 778508A BE 778508 A BE778508 A BE 778508A
Authority
BE
Belgium
Prior art keywords
cephalosporin
carbamates
obtaining
cephalosporin carbamates
Prior art date
Application number
BE778508A
Other languages
English (en)
Inventor
B G Christensen
L D Cama
J A Kern
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of BE778508A publication Critical patent/BE778508A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/577-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE778508A 1971-01-27 1972-01-26 Carbamates de cephalosporine et leur obtention BE778508A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB329571A GB1350772A (en) 1971-01-27 1971-01-27 Antibiotics and processes for their production
GB2852271 1971-06-17
GB3965471 1971-08-24
GB182972 1972-01-14

Publications (1)

Publication Number Publication Date
BE778508A true BE778508A (fr) 1972-07-26

Family

ID=27447180

Family Applications (1)

Application Number Title Priority Date Filing Date
BE778508A BE778508A (fr) 1971-01-27 1972-01-26 Carbamates de cephalosporine et leur obtention

Country Status (10)

Country Link
JP (1) JPS5418274B1 (fr)
AR (1) AR204899A1 (fr)
AU (1) AU468248B2 (fr)
BE (1) BE778508A (fr)
CA (1) CA1003404A (fr)
CH (1) CH569021A5 (fr)
DE (1) DE2203653C3 (fr)
FR (1) FR2161866B1 (fr)
GB (1) GB1350772A (fr)
IE (1) IE36192B1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905963A (en) * 1972-01-25 1975-09-16 Lilly Co Eli Process for preparing primary 3-carbamoyloxymethyl cephalosporins
US3994875A (en) * 1974-06-24 1976-11-30 Yeda Research & Development Co. Ltd. Antibiotics
CA2109084C (fr) * 1991-05-03 2004-02-24 John William Fisher Costerton Methode de destruction de films biologiques
WO2004083217A1 (fr) * 2003-03-20 2004-09-30 Orchid Chemicals & Pharmaceuticals Ltd Procede ameliore de preparation de cefoxitine
CN101830913B (zh) * 2010-04-09 2012-10-31 烟台宝华生物技术有限公司 头孢母核衍生化合物、由其制备的头孢烯类鎓盐化合物及采用其制备硫酸头孢吡唑的方法
CN103848851B (zh) * 2012-11-29 2016-03-02 上海交通大学 一种盐酸头孢卡品酯的合成方法
US20220096721A1 (en) 2019-01-29 2022-03-31 Nipro Corporation Artificial lung device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1445633A1 (de) 1963-10-07 1968-12-05 Ciba Geigy Verfahren zur Herstellung neuer Amide
CH480365A (de) * 1965-01-18 1969-10-31 Ciba Geigy Verfahren zur Herstellung neuer Derivate der 7-Aminocephalosporansäure

Also Published As

Publication number Publication date
IE36192B1 (en) 1976-09-15
DE2203653B2 (de) 1974-12-19
DE2203653C3 (de) 1975-07-31
CH569021A5 (fr) 1975-11-14
CA1003404A (en) 1977-01-11
AU3835672A (en) 1973-08-02
GB1350772A (en) 1974-04-24
DE2203653A1 (de) 1972-08-10
JPS5418274B1 (fr) 1979-07-06
FR2161866A1 (fr) 1973-07-13
AU468248B2 (en) 1976-01-08
AR204899A1 (es) 1976-03-19
FR2161866B1 (fr) 1975-08-01
IE36192L (en) 1972-07-27

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