BE658691A - - Google Patents
Info
- Publication number
- BE658691A BE658691A BE658691A BE658691A BE658691A BE 658691 A BE658691 A BE 658691A BE 658691 A BE658691 A BE 658691A BE 658691 A BE658691 A BE 658691A BE 658691 A BE658691 A BE 658691A
- Authority
- BE
- Belgium
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/373—Halogenated derivatives with all hydroxy groups on non-condensed rings and with unsaturation outside the aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33957864A | 1964-01-23 | 1964-01-23 | |
| US35184264A | 1964-03-13 | 1964-03-13 | |
| US41163264A | 1964-11-16 | 1964-11-16 | |
| US512514A US3277106A (en) | 1964-01-23 | 1965-12-08 | Tetrahydronaphthalene and benzosuberane compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE658691A true BE658691A (de) | 1965-07-22 |
Family
ID=27502608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE658691A BE658691A (de) | 1964-01-23 | 1965-01-22 |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US3522319A (de) |
| BE (1) | BE658691A (de) |
| NL (1) | NL6500840A (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0703228A1 (de) * | 1994-09-20 | 1996-03-27 | Eli Lilly And Company | Naphthyl-Derivate, Zwischenprodukte, Verfahren, Zusammensetzungen, die sie enthalten |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3919327A (en) * | 1963-07-03 | 1975-11-11 | Upjohn Co | Phenolic diphenylbenzocycloalkenes |
| US3875242A (en) * | 1968-01-02 | 1975-04-01 | Upjohn Co | Compounds and process for preparing the same |
| US3869550A (en) * | 1972-05-01 | 1975-03-04 | Environmental Science Corp | Method for the control of fertility |
| US4486609A (en) * | 1981-03-16 | 1984-12-04 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
| US4933475A (en) * | 1980-09-19 | 1990-06-12 | Pfizer, Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
| US4739079A (en) * | 1980-09-19 | 1988-04-19 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
| US4593131A (en) * | 1980-09-19 | 1986-06-03 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
| US4835192A (en) * | 1980-09-19 | 1989-05-30 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| UA51676C2 (uk) * | 1995-11-02 | 2002-12-16 | Пфайзер Інк. | (-)цис-6(s)-феніл-5(r)[4-(2-піролідин-1-ілетокси)феніл]-5,6,7,8-тетрагідронафталін-2-ол d-тартрат, спосіб його одержання, спосіб лікування захворювань, що піддаються лікуванню агоністами естрогену, та фармацевтична композиція |
| IL120266A (en) * | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
| HN1996000101A (es) | 1996-02-28 | 1997-06-26 | Inc Pfizer | Terapia combinada para la osteoporosis |
| ID19392A (id) * | 1996-08-29 | 1998-07-09 | Lilly Co Eli | Senyawa naftil dan bahan pertengahan serta komposisi dan metode penggunaan |
| AU747690B2 (en) * | 1996-08-29 | 2002-05-16 | Eli Lilly And Company | Naphthyl intermediates |
| JP2003521468A (ja) | 1999-03-17 | 2003-07-15 | シグナル ファーマシューティカルズ， インコーポレイテッド | エストロゲンレセプタを変調させるための化合物及び方法 |
| US6593322B1 (en) * | 1999-03-17 | 2003-07-15 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
| YU26700A (sh) | 1999-05-24 | 2002-06-19 | Pfizer Products Inc. | Postupak za cis-1-(2-(4-(6-metoksi-2-fenil-1,2,3,4- tetrahidronaftalen-1-il)fenoksi)etil)pirolidin |
| EP1113007A1 (de) * | 1999-12-24 | 2001-07-04 | Pfizer Inc. | Tetrahydroisochinolin-Verbindungen zur Verwendung als Östrogen-Agonisten/-Antagonisten |
| JP2004510693A (ja) * | 2000-04-07 | 2004-04-08 | ファイザー・プロダクツ・インク | エストロゲンアゴニスト／アンタゴニスト代謝物 |
| DE602006017217D1 (de) * | 2005-06-22 | 2010-11-11 | Pfizer Prod Inc | Stereoselektives hydrierverfahren zur herstellung von cis-6-phenyl-5-ä4-(2-pyrrolidin-1-yl-ethoxy)-phenylü-2-methoxy-5,6,7,8-tetrahydronaphthalin-hydrochlorid |
| WO2011159769A2 (en) | 2010-06-17 | 2011-12-22 | Aragon Pharmaceuticals, Inc. | Indane estrogen receptor modulators and uses thereof |
| WO2023023531A1 (en) * | 2021-08-20 | 2023-02-23 | Biotheryx, Inc. | Estrogen receptor degraders, pharmaceutical compositions, and therapeutic applications |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2444233A (en) * | 1944-02-09 | 1948-06-29 | United Gas Improvement Co | Process for reacting an alkylated indene with a phenolic compound |
| US3293263A (en) * | 1963-12-09 | 1966-12-20 | Upjohn Co | Diphenylbenzocycloalkenes |
-
1964
- 1964-03-13 US US351842A patent/US3522319A/en not_active Expired - Lifetime
-
1965
- 1965-01-22 BE BE658691A patent/BE658691A/xx unknown
- 1965-01-22 NL NL6500840A patent/NL6500840A/xx unknown
- 1965-12-08 US US512514A patent/US3277106A/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0703228A1 (de) * | 1994-09-20 | 1996-03-27 | Eli Lilly And Company | Naphthyl-Derivate, Zwischenprodukte, Verfahren, Zusammensetzungen, die sie enthalten |
Also Published As
| Publication number | Publication date |
|---|---|
| US3277106A (en) | 1966-10-04 |
| US3522319A (en) | 1970-07-28 |
| NL6500840A (de) | 1965-07-26 |