BE639393A - - Google Patents
Info
- Publication number
- BE639393A BE639393A BE639393DA BE639393A BE 639393 A BE639393 A BE 639393A BE 639393D A BE639393D A BE 639393DA BE 639393 A BE639393 A BE 639393A
- Authority
- BE
- Belgium
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23421362A | 1962-10-30 | 1962-10-30 | |
| US311291A US3300494A (en) | 1962-10-30 | 1963-09-27 | Pyrazinamidoguanidine products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE639393A true BE639393A (es) |
Family
ID=26927676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE639393D BE639393A (es) | 1962-10-30 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3300494A (es) |
| BE (1) | BE639393A (es) |
| BR (1) | BR6353917D0 (es) |
| CH (2) | CH471798A (es) |
| CY (1) | CY535A (es) |
| DE (1) | DE1470052A1 (es) |
| DK (2) | DK108864C (es) |
| FR (1) | FR1552762A (es) |
| GB (2) | GB1067473A (es) |
| MY (1) | MY7000080A (es) |
| NL (1) | NL299929A (es) |
| SE (3) | SE319179B (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1795438B1 (de) * | 1962-10-30 | 1973-09-06 | Merck & Co Inc | 3,0-Diamino-6-chlor-pyrazincarbonsaeuremethylester und Verfahren zu dessen Herstellung |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6501301A (es) * | 1964-04-03 | 1965-10-04 | ||
| US3455919A (en) * | 1966-09-01 | 1969-07-15 | Merck & Co Inc | 5-dechlorination of 3-amino-5,6-dichloropyrazinoyl compounds |
| US3507865A (en) * | 1967-04-27 | 1970-04-21 | Merck & Co Inc | 3-hydroxy- and 3-mercaptopyrazinamidoguanidines the corresponding ethers and thioethers and processes for their preparation |
| US3539569A (en) * | 1968-08-21 | 1970-11-10 | Merck & Co Inc | Preparation of pyrazinoylguanidines from pyrazinoylureas |
| US4085211A (en) * | 1975-12-15 | 1978-04-18 | Merck & Co., Inc. | Pyrazinecarboxamides and processes for preparing same |
| US4087526A (en) * | 1976-07-23 | 1978-05-02 | Merck & Co., Inc. | (3-Amino-5-substituted-6-fluoropyrazinoyl or pyrazamido)-guanidines and their derivatives bearing substituents on the guanidino nitrogens |
| US4224447A (en) * | 1979-03-27 | 1980-09-23 | Merck & Co., Inc. | Novel pyrazinecarboxamides and processes for preparing same |
| US4604394A (en) * | 1984-10-01 | 1986-08-05 | Merck & Co., Inc. | Antiarrhythmic compositions and method |
| GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
| IN172842B (es) * | 1990-05-17 | 1993-12-11 | Boots Pharmaceuticals Limited | |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US20070021439A1 (en) * | 2005-07-25 | 2007-01-25 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| US9593084B2 (en) | 2012-12-17 | 2017-03-14 | Parion Sciences, Inc. | Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity |
| WO2014099673A1 (en) | 2012-12-17 | 2014-06-26 | Parion Sciences, Inc. | 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1672029A (en) * | 1924-08-05 | 1928-06-05 | C A F Kahlbaum Chem Fab G M B | Process for the production of amidoguanidines and their alkyl derivatives |
| US2408694A (en) * | 1942-05-29 | 1946-10-01 | Libbey Owens Ford Glass Co | Method of preparing acyl guanidines |
-
0
- NL NL299929D patent/NL299929A/xx unknown
- BE BE639393D patent/BE639393A/xx unknown
-
1963
- 1963-09-27 US US311291A patent/US3300494A/en not_active Expired - Lifetime
- 1963-10-15 GB GB40659/63A patent/GB1067473A/en not_active Expired
- 1963-10-15 GB GB20928/66A patent/GB1067474A/en not_active Expired
- 1963-10-22 BR BR153917/63A patent/BR6353917D0/pt unknown
- 1963-10-28 DE DE19631470052 patent/DE1470052A1/de active Pending
- 1963-10-29 SE SE11900/63A patent/SE319179B/xx unknown
- 1963-10-29 FR FR1552762D patent/FR1552762A/fr not_active Expired
- 1963-10-29 SE SE01719/65A patent/SE334614B/xx unknown
- 1963-10-30 CH CH674867A patent/CH471798A/de not_active IP Right Cessation
- 1963-10-30 DK DK476864AA patent/DK108864C/da active
- 1963-10-30 DK DK512163AA patent/DK108310C/da active
- 1963-10-30 CH CH1330063A patent/CH454879A/de unknown
-
1968
- 1968-10-11 SE SE13738/68A patent/SE348734B/xx unknown
-
1970
- 1970-04-10 CY CY53570A patent/CY535A/xx unknown
- 1970-12-31 MY MY197080A patent/MY7000080A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1795438B1 (de) * | 1962-10-30 | 1973-09-06 | Merck & Co Inc | 3,0-Diamino-6-chlor-pyrazincarbonsaeuremethylester und Verfahren zu dessen Herstellung |
Also Published As
| Publication number | Publication date |
|---|---|
| DK108864C (da) | 1968-02-19 |
| BR6353917D0 (pt) | 1973-07-12 |
| DE1470052A1 (de) | 1969-02-13 |
| CY535A (en) | 1970-04-10 |
| MY7000080A (en) | 1970-12-31 |
| SE319179B (es) | 1970-01-12 |
| GB1067474A (en) | 1967-05-03 |
| SE334614B (es) | 1971-05-03 |
| CH454879A (de) | 1968-04-30 |
| SE348734B (es) | 1972-09-11 |
| CH471798A (de) | 1969-04-30 |
| NL299929A (es) | |
| GB1067473A (en) | 1967-05-03 |
| FR1552762A (es) | 1969-01-10 |
| US3300494A (en) | 1967-01-24 |
| DK108310C (da) | 1967-11-13 |