DK108864C - Fremgangsmåde til fremstilling af (3-aminopyrazinamido)- guanider eller syreadditionssalte deraf. - Google Patents
Fremgangsmåde til fremstilling af (3-aminopyrazinamido)- guanider eller syreadditionssalte deraf.Info
- Publication number
- DK108864C DK108864C DK476864AA DK476864A DK108864C DK 108864 C DK108864 C DK 108864C DK 476864A A DK476864A A DK 476864AA DK 476864 A DK476864 A DK 476864A DK 108864 C DK108864 C DK 108864C
- Authority
- DK
- Denmark
- Prior art keywords
- aminopyrazinamido
- guanides
- preparation
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23421362A | 1962-10-30 | 1962-10-30 | |
US311291A US3300494A (en) | 1962-10-30 | 1963-09-27 | Pyrazinamidoguanidine products |
Publications (1)
Publication Number | Publication Date |
---|---|
DK108864C true DK108864C (da) | 1968-02-19 |
Family
ID=26927676
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK512163AA DK108310C (da) | 1962-10-30 | 1963-10-30 | Fremgangsmåde til fremstilling af (3-aminopyrazinamido)-guanidinforbindelser eller syreadditionssalte heraf. |
DK476864AA DK108864C (da) | 1962-10-30 | 1963-10-30 | Fremgangsmåde til fremstilling af (3-aminopyrazinamido)- guanider eller syreadditionssalte deraf. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK512163AA DK108310C (da) | 1962-10-30 | 1963-10-30 | Fremgangsmåde til fremstilling af (3-aminopyrazinamido)-guanidinforbindelser eller syreadditionssalte heraf. |
Country Status (12)
Country | Link |
---|---|
US (1) | US3300494A (es) |
BE (1) | BE639393A (es) |
BR (1) | BR6353917D0 (es) |
CH (2) | CH471798A (es) |
CY (1) | CY535A (es) |
DE (1) | DE1470052A1 (es) |
DK (2) | DK108310C (es) |
FR (1) | FR1552762A (es) |
GB (2) | GB1067473A (es) |
MY (1) | MY7000080A (es) |
NL (1) | NL299929A (es) |
SE (3) | SE319179B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL299931A (es) * | 1962-10-30 | |||
NL6501301A (es) * | 1964-04-03 | 1965-10-04 | ||
US3455919A (en) * | 1966-09-01 | 1969-07-15 | Merck & Co Inc | 5-dechlorination of 3-amino-5,6-dichloropyrazinoyl compounds |
US3507865A (en) * | 1967-04-27 | 1970-04-21 | Merck & Co Inc | 3-hydroxy- and 3-mercaptopyrazinamidoguanidines the corresponding ethers and thioethers and processes for their preparation |
US3539569A (en) * | 1968-08-21 | 1970-11-10 | Merck & Co Inc | Preparation of pyrazinoylguanidines from pyrazinoylureas |
US4085211A (en) * | 1975-12-15 | 1978-04-18 | Merck & Co., Inc. | Pyrazinecarboxamides and processes for preparing same |
US4087526A (en) * | 1976-07-23 | 1978-05-02 | Merck & Co., Inc. | (3-Amino-5-substituted-6-fluoropyrazinoyl or pyrazamido)-guanidines and their derivatives bearing substituents on the guanidino nitrogens |
US4224447A (en) * | 1979-03-27 | 1980-09-23 | Merck & Co., Inc. | Novel pyrazinecarboxamides and processes for preparing same |
US4604394A (en) * | 1984-10-01 | 1986-08-05 | Merck & Co., Inc. | Antiarrhythmic compositions and method |
GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
IN172842B (es) * | 1990-05-17 | 1993-12-11 | Boots Pharmaceuticals Limited | |
US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
US20070021439A1 (en) * | 2005-07-25 | 2007-01-25 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers |
AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
MX2015007796A (es) | 2012-12-17 | 2015-09-04 | Parion Sciences Inc | Derivados de cloro-pirazin carboxamida con actividad bloqueadora sobre los canales de sodio epiteliales. |
KR20150095870A (ko) | 2012-12-17 | 2015-08-21 | 패리온 사이언스 인코퍼레이티드 | 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물 |
US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1672029A (en) * | 1924-08-05 | 1928-06-05 | C A F Kahlbaum Chem Fab G M B | Process for the production of amidoguanidines and their alkyl derivatives |
US2408694A (en) * | 1942-05-29 | 1946-10-01 | Libbey Owens Ford Glass Co | Method of preparing acyl guanidines |
-
0
- NL NL299929D patent/NL299929A/xx unknown
- BE BE639393D patent/BE639393A/xx unknown
-
1963
- 1963-09-27 US US311291A patent/US3300494A/en not_active Expired - Lifetime
- 1963-10-15 GB GB40659/63A patent/GB1067473A/en not_active Expired
- 1963-10-15 GB GB20928/66A patent/GB1067474A/en not_active Expired
- 1963-10-22 BR BR153917/63A patent/BR6353917D0/pt unknown
- 1963-10-28 DE DE19631470052 patent/DE1470052A1/de active Pending
- 1963-10-29 SE SE11900/63A patent/SE319179B/xx unknown
- 1963-10-29 SE SE01719/65A patent/SE334614B/xx unknown
- 1963-10-29 FR FR1552762D patent/FR1552762A/fr not_active Expired
- 1963-10-30 CH CH674867A patent/CH471798A/de not_active IP Right Cessation
- 1963-10-30 CH CH1330063A patent/CH454879A/de unknown
- 1963-10-30 DK DK512163AA patent/DK108310C/da active
- 1963-10-30 DK DK476864AA patent/DK108864C/da active
-
1968
- 1968-10-11 SE SE13738/68A patent/SE348734B/xx unknown
-
1970
- 1970-04-10 CY CY53570A patent/CY535A/xx unknown
- 1970-12-31 MY MY197080A patent/MY7000080A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US3300494A (en) | 1967-01-24 |
CH454879A (de) | 1968-04-30 |
CY535A (en) | 1970-04-10 |
NL299929A (es) | |
MY7000080A (en) | 1970-12-31 |
GB1067474A (en) | 1967-05-03 |
SE348734B (es) | 1972-09-11 |
DK108310C (da) | 1967-11-13 |
FR1552762A (es) | 1969-01-10 |
BR6353917D0 (pt) | 1973-07-12 |
SE319179B (es) | 1970-01-12 |
DE1470052A1 (de) | 1969-02-13 |
GB1067473A (en) | 1967-05-03 |
BE639393A (es) | |
SE334614B (es) | 1971-05-03 |
CH471798A (de) | 1969-04-30 |
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