BE571821A - - Google Patents
Info
- Publication number
- BE571821A BE571821A BE571821DA BE571821A BE 571821 A BE571821 A BE 571821A BE 571821D A BE571821D A BE 571821DA BE 571821 A BE571821 A BE 571821A
- Authority
- BE
- Belgium
- Prior art keywords
- compound
- formula
- sep
- hydroxyethyl
- benzyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims description 19
- 229960002327 Chloral Hydrate Drugs 0.000 claims description 9
- RNFNDJAIBTYOQL-UHFFFAOYSA-N Chloral hydrate Chemical compound OC(O)C(Cl)(Cl)Cl RNFNDJAIBTYOQL-UHFFFAOYSA-N 0.000 claims description 9
- HFFLGKNGCAIQMO-UHFFFAOYSA-N Chloral Chemical compound ClC(Cl)(Cl)C=O HFFLGKNGCAIQMO-UHFFFAOYSA-N 0.000 claims description 8
- 230000000202 analgesic Effects 0.000 claims description 6
- 125000004432 carbon atoms Chemical group C* 0.000 claims description 6
- 230000001624 sedative Effects 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 4
- 239000000155 melt Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 5
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 239000000376 reactant Substances 0.000 claims 1
- 229920001098 polystyrene-block-poly(ethylene/propylene) Polymers 0.000 description 34
- YXFVVABEGXRONW-UHFFFAOYSA-N toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- SKZKKFZAGNVIMN-UHFFFAOYSA-N Salicilamide Chemical compound NC(=O)C1=CC=CC=C1O SKZKKFZAGNVIMN-UHFFFAOYSA-N 0.000 description 6
- 229960000581 salicylamide Drugs 0.000 description 6
- -1 alkyl radical Chemical group 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- YGSDEFSMJLZEOE-UHFFFAOYSA-N Salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 4
- 241000700159 Rattus Species 0.000 description 3
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical group [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 description 2
- RMRFFCXPLWYOOY-UHFFFAOYSA-N Allyl radical Chemical compound [CH2]C=C RMRFFCXPLWYOOY-UHFFFAOYSA-N 0.000 description 2
- RGIHCEXVFLIBON-UHFFFAOYSA-N C(C)C1(C(C(=O)N)C=CC=C1)O Chemical compound C(C)C1(C(C(=O)N)C=CC=C1)O RGIHCEXVFLIBON-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- 239000000932 sedative agent Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 229940035676 ANALGESICS Drugs 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- QXLPXWSKPNOQLE-UHFFFAOYSA-N Methylpentynol Chemical compound CCC(C)(O)C#C QXLPXWSKPNOQLE-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000005712 crystallization Effects 0.000 description 1
- 229940079593 drugs Drugs 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000000147 hypnotic Effects 0.000 description 1
- 230000003522 irritant Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000000056 organs Anatomy 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 150000003254 radicals Chemical group 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 231100000486 side effect Toxicity 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002195 synergetic Effects 0.000 description 1
- 230000002588 toxic Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE571821A true BE571821A (el) |
Family
ID=189870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE571821D BE571821A (el) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE571821A (el) |
-
0
- BE BE571821D patent/BE571821A/fr unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CH641798A5 (fr) | Derives de dibenzothiepinne et leur procede de synthese. | |
| CA1060039A (fr) | Derives des acides 3-benzoyl-phenylalcanoiques et-alcenoiques | |
| CH464172A (fr) | Procédé de préparation d'acides carboxyliques -substitués | |
| BE571821A (el) | ||
| CH624089A5 (el) | ||
| BE563113A (el) | ||
| FR2519977A1 (fr) | Procede de preparation de chloroacetanilides substitues | |
| BE558138A (el) | ||
| CA1211442A (fr) | Procede pour la preparation de p-acylaminophenol | |
| BE735553A (en) | Diuretic and analgetic 9-fluoroenylsulphone - derivs | |
| BE642315A (el) | ||
| BE533436A (el) | ||
| BE574132A (el) | ||
| BE649734A (el) | ||
| BE667262A (el) | ||
| BE659237A (el) | ||
| BE550919A (el) | ||
| BE510970A (el) | ||
| BE517657A (el) | ||
| BE504409A (el) | ||
| BE517991A (el) | ||
| CH495936A (fr) | Procédé de préparation de nouveaux composés aryloxy | |
| BE529377A (el) | ||
| BE541651A (el) | ||
| BE517656A (el) |