BE536545A - - Google Patents
Info
- Publication number
- BE536545A BE536545A BE536545DA BE536545A BE 536545 A BE536545 A BE 536545A BE 536545D A BE536545D A BE 536545DA BE 536545 A BE536545 A BE 536545A
- Authority
- BE
- Belgium
- Prior art keywords
- cyclohexylisopropylmethylamine
- hydrochloride
- ephedrine
- base
- hydrogen
- Prior art date
Links
- 238000000034 method Methods 0.000 claims description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 6
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 claims 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- BALXUFOVQVENIU-GNAZCLTHSA-N Ephedrine hydrochloride Chemical compound Cl.CN[C@@H](C)[C@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-GNAZCLTHSA-N 0.000 claims 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 4
- 239000003054 catalyst Substances 0.000 claims 4
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- 229960000583 acetic acid Drugs 0.000 claims 3
- 238000009903 catalytic hydrogenation reaction Methods 0.000 claims 3
- 229960002179 ephedrine Drugs 0.000 claims 3
- 239000012362 glacial acetic acid Substances 0.000 claims 3
- BVTMNDSCUKZTCE-UHFFFAOYSA-N n-methyl-n-propan-2-ylcyclohexanamine Chemical compound CC(C)N(C)C1CCCCC1 BVTMNDSCUKZTCE-UHFFFAOYSA-N 0.000 claims 3
- MUMZUERVLWJKNR-UHFFFAOYSA-N oxoplatinum Chemical compound [Pt]=O MUMZUERVLWJKNR-UHFFFAOYSA-N 0.000 claims 3
- 229910003446 platinum oxide Inorganic materials 0.000 claims 3
- BALXUFOVQVENIU-KXNXZCPBSA-N pseudoephedrine hydrochloride Chemical compound [H+].[Cl-].CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-KXNXZCPBSA-N 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- WLEGHNSHAIHZPS-UHFFFAOYSA-N 1-cyclohexyl-n-methylpropan-2-amine;hydrochloride Chemical compound Cl.CNC(C)CC1CCCCC1 WLEGHNSHAIHZPS-UHFFFAOYSA-N 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 229960002534 ephedrine hydrochloride Drugs 0.000 claims 2
- 238000005984 hydrogenation reaction Methods 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 230000001476 alcoholic effect Effects 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 150000004982 aromatic amines Chemical class 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 238000004508 fractional distillation Methods 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 229960003447 pseudoephedrine hydrochloride Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 235000011121 sodium hydroxide Nutrition 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE536545A true BE536545A (enrdf_load_stackoverflow) |
Family
ID=167197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE536545D BE536545A (enrdf_load_stackoverflow) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE536545A (enrdf_load_stackoverflow) |
-
0
- BE BE536545D patent/BE536545A/fr unknown
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