BE536229A - - Google Patents

Info

Publication number

BE536229A

BE536229A BE536229DA BE536229A BE 536229 A BE536229 A BE 536229A BE 536229D A BE536229D A BE 536229DA BE 536229 A BE536229 A BE 536229A

Authority

BE

Belgium

Prior art keywords

sep

xanthocillin

product

compounds

tyrothricin

Prior art date

Links

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• 239000000047 product Substances 0.000 claims description 24
• YBMVKDUTYAGKEW-WHYMJUELSA-N 4-[(1Z,3Z)-4-(4-hydroxyphenyl)-2,3-diisocyanobuta-1,3-dienyl]phenol Chemical compound C1=CC(O)=CC=C1\C=C(/[N+]#[C-])\C(\[N+]#[C-])=C\C1=CC=C(O)C=C1 YBMVKDUTYAGKEW-WHYMJUELSA-N 0.000 claims description 14
• GSXRBRIWJGAPDU-BBVRJQLQSA-N Tyrothricin Chemical compound C([C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCCN)C(=O)N[C@H](C(N[C@H](CC=2C=CC=CC=2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N1)=O)CC(C)C)C(C)C)C1=CC=C(O)C=C1 GSXRBRIWJGAPDU-BBVRJQLQSA-N 0.000 claims description 11
• 108010021006 Tyrothricin Proteins 0.000 claims description 10
• 229960003281 tyrothricin Drugs 0.000 claims description 10
• 230000000249 desinfective Effects 0.000 claims description 9
• 239000000645 desinfectant Substances 0.000 claims description 8
• 239000002904 solvent Substances 0.000 claims description 5
• 238000006243 chemical reaction Methods 0.000 claims description 3
• 239000007795 chemical reaction product Substances 0.000 claims description 3
• 239000011149 active material Substances 0.000 claims 1
• 229920001098 polystyrene-block-poly(ethylene/propylene) Polymers 0.000 description 68
• 239000000243 solution Substances 0.000 description 17
• 150000001875 compounds Chemical class 0.000 description 13
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
• 235000019441 ethanol Nutrition 0.000 description 7
• 230000000844 anti-bacterial Effects 0.000 description 4
• 150000003839 salts Chemical class 0.000 description 4
• 239000000126 substance Substances 0.000 description 4
• 239000002253 acid Substances 0.000 description 3
• 230000015572 biosynthetic process Effects 0.000 description 3
• 230000000694 effects Effects 0.000 description 3
• 238000001914 filtration Methods 0.000 description 3
• 238000005755 formation reaction Methods 0.000 description 3
• 239000012535 impurity Substances 0.000 description 3
• 239000011780 sodium chloride Substances 0.000 description 3
• 241000894006 Bacteria Species 0.000 description 2
• WQZGKKKJIJFFOK-GASJEMHNSA-N D-Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
• 108010026389 Gramicidin Proteins 0.000 description 2
• 229960004905 Gramicidin Drugs 0.000 description 2
• IUAYMJGZBVDSGL-XNNAEKOYSA-N Gramicidin S Chemical compound C([C@@H]1C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CCCN)C(=O)N[C@H](C(N[C@H](CC=2C=CC=CC=2)C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(C)C)C(=O)N1)C(C)C)=O)CC(C)C)C(C)C)C1=CC=CC=C1 IUAYMJGZBVDSGL-XNNAEKOYSA-N 0.000 description 2
• VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
• 241000588769 Proteus <enterobacteria> Species 0.000 description 2
• 241000295644 Staphylococcaceae Species 0.000 description 2
• CSCPPACGZOOCGX-UHFFFAOYSA-N acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
• 230000003385 bacteriostatic Effects 0.000 description 2
• 239000000470 constituent Substances 0.000 description 2
• 238000001816 cooling Methods 0.000 description 2
• 239000008103 glucose Substances 0.000 description 2
• 239000002674 ointment Substances 0.000 description 2
• 239000000843 powder Substances 0.000 description 2
• 239000000725 suspension Substances 0.000 description 2
• RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
• 210000004400 Mucous Membrane Anatomy 0.000 description 1
• 240000003670 Sesamum indicum Species 0.000 description 1
• 210000003491 Skin Anatomy 0.000 description 1
• 238000010521 absorption reaction Methods 0.000 description 1
• 150000007513 acids Chemical class 0.000 description 1
• 239000000654 additive Substances 0.000 description 1
• 125000003277 amino group Chemical group 0.000 description 1
• 229940077747 antacids containing calcium compounds Drugs 0.000 description 1
• 229940077744 antacids containing magnesium compounds Drugs 0.000 description 1
• 239000007864 aqueous solution Substances 0.000 description 1
• 230000000721 bacterilogical Effects 0.000 description 1
• 150000001674 calcium compounds Chemical class 0.000 description 1
• 229940043430 calcium compounds Drugs 0.000 description 1
• 159000000007 calcium salts Chemical class 0.000 description 1
• 239000000969 carrier Substances 0.000 description 1
• 230000001627 detrimental Effects 0.000 description 1
• 238000007865 diluting Methods 0.000 description 1
• 239000012153 distilled water Substances 0.000 description 1
• 238000001035 drying Methods 0.000 description 1
• 150000002148 esters Chemical class 0.000 description 1
• 238000001704 evaporation Methods 0.000 description 1
• 239000000706 filtrate Substances 0.000 description 1
• 239000008233 hard water Substances 0.000 description 1
• 235000015110 jellies Nutrition 0.000 description 1
• 150000002681 magnesium compounds Chemical class 0.000 description 1
• 159000000003 magnesium salts Chemical class 0.000 description 1
• 238000000034 method Methods 0.000 description 1
• 244000005700 microbiome Species 0.000 description 1
• 239000003960 organic solvent Substances 0.000 description 1
• 235000010603 pastilles Nutrition 0.000 description 1
• 230000001717 pathogenic Effects 0.000 description 1
• 244000052769 pathogens Species 0.000 description 1
• 229920001184 polypeptide Polymers 0.000 description 1
• 238000002360 preparation method Methods 0.000 description 1
• 238000005057 refrigeration Methods 0.000 description 1
• 230000000717 retained Effects 0.000 description 1
• 238000001228 spectrum Methods 0.000 description 1
• 239000008399 tap water Substances 0.000 description 1
• 235000020679 tap water Nutrition 0.000 description 1