BE2017C059I2 - - Google Patents
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- BE2017C059I2 BE2017C059I2 BE2017C059C BE2017C059C BE2017C059I2 BE 2017C059 I2 BE2017C059 I2 BE 2017C059I2 BE 2017C059 C BE2017C059 C BE 2017C059C BE 2017C059 C BE2017C059 C BE 2017C059C BE 2017C059 I2 BE2017C059 I2 BE 2017C059I2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
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- A—HUMAN NECESSITIES
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
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- A—HUMAN NECESSITIES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A—HUMAN NECESSITIES
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A—HUMAN NECESSITIES
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
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- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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AR087433A1 (es) * | 2011-08-08 | 2014-03-26 | Merck Sharp & Dohme | Analogos de insulina n-glicosilados |
EP2956003A2 (en) | 2013-02-13 | 2015-12-23 | Laboratoire Français du Fractionnement et des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
MX2015010428A (es) * | 2013-02-13 | 2016-04-13 | Lab Francais Du Fractionnement | Anticuerpos anti-her2 altamente galactosilados y sus usos. |
JP2016508515A (ja) | 2013-02-13 | 2016-03-22 | ラボラトワール フランセ デュ フラクショヌマン エ デ ビオテクノロジーLaboratoire Francais du Fractionnement et des Biotechnologies | 高ガラクトシル化抗TNF−α抗体およびその使用 |
SG10201809779RA (en) | 2013-03-11 | 2018-12-28 | Genzyme Corp | Site-specific antibody-drug conjugation through glycoengineering |
DK2991683T3 (da) | 2013-05-02 | 2019-11-04 | Glykos Finland Oy | Konjugater af et glykoprotein eller en glykan med en toksisk ladning |
DK3129067T5 (da) | 2014-03-19 | 2024-10-14 | Genzyme Corp | Sitespecifik glycomodificering af målsøgningsdele |
AU2015243512B2 (en) | 2014-04-08 | 2020-06-04 | University Of Georgia Research Foundation Inc. | Site-specific antibody-drug glycoconjugates and methods |
CN105505884B (zh) * | 2016-01-26 | 2017-10-03 | 郑州师范学院 | 进行抗体表达和组装的重组系统及应用 |
EP4285934A1 (en) | 2022-05-30 | 2023-12-06 | CER Groupe | Modified trimannose-oligosacharides, bisected n-glycans comprising said trimannose core and method for obtaining them |
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2002
- 2002-10-09 DK DK10012536.8T patent/DK2279753T3/en active
- 2002-10-09 EP EP10012798.4A patent/EP2305314B1/en not_active Expired - Lifetime
- 2002-10-09 EP EP20100012793 patent/EP2305311A3/en not_active Withdrawn
- 2002-10-09 CN CN201510483413.4A patent/CN105131104B/zh not_active Expired - Lifetime
- 2002-10-09 EP EP10185505A patent/EP2292273A3/en not_active Withdrawn
- 2002-10-09 DK DK10012939.4T patent/DK2279755T3/da active
- 2002-10-09 EP EP10012797.6A patent/EP2305313B1/en not_active Expired - Lifetime
- 2002-10-09 EP EP10012796.8A patent/EP2298354B1/en not_active Expired - Lifetime
- 2002-10-09 EP EP10012794.3A patent/EP2305312B1/en not_active Expired - Lifetime
- 2002-10-09 ZA ZA200700168A patent/ZA200700168B/xx unknown
- 2002-10-09 EP EP10184886.9A patent/EP2322229B1/en not_active Expired - Lifetime
-
2004
- 2004-04-05 ZA ZA200402673A patent/ZA200402673B/en unknown
-
2017
- 2017-11-28 BE BE2017C059C patent/BE2017C059I2/nl unknown
- 2017-11-30 FR FR17C1053C patent/FR17C1053I2/fr active Active
Also Published As
Publication number | Publication date |
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EP2298354A3 (en) | 2011-06-08 |
EP2305313A2 (en) | 2011-04-06 |
DK2279753T3 (en) | 2015-11-23 |
EP2298354A2 (en) | 2011-03-23 |
CN105131104A (zh) | 2015-12-09 |
EP2305314A2 (en) | 2011-04-06 |
FR17C1053I1 (is) | 2018-01-12 |
EP2305313A3 (en) | 2011-06-08 |
CN105131104B (zh) | 2018-11-16 |
EP2305314B1 (en) | 2015-12-23 |
ZA200402673B (en) | 2007-03-28 |
EP2305311A2 (en) | 2011-04-06 |
EP2322229B1 (en) | 2016-12-21 |
EP2322229A2 (en) | 2011-05-18 |
FR17C1053I2 (fr) | 2019-01-11 |
EP2298354B1 (en) | 2014-03-19 |
EP2305314A3 (en) | 2011-09-14 |
EP2305313B1 (en) | 2014-03-26 |
EP2292273A2 (en) | 2011-03-09 |
EP2305311A3 (en) | 2011-07-20 |
DK2279755T3 (da) | 2014-05-26 |
EP2305312B1 (en) | 2015-03-04 |
EP2305312A3 (en) | 2011-06-15 |
EP2292273A3 (en) | 2011-11-23 |
EP2322229A3 (en) | 2012-03-07 |
ZA200700168B (en) | 2010-02-24 |
EP2305312A2 (en) | 2011-04-06 |