BE1016292A3 - Verbinding en gebruik bij behandeling. - Google Patents
Verbinding en gebruik bij behandeling. Download PDFInfo
- Publication number
- BE1016292A3 BE1016292A3 BE2004/0472A BE200400472A BE1016292A3 BE 1016292 A3 BE1016292 A3 BE 1016292A3 BE 2004/0472 A BE2004/0472 A BE 2004/0472A BE 200400472 A BE200400472 A BE 200400472A BE 1016292 A3 BE1016292 A3 BE 1016292A3
- Authority
- BE
- Belgium
- Prior art keywords
- treatment
- connection
- pharmaceutically acceptable
- epicholecalciferol
- bishomo
- Prior art date
Links
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 2
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 2
- LRLWXBHFPGSUOX-GJQYOBCGSA-N (1r,3z,5s)-3-[(2e)-2-[(3as,7as)-1-[(e,2s)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3h-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol Chemical compound C1(/[C@@H]2CC=C([C@]2(CCC1)C)[C@@H](C)C/C=C/C(O)(CC)CC)=C\C=C1\C[C@@H](O)C[C@H](F)C1=C LRLWXBHFPGSUOX-GJQYOBCGSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0322395A GB0322395D0 (en) | 2003-09-24 | 2003-09-24 | Methods for treating bladder dysfunction and related compounds and compositions |
| GB0325598A GB2407499B (en) | 2003-11-03 | 2003-11-03 | Vitamin D3 analogue for use in the treatment of BPH |
| GB0416876A GB0416876D0 (en) | 2004-07-29 | 2004-07-29 | Compound and use in treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE1016292A3 true BE1016292A3 (nl) | 2006-07-04 |
Family
ID=34229055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2004/0472A BE1016292A3 (nl) | 2003-09-24 | 2004-09-24 | Verbinding en gebruik bij behandeling. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1673096A1 (https=) |
| JP (2) | JP2007506699A (https=) |
| CN (1) | CN100488511C (https=) |
| BE (1) | BE1016292A3 (https=) |
| BR (1) | BRPI0404050A (https=) |
| CH (1) | CH698144B1 (https=) |
| EA (1) | EA010240B1 (https=) |
| FR (1) | FR2859910B1 (https=) |
| NL (1) | NL1027109C2 (https=) |
| NZ (1) | NZ535531A (https=) |
| WO (1) | WO2005027923A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090227651A1 (en) * | 2004-10-05 | 2009-09-10 | Kissei Pharmaceutical Co., Ltd. | Preventive and/or therapeutic agent for urine collection disorder accompanying lower urinary tract obstruction |
| PL1806136T3 (pl) * | 2004-10-06 | 2012-04-30 | Kissei Pharmaceutical | Kompozycja medyczna do zapobiegania przejściu na leczenie operacyjne łagodnego rozrostu gruczołu krokowego |
| US20100009949A1 (en) * | 2006-03-24 | 2010-01-14 | Bioxell S.P.A. | Novel method |
| US8221803B1 (en) | 2007-06-25 | 2012-07-17 | OncoNatural Solutions, Inc. | Composition for prostate health |
| US20120164240A1 (en) | 2010-12-22 | 2012-06-28 | Audino David Lawrence | Enriched a. blitoides compositions and uses thereof |
| US20170049834A1 (en) * | 2015-08-18 | 2017-02-23 | Golden Biotechnology Corporation | Benign prostatic hyperplasia add-on therapy |
| FR3063906B1 (fr) * | 2017-03-20 | 2025-12-12 | Pf Medicament | Utilisation de l'oleoresine de copaifera dans les pathologies de la prostate |
| CN120960385A (zh) * | 2025-08-01 | 2025-11-18 | 上海交通大学医学院附属第九人民医院 | 5α–还原酶降解分子及其制备方法和应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0808833A2 (en) * | 1996-05-23 | 1997-11-26 | F. Hoffmann-La Roche Ag | Vitamin D3 analogs |
| WO1998029123A1 (en) * | 1996-12-30 | 1998-07-09 | Bone Care International, Inc. | Method of treating prostatic diseases using active vitamin d analogues |
| WO2003034961A1 (en) * | 2001-10-23 | 2003-05-01 | Euro-Celtique, S.A. | Terazosin transdermal device and methods |
| WO2003047595A1 (en) * | 2001-12-03 | 2003-06-12 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin d compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW403735B (en) * | 1995-11-22 | 2000-09-01 | Hoffmann La Roche | 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol |
| CA2289209C (en) * | 1997-05-16 | 2006-07-25 | Women & Infants Hospital | Cyclic ether vitamin d3 compounds, 1.alpha. (oh) 3-epi-vitamin d3 compounds and uses thereof |
| US5872113A (en) * | 1997-05-16 | 1999-02-16 | Syntex (U.S.A.) Inc. | Fluorinated vitamin D3 analogs |
| US6255501B1 (en) * | 1999-04-26 | 2001-07-03 | Hoffman-La Roche Inc. | Process for preparing antiosteoporotic agents |
-
2004
- 2004-09-22 CH CH01553/04A patent/CH698144B1/fr not_active IP Right Cessation
- 2004-09-22 BR BR0404050-3A patent/BRPI0404050A/pt not_active IP Right Cessation
- 2004-09-23 EA EA200401100A patent/EA010240B1/ru not_active IP Right Cessation
- 2004-09-23 NZ NZ535531A patent/NZ535531A/xx unknown
- 2004-09-23 FR FR0410073A patent/FR2859910B1/fr not_active Expired - Fee Related
- 2004-09-24 WO PCT/EP2004/010760 patent/WO2005027923A1/en not_active Ceased
- 2004-09-24 NL NL1027109A patent/NL1027109C2/nl not_active IP Right Cessation
- 2004-09-24 JP JP2006527365A patent/JP2007506699A/ja not_active Abandoned
- 2004-09-24 EP EP04765598A patent/EP1673096A1/en not_active Withdrawn
- 2004-09-24 CN CNB2004100800817A patent/CN100488511C/zh not_active Expired - Fee Related
- 2004-09-24 BE BE2004/0472A patent/BE1016292A3/nl not_active IP Right Cessation
-
2008
- 2008-08-18 JP JP2008209429A patent/JP2009035559A/ja not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0808833A2 (en) * | 1996-05-23 | 1997-11-26 | F. Hoffmann-La Roche Ag | Vitamin D3 analogs |
| WO1998029123A1 (en) * | 1996-12-30 | 1998-07-09 | Bone Care International, Inc. | Method of treating prostatic diseases using active vitamin d analogues |
| WO2003034961A1 (en) * | 2001-10-23 | 2003-05-01 | Euro-Celtique, S.A. | Terazosin transdermal device and methods |
| WO2003047595A1 (en) * | 2001-12-03 | 2003-06-12 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin d compounds |
Non-Patent Citations (5)
| Title |
|---|
| ANON: "BioXell commences phase II trial of BXL - 628", DRUG NEWS & PERSPECTIVES, (MAR 2003) VOL. 16, NO. 2, PP. 122-122. PUBLISHER: PROUS SCIENCE, SA, PO BOX 540, PROVENZA 388, 08025 BARCELONA, SPAIN. ISSN: 0214-0934., March 2003 (2003-03-01), XP001205124 * |
| BRANDL MICHAEL ET AL: "Chemical reactivity of Ro-26-9228, 1alpha-fluoro-25-hydroxy-16,23E-di ene-26,27-bishomo-20-epi-cholecalciferol in aqueous solution.", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 92, no. 10, October 2003 (2003-10-01), pages 1981 - 1989, XP002315528, ISSN: 0022-3549 * |
| CRESCIOLI C ET AL: "Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia", EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol. 150, no. 4, April 2004 (2004-04-01), pages 591 - 603, XP009043025, ISSN: 0804-4643 * |
| http://www3.interscience.wiley.com/cgi-bin/abstract/104550629/ABSTRACT, Published Online 30 Jul 2003 * |
| MEALY N E: "BXL-628", DRUGS OF THE FUTURE 2004 SPAIN, vol. 29, no. 6, 2004, pages 629, XP009043214, ISSN: 0377-8282 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EA010240B1 (ru) | 2008-06-30 |
| EP1673096A1 (en) | 2006-06-28 |
| NZ535531A (en) | 2006-03-31 |
| NL1027109A1 (nl) | 2005-03-29 |
| BRPI0404050A (pt) | 2005-06-14 |
| WO2005027923A1 (en) | 2005-03-31 |
| CN100488511C (zh) | 2009-05-20 |
| NL1027109C2 (nl) | 2005-05-03 |
| CN1615891A (zh) | 2005-05-18 |
| FR2859910B1 (fr) | 2006-04-28 |
| JP2007506699A (ja) | 2007-03-22 |
| EA200401100A1 (ru) | 2005-04-28 |
| JP2009035559A (ja) | 2009-02-19 |
| HK1085373A1 (zh) | 2006-08-25 |
| CH698144B1 (fr) | 2009-05-29 |
| FR2859910A1 (fr) | 2005-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Effective date: 20100930 |