BE1001550A5 - Utilisation d'amines aromatiques et heterocycliques comme medicaments et produits agrochimiques. - Google Patents

Utilisation d'amines aromatiques et heterocycliques comme medicaments et produits agrochimiques. Download PDF

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Publication number
BE1001550A5
BE1001550A5 BE8700051A BE8700051A BE1001550A5 BE 1001550 A5 BE1001550 A5 BE 1001550A5 BE 8700051 A BE8700051 A BE 8700051A BE 8700051 A BE8700051 A BE 8700051A BE 1001550 A5 BE1001550 A5 BE 1001550A5
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group
agrochemicals
medicines
aromatic
heterocyclic amines
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BE8700051A
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English (en)
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Sandoz Sa
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/31—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by at least three rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Composés (fig. I) où R1 et R2 forment un groupe (fig. IIg) ou bien R2 signifie H, ou un alkyle et R1 un autre groupe (fig. IIa à IIf) R4 et R5 représentent H ou un groupe alkyle, R3 signifie H, alkyle, cycloalkyle ou halogénoalkyle et R6 un autre groupe (fig.IIIa à IIIe) ou bien R1 représente un groupe IIa à IIf comme ci-dessus et R2 et R3 forment un groupe (CH2)u et les symboles R7 à R12, X, p, s, u, v, w, et Z ont des significations variées.
BE8700051A 1986-01-29 1987-01-27 Utilisation d'amines aromatiques et heterocycliques comme medicaments et produits agrochimiques. BE1001550A5 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3602579 1986-01-29
DE3609123 1986-03-19
DE3617635 1986-05-26
DE3617637 1986-05-26

Publications (1)

Publication Number Publication Date
BE1001550A5 true BE1001550A5 (fr) 1989-12-05

Family

ID=27433512

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700051A BE1001550A5 (fr) 1986-01-29 1987-01-27 Utilisation d'amines aromatiques et heterocycliques comme medicaments et produits agrochimiques.

Country Status (24)

Country Link
US (2) US4939148A (fr)
KR (1) KR920010574B1 (fr)
AT (1) AT398761B (fr)
AU (1) AU607694B2 (fr)
BE (1) BE1001550A5 (fr)
CA (1) CA1329619C (fr)
CH (1) CH672875A5 (fr)
CY (1) CY1726A (fr)
DK (1) DK46387A (fr)
ES (1) ES2004079A6 (fr)
FI (1) FI89707C (fr)
FR (1) FR2597475B1 (fr)
GB (1) GB2185980B (fr)
GR (1) GR870127B (fr)
HK (1) HK110193A (fr)
HU (1) HU211997B (fr)
IE (1) IE59490B1 (fr)
IL (1) IL81410A (fr)
LU (1) LU86745A1 (fr)
NL (1) NL8700083A (fr)
NZ (1) NZ219069A (fr)
PT (1) PT84199B (fr)
SE (1) SE8700328L (fr)
SG (1) SG63593G (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334628A (en) * 1984-06-09 1994-08-02 Kaken Pharmaceutical Co., Ltd. Amine derivatives, processes for preparing the same and fungicides containing the same
JPS6145A (ja) * 1984-06-09 1986-01-06 Kaken Pharmaceut Co Ltd Ｎ‐（４‐ｔｅｒｔ‐ブチルベンジル）‐Ｎ‐メチル‐１‐ナフチルメチルアミンおよびそれを有効成分とする抗真菌剤
JP2581707B2 (ja) * 1987-10-02 1997-02-12 科研製薬株式会社 抗真菌剤組成物
NZ227042A (en) * 1987-11-27 1991-05-28 Banyu Pharma Co Ltd Substituted alkylamine derivatives and pharmaceutical compositions
US5234946A (en) * 1987-11-27 1993-08-10 Banyu Pharmaceutical Co., Ltd. Substituted alkylamine derivatives
GT198900008A (es) * 1988-01-29 1990-07-17 Derivados de quinolina, quinazolina y cinolina.
IL89029A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them
DE3838631A1 (de) * 1988-11-15 1990-05-23 Basf Ag Neue 2-aminodekalin-derivate und deren verwendung
CA2044533A1 (fr) * 1990-06-29 1991-12-30 Philippe Guerry Derives aminoalkylbiphenyliques substitues
US5239084A (en) * 1990-06-29 1993-08-24 Hoffmann-La Roche Inc. Substituted aminoalkyl biphenyl compounds
FR2664592B1 (fr) * 1990-07-10 1994-09-02 Adir Nouveaux derives de la piperidine, de la tetrahydropyridine et de la pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US6117884A (en) * 1997-07-31 2000-09-12 Daeuble; John 4-substituted quinoline derivatives having fungicidal activity
CN108047057B (zh) * 2017-12-28 2020-06-02 山东铂源药业有限公司 一种布替萘芬的合成方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1109924A (en) * 1965-11-29 1968-04-18 Roche Products Ltd Novel substituted diphenylalkyl amines and a process for the manufacture thereof
DE2048147A1 (de) * 1969-10-01 1971-04-08 E R Squibb & Sons Ine , New York, NY (VStA) Acenaphthylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US3862330A (en) * 1971-03-18 1975-01-21 Robert P Johnson N-(c{hd 8{b -c{hd 12 {b alkyl) diaralkylamines used to combat plant fungi
EP0024587A1 (fr) * 1979-08-22 1981-03-11 Sandoz Ag Propénylamines, procédés pour leur préparation, compositions pharmaceutiques les contenant et leur utilisation comme médicaments
EP0164697A2 (fr) * 1984-06-09 1985-12-18 Kaken Pharmaceutical Co., Ltd. Dérivés d'amines, procédé pour leur préparation et fongicides les contenant
JPS61282348A (ja) * 1985-06-08 1986-12-12 Kaken Pharmaceut Co Ltd アミン化合物およびそれを有効成分とする抗真菌剤
EP0221781A2 (fr) * 1985-11-01 1987-05-13 MITSUI TOATSU CHEMICALS, Inc. Dérivés de benzylamine, leur procédé de préparation et leur utilisation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598839A (en) * 1969-06-30 1971-08-10 Parke Davis & Co Phenylbenzothiophene compounds
US4552960A (en) * 1983-06-20 1985-11-12 Eli Lilly And Company Fungicidal amines
US4761424A (en) * 1985-10-01 1988-08-02 Warner-Lambert Company Enolamides, pharmaceutical compositions and methods for treating inflammation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1109924A (en) * 1965-11-29 1968-04-18 Roche Products Ltd Novel substituted diphenylalkyl amines and a process for the manufacture thereof
DE2048147A1 (de) * 1969-10-01 1971-04-08 E R Squibb & Sons Ine , New York, NY (VStA) Acenaphthylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US3862330A (en) * 1971-03-18 1975-01-21 Robert P Johnson N-(c{hd 8{b -c{hd 12 {b alkyl) diaralkylamines used to combat plant fungi
EP0024587A1 (fr) * 1979-08-22 1981-03-11 Sandoz Ag Propénylamines, procédés pour leur préparation, compositions pharmaceutiques les contenant et leur utilisation comme médicaments
EP0164697A2 (fr) * 1984-06-09 1985-12-18 Kaken Pharmaceutical Co., Ltd. Dérivés d'amines, procédé pour leur préparation et fongicides les contenant
JPS61282348A (ja) * 1985-06-08 1986-12-12 Kaken Pharmaceut Co Ltd アミン化合物およびそれを有効成分とする抗真菌剤
EP0221781A2 (fr) * 1985-11-01 1987-05-13 MITSUI TOATSU CHEMICALS, Inc. Dérivés de benzylamine, leur procédé de préparation et leur utilisation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 106, 11 mai 1987, page 651, résumé no. 156080u, Columbus, Ohio, US; & JP-A-61 282 348 (KAKEN PHARMACEUTICAL CO. LTD) 12-12-1986 *

Also Published As

Publication number Publication date
SE8700328D0 (sv) 1987-01-28
FR2597475B1 (fr) 1991-09-20
NL8700083A (nl) 1987-08-17
PT84199A (en) 1987-02-01
HU211997B (en) 1996-01-29
GB2185980A (en) 1987-08-05
GR870127B (en) 1987-05-28
ATA15987A (de) 1994-06-15
KR920010574B1 (ko) 1992-12-07
CY1726A (en) 1994-05-06
HUT46652A (en) 1988-11-28
FI870342A (fi) 1987-07-30
GB8701646D0 (en) 1987-03-04
DK46387A (da) 1987-07-30
US5112851A (en) 1992-05-12
CH672875A5 (fr) 1990-01-15
IL81410A (en) 1992-01-15
IE59490B1 (en) 1994-03-09
FI89707B (fi) 1993-07-30
IE870207L (en) 1987-07-29
PT84199B (pt) 1989-09-14
FR2597475A1 (fr) 1987-10-23
LU86745A1 (fr) 1987-09-03
GB2185980B (en) 1990-08-15
AU607694B2 (en) 1991-03-14
IL81410A0 (en) 1987-08-31
HK110193A (en) 1993-10-29
FI870342A0 (fi) 1987-01-27
SG63593G (en) 1993-08-06
ES2004079A6 (es) 1988-12-01
AT398761B (de) 1995-01-25
KR870007099A (ko) 1987-08-14
US4939148A (en) 1990-07-03
DK46387D0 (da) 1987-01-28
FI89707C (fi) 1993-11-10
AU6811987A (en) 1987-07-30
NZ219069A (en) 1990-11-27
CA1329619C (fr) 1994-05-17
SE8700328L (sv) 1987-07-30

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RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19970131