AU9205998A - A method of treating cancer - Google Patents

A method of treating cancer Download PDF

Info

Publication number
AU9205998A
AU9205998A AU92059/98A AU9205998A AU9205998A AU 9205998 A AU9205998 A AU 9205998A AU 92059/98 A AU92059/98 A AU 92059/98A AU 9205998 A AU9205998 A AU 9205998A AU 9205998 A AU9205998 A AU 9205998A
Authority
AU
Australia
Prior art keywords
protein
farnesyl
geranylgeranyl
protein transferase
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU92059/98A
Other languages
English (en)
Inventor
Anne L. Burkhardt
Carolyn A. Buser-Doepner
Pearl S. Huang
Kenneth S Koblan
Nancy E Kohl
Robert B Lobell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9807361.2A external-priority patent/GB9807361D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU9205998A publication Critical patent/AU9205998A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU92059/98A 1997-08-27 1998-08-26 A method of treating cancer Abandoned AU9205998A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5722897P 1997-08-27 1997-08-27
US60057228 1997-08-27
GB9807361 1998-04-06
GBGB9807361.2A GB9807361D0 (en) 1998-04-06 1998-04-06 A method of treating cancer
PCT/US1998/017698 WO1999010524A1 (fr) 1997-08-27 1998-08-26 Procede pour le traitement du cancer

Publications (1)

Publication Number Publication Date
AU9205998A true AU9205998A (en) 1999-03-16

Family

ID=26313438

Family Applications (1)

Application Number Title Priority Date Filing Date
AU92059/98A Abandoned AU9205998A (en) 1997-08-27 1998-08-26 A method of treating cancer

Country Status (5)

Country Link
EP (1) EP1019530A1 (fr)
JP (1) JP2001514011A (fr)
AU (1) AU9205998A (fr)
CA (1) CA2301857A1 (fr)
WO (1) WO1999010524A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849599B2 (en) 2000-03-08 2005-02-01 Rhode Island Hospital Combination drug therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185248A (en) * 1990-05-08 1993-02-09 E. R. Squibb & Sons, Inc. Farnesyl-protein transferase assay for identifying compounds that block neoplastic transformation

Also Published As

Publication number Publication date
WO1999010524A1 (fr) 1999-03-04
CA2301857A1 (fr) 1999-03-04
JP2001514011A (ja) 2001-09-11
EP1019530A1 (fr) 2000-07-19

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted