AU7964087A - Hydroxy indole derivatives - Google Patents

Hydroxy indole derivatives

Info

Publication number
AU7964087A
AU7964087A AU79640/87A AU7964087A AU7964087A AU 7964087 A AU7964087 A AU 7964087A AU 79640/87 A AU79640/87 A AU 79640/87A AU 7964087 A AU7964087 A AU 7964087A AU 7964087 A AU7964087 A AU 7964087A
Authority
AU
Australia
Prior art keywords
indole derivatives
hydroxy indole
hydroxy
derivatives
indole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU79640/87A
Other versions
AU594512B2 (en
Inventor
Rolf Bergmann
Henning Bottcher
Hans-Heinrich Hausberg
Christoph Seyfried
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/907,909 external-priority patent/US4711893A/en
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU7964087A publication Critical patent/AU7964087A/en
Application granted granted Critical
Publication of AU594512B2 publication Critical patent/AU594512B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
AU79640/87A 1986-09-16 1987-09-12 Hydroxy indole derivatives Ceased AU594512B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US907909 1986-09-16
US06/907,909 US4711893A (en) 1984-05-28 1986-09-16 Use of hydroxyindole derivatives in lowering blood pressure

Publications (2)

Publication Number Publication Date
AU7964087A true AU7964087A (en) 1988-04-07
AU594512B2 AU594512B2 (en) 1990-03-08

Family

ID=25424843

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79640/87A Ceased AU594512B2 (en) 1986-09-16 1987-09-12 Hydroxy indole derivatives

Country Status (6)

Country Link
EP (1) EP0281608B1 (en)
JP (1) JPH0822859B2 (en)
KR (1) KR950011409B1 (en)
AU (1) AU594512B2 (en)
SG (1) SG118592G (en)
WO (1) WO1988001998A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU622291B2 (en) * 1989-03-11 1992-04-02 Merck Patent Gesellschaft Mit Beschrankter Haftung (substituted (1,2,3,6-tetrahydropyrid-1-yl)alkyl or thio- alkyl)indoles

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4141268A1 (en) * 1991-12-14 1993-06-17 Merck Patent Gmbh PHARMACEUTICAL PREPARATION
TR200200971T2 (en) * 1998-09-29 2002-06-21 Fujisawa Pharmaceutical Co., Ltd. New salts of the pyridopyrazine compound and their crystals.
KR100496089B1 (en) * 2000-03-03 2005-06-17 화이자 인코포레이티드 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline mesylate and polymorphs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007399B1 (en) * 1978-06-24 1982-01-20 MERCK PATENT GmbH Indolylalkyl amines, pharmaceutical preparations containing them and process for their manufacture
DE2827874A1 (en) * 1978-06-24 1980-02-07 Merck Patent Gmbh N-Indolyl:alkyl-4-phenyl-piperidine derivs. - with CNS activity e.g. for treating Parkinson's disease or depression

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU622291B2 (en) * 1989-03-11 1992-04-02 Merck Patent Gesellschaft Mit Beschrankter Haftung (substituted (1,2,3,6-tetrahydropyrid-1-yl)alkyl or thio- alkyl)indoles

Also Published As

Publication number Publication date
JPH01501548A (en) 1989-06-01
JPH0822859B2 (en) 1996-03-06
WO1988001998A1 (en) 1988-03-24
KR950011409B1 (en) 1995-10-04
SG118592G (en) 1993-01-29
EP0281608B1 (en) 1990-07-11
EP0281608A1 (en) 1988-09-14
AU594512B2 (en) 1990-03-08
KR880701709A (en) 1988-11-04

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