AU781775B2 - Adenoviral vectors for treating disease - Google Patents

Adenoviral vectors for treating disease Download PDF

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Publication number
AU781775B2
AU781775B2 AU60578/00A AU6057800A AU781775B2 AU 781775 B2 AU781775 B2 AU 781775B2 AU 60578/00 A AU60578/00 A AU 60578/00A AU 6057800 A AU6057800 A AU 6057800A AU 781775 B2 AU781775 B2 AU 781775B2
Authority
AU
Australia
Prior art keywords
gene
region
adenoviral vector
onyx
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU60578/00A
Other languages
English (en)
Other versions
AU6057800A (en
Inventor
Lynda K. Hawkins
Terry Hermiston
Leisa Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Onyx Pharmaceuticals Inc
Original Assignee
Onyx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onyx Pharmaceuticals Inc filed Critical Onyx Pharmaceuticals Inc
Publication of AU6057800A publication Critical patent/AU6057800A/en
Application granted granted Critical
Publication of AU781775B2 publication Critical patent/AU781775B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU60578/00A 1999-07-02 2000-06-28 Adenoviral vectors for treating disease Ceased AU781775B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34760499A 1999-07-02 1999-07-02
US09/347604 1999-07-02
PCT/US2000/017856 WO2001002540A2 (fr) 1999-07-02 2000-06-28 Vecteurs adenoviraux de traitement de maladies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2005209653A Division AU2005209653B2 (en) 1999-07-02 2005-09-09 Adenoviral vectors for treating disease

Publications (2)

Publication Number Publication Date
AU6057800A AU6057800A (en) 2001-01-22
AU781775B2 true AU781775B2 (en) 2005-06-09

Family

ID=23364433

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60578/00A Ceased AU781775B2 (en) 1999-07-02 2000-06-28 Adenoviral vectors for treating disease

Country Status (6)

Country Link
EP (1) EP1218527A2 (fr)
JP (1) JP2003504316A (fr)
CN (1) CN1357050A (fr)
AU (1) AU781775B2 (fr)
CA (1) CA2373352A1 (fr)
WO (1) WO2001002540A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004536572A (ja) 2001-02-23 2004-12-09 セル・ジェネシス・インコーポレイテッド 新規ベクター構築物
WO2006110689A2 (fr) * 2005-04-07 2006-10-19 The Trustees Of The University Of Pennsylvania Procede d'augmentation de la fonction d'un vecteur aav
CN101979606A (zh) * 2010-11-01 2011-02-23 陕西师范大学 一种以腺病毒表达系统产生的人逆转录泡沫病毒载体
CN105274142B (zh) * 2014-06-25 2018-12-04 中国科学院广州生物医药与健康研究院 复制型重组人55型腺病毒载体及其制备方法和应用
CN104946602A (zh) * 2015-06-11 2015-09-30 华中科技大学同济医学院附属同济医院 具有肿瘤组织靶向性和抑癌基因修复性的重组溶瘤腺病毒Ad5-P16及其应用
JP7277466B2 (ja) * 2017-09-01 2023-05-19 インプラザー エー・ペー・エス 疾患の予防および／または治療における使用のためのワクチン
GB201804473D0 (en) * 2018-03-21 2018-05-02 Valo Therapeutics Oy Modified oncolytic adenoviruses
JP2022553870A (ja) * 2019-11-06 2022-12-26 メムゲン，インコーポレイテッド 複製促進腫瘍溶解性アデノウイルス

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055831A2 (fr) * 1998-04-24 1999-11-04 Onyx Pharmaceuticals, Inc. Vecteurs adenoviraux destines au traitement de maladies
WO2000030687A1 (fr) * 1998-11-19 2000-06-02 The Board Of Trustees Of The Leland Stanford Junior University Nouveau vecteur adenoviral et ses methodes de production et d'utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780406B1 (en) * 1994-03-21 2004-08-24 The Regents Of The University Of Michigan Inhibition of vascular smooth muscle cell proliferation administering a thymidine kinase gene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055831A2 (fr) * 1998-04-24 1999-11-04 Onyx Pharmaceuticals, Inc. Vecteurs adenoviraux destines au traitement de maladies
WO2000030687A1 (fr) * 1998-11-19 2000-06-02 The Board Of Trustees Of The Leland Stanford Junior University Nouveau vecteur adenoviral et ses methodes de production et d'utilisation

Also Published As

Publication number Publication date
WO2001002540A2 (fr) 2001-01-11
CA2373352A1 (fr) 2001-01-11
EP1218527A2 (fr) 2002-07-03
AU6057800A (en) 2001-01-22
WO2001002540A3 (fr) 2001-08-30
WO2001002540A9 (fr) 2001-09-20
JP2003504316A (ja) 2003-02-04
CN1357050A (zh) 2002-07-03

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