AU781496B2 - Activation and inhibition of the immune system - Google Patents
Activation and inhibition of the immune system Download PDFInfo
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- AU781496B2 AU781496B2 AU22062/01A AU2206201A AU781496B2 AU 781496 B2 AU781496 B2 AU 781496B2 AU 22062/01 A AU22062/01 A AU 22062/01A AU 2206201 A AU2206201 A AU 2206201A AU 781496 B2 AU781496 B2 AU 781496B2
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/06—Uses of viruses as vector in vitro
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- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9930616.9A GB9930616D0 (en) | 1999-12-24 | 1999-12-24 | Activation and inhibition of the immune system |
| GB9930616 | 1999-12-24 | ||
| PCT/GB2000/004925 WO2001047543A2 (en) | 1999-12-24 | 2000-12-22 | Activation and inhibition of the immune system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2206201A AU2206201A (en) | 2001-07-09 |
| AU781496B2 true AU781496B2 (en) | 2005-05-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU22062/01A Ceased AU781496B2 (en) | 1999-12-24 | 2000-12-22 | Activation and inhibition of the immune system |
Country Status (12)
| Country | Link |
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| US (2) | US7915009B2 (https=) |
| EP (2) | EP1244466B1 (https=) |
| JP (1) | JP2003518507A (https=) |
| CN (2) | CN1254272C (https=) |
| AT (1) | ATE390929T1 (https=) |
| AU (1) | AU781496B2 (https=) |
| CA (1) | CA2394880A1 (https=) |
| DE (1) | DE60038503T2 (https=) |
| ES (1) | ES2302707T3 (https=) |
| GB (1) | GB9930616D0 (https=) |
| NZ (1) | NZ519438A (https=) |
| WO (1) | WO2001047543A2 (https=) |
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| GB9930616D0 (en) | 1999-12-24 | 2000-02-16 | Mathilda & Terence Kennedy Ins | Activation and inhibition of the immune system |
| CA2432542A1 (en) * | 2000-12-22 | 2002-07-04 | Synovis Limited | Methods of modulating toll-related receptor (trr) signaling |
| GB0116249D0 (en) * | 2001-07-05 | 2001-08-29 | Imp College Innovations Ltd | Methods |
| JP2003055202A (ja) * | 2001-08-15 | 2003-02-26 | Hiroyuki Hanai | 炎症性腸疾患の予防・治療剤 |
| CA2493902A1 (en) * | 2002-05-29 | 2003-12-04 | Anges Mg, Inc. | Decoy composition for treating and preventing inflammatory disease |
| AU2002953094A0 (en) * | 2002-12-04 | 2002-12-19 | The University Of Queensland | Immunomodulating compositions, processes for their production and uses therefor |
| US20060257380A1 (en) * | 2002-09-19 | 2006-11-16 | Inst.Nat. De La Sante Et De La Recherche MED | Use of sirnas for gene silencing in antigen presenting cells |
| CA2516320C (en) | 2003-02-18 | 2015-05-26 | Kevin Slawin | Induced activation in dendritic cells |
| US20050147608A1 (en) * | 2003-05-08 | 2005-07-07 | Beth Israel Deaconess Medical Center, Inc. | Novel regulatory mechanisms of NF-kappaB |
| AR051836A1 (es) | 2004-11-30 | 2007-02-14 | Centocor Inc | Antagonistas de receptor 3 simil toll metodos y usos |
| CN100418532C (zh) * | 2005-06-17 | 2008-09-17 | 吕志民 | 治疗多种疾病的NF-κB化合物抑制剂 |
| EP1917038A4 (en) * | 2005-06-23 | 2010-01-13 | Baylor College Medicine | MODULATION OF NEGATIVE IMMUNETRULATORS AND APPLICATIONS FOR IMMUNOTHERAPY |
| CA2623153A1 (en) * | 2005-09-20 | 2007-03-29 | London Health Sciences Centre Research Inc. | The use of sirnas in organ storage/reperfusion solutions |
| DK1945820T3 (da) | 2005-10-27 | 2013-11-11 | Janssen Biotech Inc | Toll-lignende receptor-3-modulatorer, fremgangsmåder og anvendelser |
| CN102851295B (zh) * | 2006-08-28 | 2015-01-07 | 长春华普生物技术有限公司 | Toll 样受体调节性寡核苷酸及其用途 |
| JP2010505883A (ja) * | 2006-10-12 | 2010-02-25 | ザ ユニバーシティー オブ クイーンズランド | 免疫応答を調節するための組成物および方法 |
| CA2666667C (en) * | 2006-10-19 | 2023-06-20 | Baylor College Of Medicine | Generating an immune response by inducing cd40 and pattern recognition receptors |
| WO2008080195A1 (en) * | 2006-12-29 | 2008-07-10 | The University Of Queensland | Compositions and methods for treating or preventing unwanted immune responses |
| EP2331680B1 (en) * | 2008-09-22 | 2017-05-03 | Baylor College Of Medicine | Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters |
| WO2011146862A1 (en) | 2010-05-21 | 2011-11-24 | Bellicum Pharmaceuticals, Inc. | Methods for inducing selective apoptosis |
| EP2734240B1 (en) * | 2011-07-18 | 2018-03-21 | University Of Kentucky Research Foundation | Protection of cells from alu-rna-induced degenereation and inhibitors for protecting cells |
| US9434935B2 (en) | 2013-03-10 | 2016-09-06 | Bellicum Pharmaceuticals, Inc. | Modified caspase polypeptides and uses thereof |
| WO2014151960A2 (en) | 2013-03-14 | 2014-09-25 | Bellicum Pharmaceuticals, Inc. | Methods for controlling t cell proliferation |
| CA2912172A1 (en) | 2013-06-05 | 2014-12-11 | Bellicum Pharmaceuticals, Inc. | Methods for inducing partial apoptosis using caspase polypeptides |
| WO2015038959A2 (en) | 2013-09-12 | 2015-03-19 | Icahn School Of Medicine At Mount Sinai | T cell receptors that are specific to a fluorescent protein, transgenic animals and methods of their making, isolated t cells, and methods of use |
| US10934346B2 (en) | 2014-02-14 | 2021-03-02 | Bellicum Pharmaceuticals, Inc. | Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12 |
| WO2015187847A1 (en) * | 2014-06-03 | 2015-12-10 | Cure-It Lifesciences, Llc | Use of prostaglandin e1 (pge1) and misoprostol for treating chronic myelogenous/myeloid leukemia (cml) |
| US10888608B2 (en) | 2014-09-02 | 2021-01-12 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by MyD88 and CD40 polypeptides |
| ES2904301T3 (es) | 2014-11-03 | 2022-04-04 | Academisch Ziekenhuis Leiden H O D N Leids Univ Medisch Centrum | Receptores de células T dirigidos contra Bob1 y usos de los mismos |
| AU2015360502A1 (en) | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| US10420836B2 (en) | 2015-10-08 | 2019-09-24 | Emory University | Methods of immunizing a subject and compositions related thereto |
| CN114222737B (zh) | 2019-05-31 | 2024-07-26 | 詹森药业有限公司 | NF-κB诱导激酶的小分子抑制剂 |
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| EP0894855A2 (en) * | 1997-07-31 | 1999-02-03 | Smithkline Beecham Corporation | Human I kappa B-beta transcription factor |
| EP0897009A2 (en) * | 1997-08-04 | 1999-02-17 | Smithkline Beecham Plc | HKABY60 polypeptides |
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| GB9930616D0 (en) | 1999-12-24 | 2000-02-16 | Mathilda & Terence Kennedy Ins | Activation and inhibition of the immune system |
| GB0005345D0 (en) | 2000-03-06 | 2000-04-26 | Mathilda & Terence Kennedy Ins | Methods of treating sepsis septic shock and inflammation |
| CA2432542A1 (en) | 2000-12-22 | 2002-07-04 | Synovis Limited | Methods of modulating toll-related receptor (trr) signaling |
| GB0116249D0 (en) | 2001-07-05 | 2001-08-29 | Imp College Innovations Ltd | Methods |
-
1999
- 1999-12-24 GB GBGB9930616.9A patent/GB9930616D0/en not_active Ceased
-
2000
- 2000-12-22 NZ NZ519438A patent/NZ519438A/en not_active IP Right Cessation
- 2000-12-22 CN CNB008191050A patent/CN1254272C/zh not_active Expired - Fee Related
- 2000-12-22 JP JP2001548135A patent/JP2003518507A/ja active Pending
- 2000-12-22 DE DE60038503T patent/DE60038503T2/de not_active Expired - Lifetime
- 2000-12-22 AT AT00985660T patent/ATE390929T1/de not_active IP Right Cessation
- 2000-12-22 EP EP00985660A patent/EP1244466B1/en not_active Expired - Lifetime
- 2000-12-22 CN CNB200610051522XA patent/CN100563707C/zh not_active Expired - Fee Related
- 2000-12-22 US US10/168,805 patent/US7915009B2/en not_active Expired - Fee Related
- 2000-12-22 ES ES00985660T patent/ES2302707T3/es not_active Expired - Lifetime
- 2000-12-22 CA CA002394880A patent/CA2394880A1/en not_active Abandoned
- 2000-12-22 AU AU22062/01A patent/AU781496B2/en not_active Ceased
- 2000-12-22 WO PCT/GB2000/004925 patent/WO2001047543A2/en not_active Ceased
- 2000-12-22 EP EP07014428A patent/EP1852123A3/en not_active Withdrawn
-
2007
- 2007-12-06 US US11/987,956 patent/US20080124322A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998008955A1 (en) * | 1996-08-26 | 1998-03-05 | Signal Pharmaceuticals, Inc. | Stimulus-inducible i (kappa)b kinase [ikk] signalsome |
| EP0894855A2 (en) * | 1997-07-31 | 1999-02-03 | Smithkline Beecham Corporation | Human I kappa B-beta transcription factor |
| EP0897009A2 (en) * | 1997-08-04 | 1999-02-17 | Smithkline Beecham Plc | HKABY60 polypeptides |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1852123A2 (en) | 2007-11-07 |
| EP1852123A3 (en) | 2008-09-10 |
| US20030153518A1 (en) | 2003-08-14 |
| ATE390929T1 (de) | 2008-04-15 |
| DE60038503D1 (de) | 2008-05-15 |
| US7915009B2 (en) | 2011-03-29 |
| CN1817367A (zh) | 2006-08-16 |
| US20080124322A1 (en) | 2008-05-29 |
| EP1244466B1 (en) | 2008-04-02 |
| ES2302707T3 (es) | 2008-08-01 |
| WO2001047543A2 (en) | 2001-07-05 |
| CA2394880A1 (en) | 2001-07-05 |
| AU2206201A (en) | 2001-07-09 |
| EP1244466A2 (en) | 2002-10-02 |
| CN100563707C (zh) | 2009-12-02 |
| CN1434718A (zh) | 2003-08-06 |
| WO2001047543A3 (en) | 2002-01-17 |
| GB9930616D0 (en) | 2000-02-16 |
| NZ519438A (en) | 2004-03-26 |
| JP2003518507A (ja) | 2003-06-10 |
| CN1254272C (zh) | 2006-05-03 |
| DE60038503T2 (de) | 2009-04-30 |
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