AU780994B2 - Bone marrow transplantation for treatment of stroke - Google Patents

Bone marrow transplantation for treatment of stroke Download PDF

Info

Publication number
AU780994B2
AU780994B2 AU51300/00A AU5130000A AU780994B2 AU 780994 B2 AU780994 B2 AU 780994B2 AU 51300/00 A AU51300/00 A AU 51300/00A AU 5130000 A AU5130000 A AU 5130000A AU 780994 B2 AU780994 B2 AU 780994B2
Authority
AU
Australia
Prior art keywords
bone marrow
cells
nervous tissue
tissue
marrow cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU51300/00A
Other languages
English (en)
Other versions
AU5130000A (en
Inventor
Michael Chopp
Yi Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henry Ford Health System
Original Assignee
Henry Ford Health System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henry Ford Health System filed Critical Henry Ford Health System
Publication of AU5130000A publication Critical patent/AU5130000A/en
Application granted granted Critical
Publication of AU780994B2 publication Critical patent/AU780994B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
AU51300/00A 1999-05-14 2000-05-11 Bone marrow transplantation for treatment of stroke Ceased AU780994B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13434499P 1999-05-14 1999-05-14
US60/134344 1999-05-14
PCT/US2000/012875 WO2000069448A1 (en) 1999-05-14 2000-05-11 Bone marrow transplantation for treatment of stroke

Publications (2)

Publication Number Publication Date
AU5130000A AU5130000A (en) 2000-12-05
AU780994B2 true AU780994B2 (en) 2005-04-28

Family

ID=22462927

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51300/00A Ceased AU780994B2 (en) 1999-05-14 2000-05-11 Bone marrow transplantation for treatment of stroke

Country Status (9)

Country Link
US (1) US20090162327A1 (enExample)
EP (1) EP1183035B1 (enExample)
JP (1) JP2002544234A (enExample)
AU (1) AU780994B2 (enExample)
CA (1) CA2373808C (enExample)
DK (1) DK1183035T3 (enExample)
ES (1) ES2531592T3 (enExample)
PT (1) PT1183035E (enExample)
WO (1) WO2000069448A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653134B2 (en) * 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
US8017112B2 (en) 1999-05-14 2011-09-13 Henry Ford Health System Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
US20050169896A1 (en) * 1999-05-14 2005-08-04 Henry Ford Health System Bone marrow transplantation for treatment of stroke
JP2003507349A (ja) * 1999-08-18 2003-02-25 ザ ゼネラル ホスピタル コーポレーション 中枢神経系への損傷からの回復を促進する方法、組成物およびキット
US6749850B1 (en) 1999-08-18 2004-06-15 The General Hospital Corporation Methods, compositions and kits for promoting recovery from damage to the central nervous system
WO2001075094A1 (en) * 2000-04-04 2001-10-11 Thomas Jefferson University Application of myeloid-origin cells to the nervous system
KR100947577B1 (ko) 2000-06-26 2010-03-15 엔씨 메디컬 리서치 가부시키가이샤 신경계 세포로 분화할 수 있는 세포를 포함하는 세포분획
ES2180433B1 (es) * 2001-05-28 2004-05-16 Universidad Miguel Hernandez De Elche. Empleo de celulas madre hematopoyeticas en la generacion de celulas madre neurales.
US9969980B2 (en) 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
WO2003038075A1 (en) * 2001-10-30 2003-05-08 Renomedix Institute Inc. Method of inducing differentiation of mesodermal stem cells, es cells or immortalized cells into nervous system cells
CN1638775A (zh) * 2002-01-04 2005-07-13 亨利福尔德健康组织 治疗疾病和损伤用的氧化氮供体
US7687505B2 (en) 2002-01-14 2010-03-30 Board Of Trustees Of The University Of Illinois Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US9969977B2 (en) 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
US20060210544A1 (en) 2003-06-27 2006-09-21 Renomedix Institute, Inc. Internally administered therapeutic agents for cranial nerve diseases comprising mesenchymal cells as an active ingredient
KR101130220B1 (ko) * 2003-06-27 2012-04-13 엔씨 메디컬 리서치 가부시키가이샤 간엽계 세포를 유효 성분으로 하는 뇌신경 질환 치료용 체내 투여용 약제
RU2283121C2 (ru) * 2004-11-29 2006-09-10 Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН Способ лечения инсульта
US20080107632A1 (en) * 2006-09-06 2008-05-08 Henrich Cheng Fibrin glue composition for repairing nerve damage and methods thereof
WO2008156728A1 (en) 2007-06-15 2008-12-24 Neuronyx, Inc. Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro
JP5276816B2 (ja) * 2007-09-10 2013-08-28 肇 井上 神経機能改善剤
CA2753833A1 (en) * 2008-02-28 2009-09-03 Henry Ford Health System Compositions and methods for using stromal cells to enhance treatment of central nervous system injuries
CN105072914B (zh) * 2013-02-06 2018-09-21 Nc医学研究公司 用于治疗神经变性的细胞疗法
CN105814196A (zh) * 2013-10-14 2016-07-27 哈达斯特医疗研究服务和开发有限公司 终末分化的神经元谱系的获得方法及其用途
WO2015174087A1 (ja) * 2014-05-16 2015-11-19 公益財団法人先端医療振興財団 脳梗塞の予防及び/又は治療の為の医薬
RU2612981C1 (ru) * 2015-12-21 2017-03-14 Алексей Сергеевич Бывальцев Способ лечения ишемического инсульта
US11464804B1 (en) 2017-11-15 2022-10-11 Enrico Stazzone Intrathecal multifactorial infusion of heterogeneous autologous cell therapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666828A (en) * 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) * 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) * 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) * 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5851832A (en) * 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
CA2159738A1 (en) * 1993-04-13 1994-10-27 Eugene O. Major Use of neuro-derived fetal cell lines for transplantation therapy
US6653134B2 (en) * 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
AU3888699A (en) * 1998-05-07 1999-11-23 University Of South Florida Bone marrow cells as a source of neurons for brain and spinal cord repair
GB9904281D0 (en) * 1999-02-24 1999-04-21 Reneuron Ltd Transplantation

Also Published As

Publication number Publication date
US20090162327A1 (en) 2009-06-25
CA2373808C (en) 2011-04-19
EP1183035A4 (en) 2003-05-07
AU5130000A (en) 2000-12-05
EP1183035B1 (en) 2014-12-03
PT1183035E (pt) 2015-03-04
CA2373808A1 (en) 2000-11-23
EP1183035A1 (en) 2002-03-06
DK1183035T3 (en) 2015-03-09
ES2531592T3 (es) 2015-03-17
WO2000069448A1 (en) 2000-11-23
JP2002544234A (ja) 2002-12-24

Similar Documents

Publication Publication Date Title
AU780994B2 (en) Bone marrow transplantation for treatment of stroke
US20050169896A1 (en) Bone marrow transplantation for treatment of stroke
Philips et al. Neuroprotective and behavioral efficacy of nerve growth factor—Transfected hippocampal progenitor cell transplants after experimental traumatic brain injury
US8940293B2 (en) Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
EP1096941B1 (en) Bone marrow cells as a source of neurons for brain and spinal cord repair
US7582292B2 (en) Adipose tissue derived stromal cells for the treatment of neurological disorders
US8945919B2 (en) Methods and composition for treating neural degeneration
US20090169527A1 (en) Materials from bone marrow stromal cells for use in forming blood vessels and producing angiogenic and trophic factors
US6214334B1 (en) Compositions and methods for producing and using homogenous neuronal cell transplants to treat neurodegenerative disorders and brain and spinal cord injuries
Du et al. Transplantation of artificial neural construct partly improved spinal tissue repair and functional recovery in rats with spinal cord transection
Zhu et al. Stem cell transplantation for amyotrophic lateral sclerosis
US6254865B1 (en) Method of treating huntington's disease using HNT neurons
US20100119493A1 (en) Telencephalic Glial-Restricted Cell Populations and Related Compositions and Methods
Cho et al. The behavioral effect of human mesenchymal stem cell transplantation in cold brain injured rats
US7459152B2 (en) Erythropoietin administration to improve graft survival
WO2010030199A1 (en) Stem cell culture
Donsante et al. Stem Cells for Amyotrophic Lateral Sclerosis
Morris et al. Neural Stem Cell Intervention in Traumatic Brain Injury
Shulman et al. Application of autologous peripheral blood mononuclear cells into the area of spinal cord injury in a subacute period: a pilot study in pigs
Cords 1.1. Ventral Horn Implants of hNT Neurons Improve Motor Function in a Transgenic Mouse Model of ALS. AE
Freed Cell transplantation: brain
Dhib-Jalbut et al. Delivery of transgenically modified adult bone marrow cells to the rodent central nervous system
Neimat et al. Investigational Surgical Therapies
LECTURE Eleventh Annual Conference of the American Society for Neural Transplantation & Repair
HK1134688B (en) Use of a composition contaning human umbilical cord blood-derived mesenchymal stem cell for inducing differentiation and proliferation of neural precursor cells or neural stem cells to neural cells