AU762575B2 - Nitrocoumarins for detecting all micro-organisms - Google Patents
Nitrocoumarins for detecting all micro-organisms Download PDFInfo
- Publication number
- AU762575B2 AU762575B2 AU11639/00A AU1163900A AU762575B2 AU 762575 B2 AU762575 B2 AU 762575B2 AU 11639/00 A AU11639/00 A AU 11639/00A AU 1163900 A AU1163900 A AU 1163900A AU 762575 B2 AU762575 B2 AU 762575B2
- Authority
- AU
- Australia
- Prior art keywords
- nitrocoumarin
- compound
- microorganisms
- microorganism
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
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- YMCDYRGMTRCAPZ-UHFFFAOYSA-N ethyl 2-acetyl-3-oxobutanoate Chemical compound CCOC(=O)C(C(C)=O)C(C)=O YMCDYRGMTRCAPZ-UHFFFAOYSA-N 0.000 description 1
- KQWWVLVLVYYYDT-UHFFFAOYSA-N ethyl 3-oxohexanoate Chemical group CCCC(=O)CC(=O)OCC KQWWVLVLVYYYDT-UHFFFAOYSA-N 0.000 description 1
- XYIBRDXRRQCHLP-UHFFFAOYSA-N ethyl acetoacetate Chemical compound CCOC(=O)CC(C)=O XYIBRDXRRQCHLP-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000007773 growth pattern Effects 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 230000000147 hypnotic effect Effects 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- LZXXNPOYQCLXRS-UHFFFAOYSA-N methyl 4-aminobenzoate Chemical compound COC(=O)C1=CC=C(N)C=C1 LZXXNPOYQCLXRS-UHFFFAOYSA-N 0.000 description 1
- YOJAHJGBFDPSDI-UHFFFAOYSA-N methyl 4-nitrobenzoate Chemical compound COC(=O)C1=CC=C([N+]([O-])=O)C=C1 YOJAHJGBFDPSDI-UHFFFAOYSA-N 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229940076266 morganella morganii Drugs 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- UPSFMJHZUCSEHU-JYGUBCOQSA-N n-[(2s,3r,4r,5s,6r)-2-[(2r,3s,4r,5r,6s)-5-acetamido-4-hydroxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide Chemical compound CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](O)[C@@H](NC(C)=O)[C@H](OC=2C=C3OC(=O)C=C(C)C3=CC=2)O[C@@H]1CO UPSFMJHZUCSEHU-JYGUBCOQSA-N 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 108020001162 nitroreductase Proteins 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229910001495 sodium tetrafluoroborate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000013190 sterility testing Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9814101A FR2785620B1 (fr) | 1998-11-05 | 1998-11-05 | Detection de tous micro-organismes dans un echantillon |
| FR98/14101 | 1998-11-05 | ||
| PCT/FR1999/002704 WO2000028073A1 (fr) | 1998-11-05 | 1999-11-05 | Nitrocoumarines pour la detection de tous micro-organismes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1163900A AU1163900A (en) | 2000-05-29 |
| AU762575B2 true AU762575B2 (en) | 2003-06-26 |
Family
ID=9532554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU11639/00A Expired AU762575B2 (en) | 1998-11-05 | 1999-11-05 | Nitrocoumarins for detecting all micro-organisms |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6555332B2 (enExample) |
| EP (1) | EP1124986B1 (enExample) |
| JP (1) | JP5116918B2 (enExample) |
| AT (1) | ATE266101T1 (enExample) |
| AU (1) | AU762575B2 (enExample) |
| CA (1) | CA2348710C (enExample) |
| DE (1) | DE69917061T2 (enExample) |
| ES (1) | ES2221485T3 (enExample) |
| FR (1) | FR2785620B1 (enExample) |
| WO (1) | WO2000028073A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7687239B2 (en) * | 2003-07-12 | 2010-03-30 | Accelrs Technology Corporation | Sensitive and rapid determination of antimicrobial susceptibility |
| US20120077206A1 (en) * | 2003-07-12 | 2012-03-29 | Accelr8 Technology Corporation | Rapid Microbial Detection and Antimicrobial Susceptibility Testing |
| DE602005011584D1 (de) * | 2004-03-22 | 2009-01-22 | Evonik Goldschmidt Gmbh | Verfahren und testkit zum nachweis und zur quantifizierung von organismen |
| GB0505777D0 (en) * | 2005-03-22 | 2005-04-27 | Amersham Biosciences Uk Ltd | Enzyme detection method and reagent |
| WO2008030120A1 (en) * | 2006-09-07 | 2008-03-13 | Auckland Uniservices Limited | A method for the fluorescent detection of nitroreductase activity using nitro-substituted aromatic compounds |
| FR2916762B1 (fr) * | 2007-05-31 | 2013-11-15 | Biomerieux Sa | Nouveaux substrats enzymatiques de nitroreductase |
| FR2937338B1 (fr) | 2008-10-17 | 2013-03-22 | Biomerieux Sa | Milieu reactionnel pour la detection et/ou l'identification de bacteries du genre legionella |
| FR2948681A1 (fr) | 2009-07-30 | 2011-02-04 | Biomerieux Sa | Nouveaux substrats enzymatiques de nitroreductases |
| FR2948682A1 (fr) | 2009-07-30 | 2011-02-04 | Biomerieux Sa | Nouveaux substrats enzymatiques de nitroreductase |
| FR2948683B1 (fr) * | 2009-07-30 | 2011-08-19 | Biomerieux Sa | Nouveaux substrats enzymatiques de nitroreductase |
| EP2453021A1 (en) | 2010-11-11 | 2012-05-16 | Biosynth AG | Novel indicator compounds |
| US8828678B2 (en) | 2010-11-16 | 2014-09-09 | Enzo Life Sciences, Inc. | Self-immolative probes for enzyme activity detection |
| US10254204B2 (en) | 2011-03-07 | 2019-04-09 | Accelerate Diagnostics, Inc. | Membrane-assisted purification |
| US9434937B2 (en) | 2011-03-07 | 2016-09-06 | Accelerate Diagnostics, Inc. | Rapid cell purification systems |
| US9677109B2 (en) | 2013-03-15 | 2017-06-13 | Accelerate Diagnostics, Inc. | Rapid determination of microbial growth and antimicrobial susceptibility |
| AU2016243656A1 (en) | 2015-03-30 | 2017-11-09 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
| US10253355B2 (en) | 2015-03-30 | 2019-04-09 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0091837B1 (en) * | 1982-04-14 | 1989-07-26 | Radiometer Corporate Development Limited | Microbiological test processes and apparatus |
| US4728608A (en) * | 1985-04-08 | 1988-03-01 | Cambridge Bioscience Corporation | Bacterial screening system with enhanced shelf life |
| ES2076313T3 (es) * | 1989-05-08 | 1995-11-01 | Metal Box Plc | Deteccion electroquimica del crecimiento de microorganismos. |
| US5055594A (en) * | 1990-07-19 | 1991-10-08 | Becton, Dickinson And Company | Fluorogenic trypotophanase substrates |
| US5081044A (en) * | 1990-09-28 | 1992-01-14 | Miles Inc. | Detection of hydrogen peroxide with optical indicator chalcogen compounds |
| US5851785A (en) * | 1992-02-04 | 1998-12-22 | Kyowa Medex Co., Ltd. | Method of quantitative determination of substances using coumarin derivatives |
| US5696157A (en) * | 1996-11-15 | 1997-12-09 | Molecular Probes, Inc. | Sulfonated derivatives of 7-aminocoumarin |
-
1998
- 1998-11-05 FR FR9814101A patent/FR2785620B1/fr not_active Expired - Lifetime
-
1999
- 1999-11-05 DE DE69917061T patent/DE69917061T2/de not_active Expired - Lifetime
- 1999-11-05 AT AT99971865T patent/ATE266101T1/de not_active IP Right Cessation
- 1999-11-05 EP EP99971865A patent/EP1124986B1/fr not_active Expired - Lifetime
- 1999-11-05 JP JP2000581239A patent/JP5116918B2/ja not_active Expired - Lifetime
- 1999-11-05 CA CA2348710A patent/CA2348710C/fr not_active Expired - Lifetime
- 1999-11-05 AU AU11639/00A patent/AU762575B2/en not_active Expired
- 1999-11-05 WO PCT/FR1999/002704 patent/WO2000028073A1/fr not_active Ceased
- 1999-11-05 ES ES99971865T patent/ES2221485T3/es not_active Expired - Lifetime
-
2001
- 2001-05-04 US US09/848,250 patent/US6555332B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69917061D1 (de) | 2004-06-09 |
| EP1124986A1 (fr) | 2001-08-22 |
| FR2785620A1 (fr) | 2000-05-12 |
| FR2785620B1 (fr) | 2003-02-07 |
| JP2002529478A (ja) | 2002-09-10 |
| DE69917061T2 (de) | 2005-04-21 |
| WO2000028073A1 (fr) | 2000-05-18 |
| US6555332B2 (en) | 2003-04-29 |
| CA2348710C (fr) | 2011-09-13 |
| CA2348710A1 (fr) | 2000-05-18 |
| JP5116918B2 (ja) | 2013-01-09 |
| EP1124986B1 (fr) | 2004-05-06 |
| AU1163900A (en) | 2000-05-29 |
| ATE266101T1 (de) | 2004-05-15 |
| US20020031795A1 (en) | 2002-03-14 |
| ES2221485T3 (es) | 2004-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |