AU761459B2 - A novel bioactive product and its use - Google Patents
A novel bioactive product and its use Download PDFInfo
- Publication number
- AU761459B2 AU761459B2 AU15617/00A AU1561700A AU761459B2 AU 761459 B2 AU761459 B2 AU 761459B2 AU 15617/00 A AU15617/00 A AU 15617/00A AU 1561700 A AU1561700 A AU 1561700A AU 761459 B2 AU761459 B2 AU 761459B2
- Authority
- AU
- Australia
- Prior art keywords
- textile product
- weight
- product according
- fiber
- bioactive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000000975 bioactive effect Effects 0.000 title claims description 28
- 239000000835 fiber Substances 0.000 claims abstract description 52
- 239000004753 textile Substances 0.000 claims abstract description 38
- 239000005313 bioactive glass Substances 0.000 claims abstract description 36
- 239000007943 implant Substances 0.000 claims description 23
- 239000000463 material Substances 0.000 claims description 16
- 210000001519 tissue Anatomy 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 13
- 210000000988 bone and bone Anatomy 0.000 claims description 11
- 230000008468 bone growth Effects 0.000 claims description 10
- 239000003814 drug Substances 0.000 claims description 6
- 229940079593 drug Drugs 0.000 claims description 6
- 239000000945 filler Substances 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 4
- 239000000741 silica gel Substances 0.000 claims description 4
- 229910002027 silica gel Inorganic materials 0.000 claims description 4
- 239000004744 fabric Substances 0.000 claims description 3
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 3
- 230000001939 inductive effect Effects 0.000 claims description 3
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 3
- 210000004872 soft tissue Anatomy 0.000 claims description 3
- 210000004746 tooth root Anatomy 0.000 claims description 3
- KKCBUQHMOMHUOY-UHFFFAOYSA-N Na2O Inorganic materials [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 claims description 2
- 239000011230 binding agent Substances 0.000 claims description 2
- 239000000047 product Substances 0.000 description 28
- 239000011521 glass Substances 0.000 description 8
- 239000002245 particle Substances 0.000 description 8
- 239000002131 composite material Substances 0.000 description 7
- 239000004005 microsphere Substances 0.000 description 6
- 241000894007 species Species 0.000 description 6
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 4
- 239000012890 simulated body fluid Substances 0.000 description 4
- 239000010936 titanium Substances 0.000 description 4
- 229910052719 titanium Inorganic materials 0.000 description 4
- 239000012620 biological material Substances 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 230000011164 ossification Effects 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 229910004298 SiO 2 Inorganic materials 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000006112 glass ceramic composition Substances 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 230000004962 physiological condition Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 238000007788 roughening Methods 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- QXJJQWWVWRCVQT-UHFFFAOYSA-K calcium;sodium;phosphate Chemical compound [Na+].[Ca+2].[O-]P([O-])([O-])=O QXJJQWWVWRCVQT-UHFFFAOYSA-K 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229910000040 hydrogen fluoride Inorganic materials 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000003049 inorganic solvent Substances 0.000 description 1
- 229910001867 inorganic solvent Inorganic materials 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 238000010883 osseointegration Methods 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C13/00—Fibre or filament compositions
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C3/00—Glass compositions
- C03C3/04—Glass compositions containing silica
- C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
- C03C3/097—Glass compositions containing silica with 40% to 90% silica, by weight containing phosphorus, niobium or tantalum
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
- C03C4/0014—Biodegradable glass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00329—Glasses, e.g. bioglass
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Geochemistry & Mineralogy (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Ceramic Engineering (AREA)
- Biodiversity & Conservation Biology (AREA)
- Composite Materials (AREA)
- Biomedical Technology (AREA)
- Materials For Medical Uses (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Dental Preparations (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI982684 | 1998-12-11 | ||
| FI982684A FI110063B (fi) | 1998-12-11 | 1998-12-11 | Uusi bioaktiivinen tuote ja sen käyttö |
| PCT/FI1999/000961 WO2000035509A1 (en) | 1998-12-11 | 1999-11-19 | A novel bioactive product and its use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1561700A AU1561700A (en) | 2000-07-03 |
| AU761459B2 true AU761459B2 (en) | 2003-06-05 |
Family
ID=8553092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU15617/00A Ceased AU761459B2 (en) | 1998-12-11 | 1999-11-19 | A novel bioactive product and its use |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6517857B2 (enExample) |
| EP (1) | EP1137448B1 (enExample) |
| JP (1) | JP2002532158A (enExample) |
| AT (1) | ATE316389T1 (enExample) |
| AU (1) | AU761459B2 (enExample) |
| CA (1) | CA2354850C (enExample) |
| DE (1) | DE69929625T2 (enExample) |
| DK (1) | DK1137448T3 (enExample) |
| ES (1) | ES2255318T3 (enExample) |
| FI (1) | FI110063B (enExample) |
| WO (1) | WO2000035509A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI20000515A0 (fi) * | 2000-03-07 | 2000-03-07 | Heimo Ylaenen | Menetelmä bioaktiivisen lasin pinnan karhentamiseksi |
| US7005135B2 (en) * | 2001-01-30 | 2006-02-28 | Ethicon Inc. | Glass scaffolds with controlled resorption rates and methods for making same |
| FI117963B (fi) | 2001-04-26 | 2007-05-15 | Eija Marjut Pirhonen | Luuta korvaavat materiaalit |
| CA2554777C (en) | 2004-02-03 | 2012-10-09 | Orhun K. Muratoglu | Highly crystalline cross-linked oxidation-resistant polyethylene |
| EP1611906A1 (en) * | 2004-06-30 | 2006-01-04 | YLI-URPO, Antti | A multilayer material |
| EP2441780A1 (en) | 2005-08-22 | 2012-04-18 | The General Hospital Corporation d/b/a Massachusetts General Hospital | Highly Crystalline Polyethylene |
| US20070258916A1 (en) * | 2006-04-14 | 2007-11-08 | Oregon Health & Science University | Oral compositions for treating tooth hypersensitivity |
| EP1872806A1 (en) * | 2006-06-28 | 2008-01-02 | Vivoxid Oy | Implant, its uses and methods for making it |
| WO2008000888A2 (en) * | 2006-06-28 | 2008-01-03 | Vivoxid Oy | Implant containing a source of oxygen |
| KR100791518B1 (ko) * | 2006-12-21 | 2008-01-04 | 단국대학교 산학협력단 | 생체활성 유리 나노섬유(ｂｇｎｆ) 및 그 제조방법 |
| KR100791512B1 (ko) | 2006-12-21 | 2008-01-04 | 단국대학교 산학협력단 | 나노구조로 이루어진 하이브리드형 조직재생용 멤브레인과스캐폴드 및 그들의 제조방법 |
| DE102007018200A1 (de) * | 2007-04-16 | 2008-10-23 | Gehl, Gerolf, Dr. | Verfahren zum Herstellen und insbesondere zum Wiederherstellen einer Gewebestruktur |
| WO2009096945A1 (en) * | 2008-01-29 | 2009-08-06 | Zimmer, Inc. | Implant device for use in an implant system |
| US20100136086A1 (en) * | 2008-05-12 | 2010-06-03 | Day Thomas E | Dynamic bioactive nanofiber scaffolding |
| US9402724B2 (en) | 2008-05-12 | 2016-08-02 | Mo-Sci Corporation | Dynamic bioactive nanofiber scaffolding |
| KR101047897B1 (ko) * | 2008-10-22 | 2011-07-08 | 단국대학교 산학협력단 | 단백질 결합형 생체활성유리 나노섬유 및 이의 제조방법 |
| US9775721B2 (en) | 2009-07-10 | 2017-10-03 | Bio2 Technologies, Inc. | Resorbable interbody device |
| US8652368B2 (en) | 2009-07-10 | 2014-02-18 | Bio2 Technologies, Inc. | Devices and methods for tissue engineering |
| US20110206828A1 (en) * | 2009-07-10 | 2011-08-25 | Bio2 Technologies, Inc. | Devices and Methods for Tissue Engineering |
| EP2493424A4 (en) * | 2009-10-29 | 2014-04-30 | Prosidyan Inc | MATERIAL FOR BONE GRAFT |
| WO2011053719A1 (en) | 2009-10-29 | 2011-05-05 | Prosidyan, Inc. | Dynamic bioactive bone graft material having an engineered porosity |
| US8551525B2 (en) | 2010-12-23 | 2013-10-08 | Biostructures, Llc | Bone graft materials and methods |
| BR102013020961A2 (pt) | 2013-08-12 | 2016-03-08 | Univ Fed De São Carlos | composição vítrea, fibras e tecidos vítreos bioativos e artigos |
| US10238507B2 (en) | 2015-01-12 | 2019-03-26 | Surgentec, Llc | Bone graft delivery system and method for using same |
| US11013836B2 (en) * | 2016-06-16 | 2021-05-25 | The Curators Of The University Of Missouri | Inorganic biodegradable substrates for devices and systems |
| US10687828B2 (en) | 2018-04-13 | 2020-06-23 | Surgentec, Llc | Bone graft delivery system and method for using same |
| US11116647B2 (en) | 2018-04-13 | 2021-09-14 | Surgentec, Llc | Bone graft delivery system and method for using same |
| TWI890935B (zh) * | 2022-03-17 | 2025-07-21 | 巨晰光纖股份有限公司 | 用於再生醫材之生物玻璃纖維及其應用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991012032A1 (en) * | 1990-02-08 | 1991-08-22 | S.E.I.P.I. Società Esportazione Importazione Prodotti Industriali S.P.A. | Bioactive vitreous composition for bone implants, filaments made therefrom and method |
| WO1995014127A1 (en) * | 1993-11-15 | 1995-05-26 | The Trustees Of The University Of Pennsylvania | Composite materials using bone bioactive glass and ceramic fibers |
| WO1996021628A1 (en) * | 1995-01-13 | 1996-07-18 | Maria Brink | Novel bioactive glasses and their use |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1477899A (en) * | 1973-09-17 | 1977-06-29 | Leitz Ernst Gmbh | Manufacture of therapeutically useful composite materials |
| US4604097A (en) * | 1985-02-19 | 1986-08-05 | University Of Dayton | Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments |
| NZ234718A (en) * | 1989-08-11 | 1992-05-26 | Saint Gobain Isover | Decomposable glass fibres |
| JPH06116114A (ja) * | 1992-10-09 | 1994-04-26 | Nikon Corp | 骨充填材 |
| FI103715B1 (fi) * | 1997-04-21 | 1999-08-31 | Heimo Ylaenen | Uusi komposiitti ja sen käyttö |
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1998
- 1998-12-11 FI FI982684A patent/FI110063B/fi not_active IP Right Cessation
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1999
- 1999-11-19 AU AU15617/00A patent/AU761459B2/en not_active Ceased
- 1999-11-19 CA CA002354850A patent/CA2354850C/en not_active Expired - Fee Related
- 1999-11-19 EP EP99958198A patent/EP1137448B1/en not_active Expired - Lifetime
- 1999-11-19 ES ES99958198T patent/ES2255318T3/es not_active Expired - Lifetime
- 1999-11-19 WO PCT/FI1999/000961 patent/WO2000035509A1/en not_active Ceased
- 1999-11-19 DE DE69929625T patent/DE69929625T2/de not_active Expired - Fee Related
- 1999-11-19 JP JP2000587827A patent/JP2002532158A/ja active Pending
- 1999-11-19 AT AT99958198T patent/ATE316389T1/de not_active IP Right Cessation
- 1999-11-19 DK DK99958198T patent/DK1137448T3/da active
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- 2001-06-07 US US09/875,017 patent/US6517857B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991012032A1 (en) * | 1990-02-08 | 1991-08-22 | S.E.I.P.I. Società Esportazione Importazione Prodotti Industriali S.P.A. | Bioactive vitreous composition for bone implants, filaments made therefrom and method |
| WO1995014127A1 (en) * | 1993-11-15 | 1995-05-26 | The Trustees Of The University Of Pennsylvania | Composite materials using bone bioactive glass and ceramic fibers |
| WO1996021628A1 (en) * | 1995-01-13 | 1996-07-18 | Maria Brink | Novel bioactive glasses and their use |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1137448B1 (en) | 2006-01-25 |
| FI982684L (fi) | 2000-06-12 |
| EP1137448A1 (en) | 2001-10-04 |
| CA2354850C (en) | 2009-03-24 |
| DE69929625D1 (de) | 2006-04-13 |
| DE69929625T2 (de) | 2006-08-10 |
| DK1137448T3 (da) | 2006-05-08 |
| AU1561700A (en) | 2000-07-03 |
| JP2002532158A (ja) | 2002-10-02 |
| ATE316389T1 (de) | 2006-02-15 |
| US20010041325A1 (en) | 2001-11-15 |
| ES2255318T3 (es) | 2006-06-16 |
| US6517857B2 (en) | 2003-02-11 |
| CA2354850A1 (en) | 2000-06-22 |
| FI110063B (fi) | 2002-11-29 |
| WO2000035509A1 (en) | 2000-06-22 |
| FI982684A0 (fi) | 1998-12-11 |
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